Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Wendy L. Kimber"'
Autor:
Alexei A Sharov, Yulan Piao, Ryo Matoba, Dawood B Dudekula, Yong Qian, Vincent VanBuren, Geppino Falco, Patrick R Martin, Carole A Stagg, Uwem C Bassey, Yuxia Wang, Mark G Carter, Toshio Hamatani, Kazuhiro Aiba, Hidenori Akutsu, Lioudmila Sharova, Tetsuya S Tanaka, Wendy L Kimber, Toshiyuki Yoshikawa, Saied A Jaradat, Serafino Pantano, Ramaiah Nagaraja, Kenneth R Boheler, Dennis Taub, Richard J Hodes, Dan L Longo, David Schlessinger, Jonathan Keller, Emily Klotz, Garnett Kelsoe, Akihiro Umezawa, Angelo L Vescovi, Janet Rossant, Tilo Kunath, Brigid L M Hogan, Anna Curci, Michele D'Urso, Janet Kelso, Winston Hide, Minoru S H Ko
Publikováno v:
PLoS Biology, Vol 1, Iss 3, p E74 (2003)
Understanding and harnessing cellular potency are fundamental in biology and are also critical to the future therapeutic use of stem cells. Transcriptome analysis of these pluripotent cells is a first step towards such goals. Starting with sources th
Externí odkaz:
https://doaj.org/article/1708d315f6714b659334ba91f551e95e
Autor:
Carole A. Stagg, Takashi Yokota, Saied A. Jaradat, Janet Rossant, Tilo Kunath, Masayuki Usuda, Wendy L. Kimber, Tetsuya S. Tanaka, Minoru S.H. Ko, Hitoshi Niwa
Publikováno v:
Genome Research. 12:1921-1928
Large-scale gene expression profiling was performed on embryo-derived stem cell lines to identify molecular signatures of pluripotency and lineage specificity. Analysis of pluripotent embryonic stem (ES) cells, extraembryonic-restricted trophoblast s
Autor:
Paul Dickinson, Wendy L. Kimber, Fiona M. Kilanowski, Sheila Webb, Barbara J. Stevenson, David J. Porteous, Julia R. Dorin
Publikováno v:
Transgenic Research. 9:55-66
The creation of precise clinical mutations by gene targeting is important in elucidating disease pathogenesis using mouse models. 'Hit and run' gene targeting is an elegant method to achieve this goal. This uses first a positive selection to introduc
Publikováno v:
NeuroReport. 9:793-798
To evaluate the influence of cell type and cationic liposomal formulation on gene transfection efficiency three liposomes (lipofectin, lipofectamine and DOTAP) were used to transfect the human (A172 and MOG-G-CCM) and rodent (C6 and A15A5) glioma cel
Autor:
Chris Ottolenghi, Giuseppe Pilia, Manuela Uda, Jose Elias Garcia, Wendy L. Kimber, Antonio Cao, Antonino Forabosco, David Schlessinger, Laura Crisponi, Manila Deiana
Publikováno v:
Human molecular genetics. 13(11)
FOXL2 mutations cause gonadal dysgenesis or premature ovarian failure (POF) in women, as well as eyelid/forehead dysmorphology in both sexes (the 'blepharophimosis-ptosis-epicanthus inversus syndrome', BPES). Here we report that mice lacking Foxl2 re
Autor:
Minoru S.H. Ko, Michael M. Seidman, Carol Borgmeyer, Alexei A. Sharov, Wendy L. Kimber, Donna Ritter, Nitin Puri
Publikováno v:
Scopus-Elsevier
The advent of microarray technology, coupled with the availability of mouse cDNA collections derived specifically from preimplantation embryos, helps to provide global gene expression profiles for the earliest stages of development. However, to deter
Autor:
Catherine Roberts, Anthony Wynshaw-Boris, Hannah Farmer, Alisoun H. Carey, Helen F. Sutherland, Joshua M. Brickman, Peter J. Scambler, Wendy L. Kimber, Stephanie Halford
Publikováno v:
Molecular and cellular biology. 22(7)
The Hira gene encodes a nuclear WD40 domain protein homologous to the yeast transcriptional corepressors Hir1p and Hir2p. Using targeted mutagenesis we demonstrate that Hira is essential for murine embryogenesis. Analysis of inbred 129Sv embryos carr
Autor:
Michael J. Gambello, Denise M. Larson, Amy Chen, Anthony Wynshaw-Boris, Lisa Garrett, Zoë Weaver, Nardos Lijam, Gabriella Ryan, Carrolee Barlow, Wendy L. Kimber, Shinji Hirotsune, Theresa Hernandez
Publikováno v:
Gene Therapy ISBN: 9783642721625
The use of powerful linkage strategies for the mapping of genetic disease genes has led to the positional cloning of a number of genes associated with human genetic diseases. At the same time, techniques for manipulating the mammalian genome have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2926e493adb196d702b1a3773b80a35
https://doi.org/10.1007/978-3-642-72160-1_3
https://doi.org/10.1007/978-3-642-72160-1_3
Autor:
R Wadey, H O'Donnell, Catherine Taylor, Catherine Roberts, Wendy L. Kimber, Peter J. Scambler, Marie Geneviève Mattei, Anthony Wynshaw-Boris
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 8(5)
Hemizygosity for a region of human Chromosome (Chr) 22q11 has been associated with a wide range of congenital malformation syndromes. The major abnormalities encountered are cardiac defects, dysmorphic facies, T cell dysfunction, clefting, hypocalcem