Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Wendy Lai"'
Autor:
Kari Ann Shirey, Wendy Lai, Lindsey J Brown, Jorge C G Blanco, Robert Beadenkopf, Yajing Wang, Stefanie N Vogel, Greg A Snyder
Publikováno v:
Innate Immunity, Vol 26 (2020)
TLRs are a family of PRRs that respond to PAMPs or host-derived Danger-Associated Molecular Patterns (DAMPs) to initiate host inflammation and immune responses. TLR dimerization and recruitment of adapter molecules is critical for intracellular signa
Externí odkaz:
https://doaj.org/article/e8c8f57a4e2b417bb920ccf0d3a1949e
Autor:
Kari Ann Shirey, Darren J. Perkins, Wendy Lai, Wei Zhang, Lurds R. Fernando, Fabian Gusovsky, Jorge C. G. Blanco, Stefanie N. Vogel
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT We previously reported that the Toll-like receptor 4 (TLR4) antagonist Eritoran blocks acute lung injury (ALI) therapeutically in mouse and cotton rat models of influenza. However, secondary (2°) bacterial infection following influenza viru
Externí odkaz:
https://doaj.org/article/d53eb0ce4dd8466f9c6dd00fde7aaa19
A Decoy Peptide that Disrupts TIRAP Recruitment to TLRs Is Protective in a Murine Model of Influenza
Autor:
Wenji Piao, Kari Ann Shirey, Lisa W. Ru, Wendy Lai, Henryk Szmacinski, Greg A. Snyder, Eric J. Sundberg, Joseph R. Lakowicz, Stefanie N. Vogel, Vladimir Y. Toshchakov
Publikováno v:
Cell Reports, Vol 11, Iss 12, Pp 1941-1952 (2015)
Toll-like receptors (TLRs) activate distinct, yet overlapping sets of signaling molecules, leading to inflammatory responses to pathogens. Toll/interleukin-1 receptor (TIR) domains, present in all TLRs and TLR adapters, mediate protein interactions d
Externí odkaz:
https://doaj.org/article/63d2963337ed483eb598fd123302073d
Publikováno v:
PLoS Pathogens, Vol 9, Iss 7, p e1003479 (2013)
The cell surface/endosomal Toll-like Receptors (TLRs) are instrumental in initiating immune responses to both bacteria and viruses. With the exception of TLR2, all TLRs and cytosolic RIG-I-like receptors (RLRs) with known virus-derived ligands induce
Externí odkaz:
https://doaj.org/article/624752742ea14c8f843af5a374f78d6d
Autor:
Kari Ann Shirey, Wendy Lai, Mary E Sunday, Frank Cuttitta, Jorge C.G. Blanco, Stefanie N. Vogel
Publikováno v:
Mucosal Immunology.
Autor:
Greg A Snyder, Wendy Lai, Lindsey Brown, Jorge Blanco, Robert Beadenkpf, Yajing wang, Stefanie Vogel, Kari Ann Shirey
Publikováno v:
The Journal of Immunology. 204:226.7-226.7
TIR domain containing proteins are important immune associated proteins shared among Toll-like and interleukin-1/18 receptor family members. In a recent discovery select bacterial, plant and human TIR proteins exhibit enzymatic activity in binding an
A 25-year-old woman who is handcuffed was brought to the emergency department in the custody of police officers. She has type 1 diabetes and last took her insulin over a day ago. She is slurring her words and appears fatigued. She asks if her sugar c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98615ec1091473f6383d7dc031ff193a
https://europepmc.org/articles/PMC5135495/
https://europepmc.org/articles/PMC5135495/
Autor:
Robert J. Hopkin, Alan P. Kenny, Meredith E. Tabangin, Jareen Meinzen-Derr, Koryse Woodrooffe, James MGreenberg, Wendy Lai, Eric S. Hall
Publikováno v:
Journal of Neonatal Biology.
The first trimester fetal foregut generates organs from larynx to ligament of Treitz. The incidence and clinical impact of many of the 29 congenital malformations arising from the foregut organs remain under characterized. We performed a retrospectiv
Autor:
Wendy Lai
I recently returned from eastern Democratic Republic of Congo, where I was working for Medecins Sans Frontieres. And everyone asks, what was it like? It's hard to describe the experience properly. I was 1 of 6 doctors (the other 5 were Congolese) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12181bf3b4f62c9827dada317501aad0
https://europepmc.org/articles/PMC2228355/
https://europepmc.org/articles/PMC2228355/