Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Wendy M. Campana"'
Autor:
Steven L Gonias, Wendy M Campana
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 2, Pp 325-326 (2023)
Externí odkaz:
https://doaj.org/article/4eeb397eb25249c3b9e4f5f45ff30287
Autor:
Stefano Martellucci, Seiji Ohtori, Naoya Hirosawa, Steven L. Gonias, Jasmine Le, Donald P. Pizzo, Mahrou Sadri, Hyo Jun Kwon, Haylie Romero, Wendy M. Campana
Schwann cells (SCs) are known to produce extracellular vesicles (EV) that participate in cell-cell communication by transferring cargo to target cells, including mRNAs, microRNAs, and biologically active proteins. Herein, we report a novel mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0089b83c2fda597cd9b63c729f119447
http://hdl.handle.net/11573/1579990
http://hdl.handle.net/11573/1579990
Autor:
Zixuan Wang, Stefano Martellucci, Alicia Van Enoo, Dana Austin, Cohava Gelber, Wendy M. Campana
Publikováno v:
FASEB J
SP16 is an innovative peptide derived from the carboxyl-terminus of α1-Antitrypsin (AAT), corresponding to residues 364–380, and contains recognition sequences for the low-density lipoprotein receptor-related protein-1 (LRP1). LRP1 is an endocytic
Autor:
Steven L. Gonias, Michael A. Banki, Pardis Azmoon, Haylie K. Romero, Christina J. Sigurdson, Elisabetta Mantuano, Wendy M. Campana
Publikováno v:
The Journal of biological chemistry. 298(3)
Exosomes and other extracellular vesicles (EVs) participate in cell-cell communication. Herein, we isolated EVs from human plasma and demonstrated that these EVs activate cell signaling and promote neurite outgrowth in PC-12 cells. Analysis of human
Autor:
Wendy M. Campana, Chanond A Nasamran, Seiji Ohtori, Alysson R. Muotri, Jacob J. Jeziorski, Steven L. Gonias, Akina Shiga, Coralie Brifault, Pinar Mesci, HyoJun Kwon, Yasuhiro Shiga, John H. Kim
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific reports, vol 9, iss 1
Scientific Reports
Scientific reports, vol 9, iss 1
Scientific Reports
The goal of stem cell therapy for spinal cord injury (SCI) is to restore motor function without exacerbating pain. Induced pluripotent stem cells (iPSC) may be administered by autologous transplantation, avoiding immunologic challenges. Identifying s
Autor:
Wendy M. Campana, Michael A. Banki, Christina J. Sigurdson, Steven L. Gonias, Elisabetta Mantuano, Pardis Azmoon
Publikováno v:
J Immunol
Nonpathogenic cellular prion protein (PrPC) demonstrates anti-inflammatory activity; however, the responsible mechanisms are incompletely defined. PrPC exists as a GPI-anchored membrane protein in diverse cells; however, PrPC may be released from cel
Publikováno v:
Glia
Following injury to the peripheral nervous system (PNS), microglia in the spinal dorsal horn (SDH) become activated and contribute to the development of local neuro-inflammation, which may regulate neuropathic pain processing. The molecular mechanism
Autor:
Yi Ye, M. Danilo Boada, Malvin N. Janal, Nicole N. Scheff, Wendy M. Campana, Aditi Bhattacharya, Elizabeth Salvo, Brian L. Schmidt, Hyesung Kim, Se Hee Jeong, Ian M. Wall, Robert E. Schmidt, John C. Dolan, Susanna Zhang, Angie K. Wu, Donna G. Albertson, Cheng Liu, Tu Huu Nguyen
Publikováno v:
Pain
Cancer invading into nerves, termed perineural invasion (PNI), is associated with pain. Here, we show that oral cancer patients with PNI report greater spontaneous pain and mechanical allodynia compared with patients without PNI, suggesting that uniq
Autor:
Wendy M. Campana, Chanond A Nasamran, Pardis Azmoon, Donald P. Pizzo, Coralie Brifault, Haylie Romero, HyoJun Kwon, Alicia Van-Enoo, Steven L. Gonias
Publikováno v:
J Neurosci
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 40, iss 47
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 40, iss 47
Abnormalities in interactions between sensory neurons and Schwann cells (SCs) may result in heightened pain processing and chronic pain states. We previously reported that SCs express the NMDA receptor (NMDA-R), which activates cell signaling in resp
Autor:
Robert Regestam, Wendy M. Campana, Gunnar Poplawski, Tetsuhiro Ishikawa, Seiji Ohtori, HyoJun Kwon, Kenneth Henry, Yasuhiro Shiga, Steven L. Gonias, Coralie Brifault, Corinne A. Lee-Kubli
Publikováno v:
Glia. 66:1577-1590
Sensory neurons in the PNS demonstrate substantial capacity for regeneration following injury. Recent studies have identified changes in the transcriptome of sensory neurons, which are instrumental for axon regeneration. The role of Schwann cells (SC