Zobrazeno 1 - 10 of 89 pro vyhledávání: '"Wendy N. Jefferson"'
1
Akademický článek
Multiple tissue-specific epigenetic alterations regulate persistent gene expression changes following developmental DES exposure in mouse reproductive tissues
Autor: Tanner B. Jefferson, Tianyuan Wang, Wendy N. Jefferson, Yin Li, Katherine J. Hamilton, Paul A. Wade, Carmen J. Williams, Kenneth S. Korach
Publikováno v: Epigenetics, Vol 18, Iss 1 (2023)
Clinically, developmental exposure to the endocrine disrupting chemical, diethylstilboestrol (DES), results in long-term male and female infertility. Experimentally, developmental exposure to DES results in abnormal reproductive tract phenotypes in m
Externí odkaz: https://doaj.org/article/5dcfad8a24244727a47b62f679c43874
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3
Supplementary Figures S1-4 from SIX1 Regulates Aberrant Endometrial Epithelial Cell Differentiation and Cancer Latency Following Developmental Estrogenic Chemical Exposure
Autor: Carmen J. Williams, Charles E. Wood, Wendy N. Jefferson, Alisa A. Suen
Supplementary Figure S1. Six1 transcript and protein expression in Six 1conditional knockout mice following neonatal DES exposure. Supplementary Figure S2. Supplementary Figure S3. Supplementary Figure S4. CK14/18 staining in normal and abnormal uter
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0992c93038d7ca951e0f6266b28b0097
https://doi.org/10.1158/1541-7786.22513378.v1
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5
Supplementary Table 2 from SIX1 Regulates Aberrant Endometrial Epithelial Cell Differentiation and Cancer Latency Following Developmental Estrogenic Chemical Exposure
Autor: Carmen J. Williams, Charles E. Wood, Wendy N. Jefferson, Alisa A. Suen
Table S2A: 2,856 DEGs CON-Six1d/d versus CON-Six1+/+ Table S2B: GO Categories from 2,856 DEGs CON-Six1d/d versus CON-Six1+/+ Table S2C: NextBio Bioset overlap with KO Atlas from 2,856 DEGs CON-Six1d/d versus CON-Six1+/+ Table S2D: NextBio Bioset over
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899cfcc35f40b45b5ee00d02d229de91
https://doi.org/10.1158/1541-7786.22513372.v1
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6
Endocrine disruption of early uterine differentiation causes adenocarcinoma mediated by Wnt/β-catenin- and PI3K/AKT signaling
Autor: Elizabeth Padilla-Banks, Wendy N. Jefferson, Brian N. Papas, Alisa A. Suen, Xin Xu, Diana V. Carreon, Cynthia J. Willson, Erin M. Quist, Carmen J. Williams
Developmental exposure to non-mutagenic environmental factors can contribute to cancer risk, but the underlying mechanisms are not understood. We used a mouse model of endometrial adenocarcinoma that results from brief developmental exposure to an es
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b07cc08c0253e5823eb6c4aee2191e29
https://doi.org/10.1101/2022.11.18.517135
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7
Multiple tissue-specific epigenetic alterations regulate persistent gene expression changes following developmental DES exposure in mouse reproductive tissues
Autor: Tanner B, Jefferson, Tianyuan, Wang, Wendy N, Jefferson, Yin, Li, Katherine J, Hamilton, Paul A, Wade, Carmen J, Williams, Kenneth S, Korach
Publikováno v: Epigenetics. 18
Clinically, developmental exposure to the endocrine disrupting chemical, diethylstilboestrol (DES), results in long-term male and female infertility. Experimentally, developmental exposure to DES results in abnormal reproductive tract phenotypes in m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3efa74e42987f99bfb23153e1fa1e7e4
https://doi.org/10.1080/15592294.2022.2139986
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8
Akademický článek
Bisphenol A exposure alters developmental gene expression in the fetal rhesus macaque uterus.
Autor: Kathryn C Calhoun, Elizabeth Padilla-Banks, Wendy N Jefferson, Liwen Liu, Kevin E Gerrish, Steven L Young, Charles E Wood, Patricia A Hunt, Catherine A Vandevoort, Carmen J Williams
Publikováno v: PLoS ONE, Vol 9, Iss 1, p e85894 (2014)
Bisphenol A (BPA) exposure results in numerous developmental and functional abnormalities in reproductive organs in rodent models, but limited data are available regarding BPA effects in the primate uterus. To determine if maternal oral BPA exposure
Externí odkaz: https://doaj.org/article/8eb3df61df2e415f8674ea99c3cac588
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9
Uterine Patterning, Endometrial Gland Development, and Implantation Failure in Mice Exposed Neonatally to Genistein
Autor: Sharon M. Zeldin, Alisa A. Suen, Carmen J. Williams, Elizabeth Padilla-Banks, Wendy N. Jefferson, Lindsey J. Royer, Ripla Arora
Publikováno v: Environmental Health Perspectives
Background: Embryo implantation relies on precise hormonal regulation, associated gene expression changes, and appropriate female reproductive tract tissue architecture. Female mice exposed neonatally to the phytoestrogen genistein (GEN) at doses sim
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de486d1691e370ef9ade044f781a5b28
https://doi.org/10.1289/ehp6336
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10
Differentiation Patterns of Uterine Carcinomas and Precursor Lesions Induced by Neonatal Estrogen Exposure in Mice
Autor: Alisa A. Suen, Charles E. Wood, Carmen J. Williams, Wendy N. Jefferson
Publikováno v: Toxicologic Pathology. 46:574-596
Developmental exposure to estrogenic chemicals is an established risk factor for cancer of the female reproductive tract. This increase in risk has been associated with disruption of normal patterns of cellular differentiation during critical stages
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f80a925d0a1275210d1aa0e0313eb9
https://doi.org/10.1177/0192623318779326
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