Telomere and Centromere Staining Followed by M-FISH Improves Diagnosis of Chromosomal Instability and Its Clinical Utility

Autor: Wendy Kerbrat, Annelise Bennaceur-Griscelli, Philippe Voisin, Kevin Soehnlen, Wala Najar, Valentine Marquet, Marguerite Miguet, Andreas Plesch, Claire Borie, William M. Hempel, Nadège Wilhelm-Murer, Catherine Yardin, Anne-Claude Tabet, Noufissa Oudrhiri, Georges Deschenes, Michael Fenech, Bruno Colicchio, Micheline Fontaine Arnoux, Eric Jeandidier, Radhia M'kacher, Catherine Ferrapie, Alain Dieterlen, Theodore Girinsky, Leonhard Heidingsfelder, Patrice Carde, Steffen Junker

Publikováno v: Genes
Volume 11
Issue 5
M’kacher, R, Colicchio, B, Borie, C, Junker, S, Marquet, V, Heidingsfelder, L, Soehnlen, K, Najar, W, Hempel, W M, Oudrhiri, N, Wilhelm-Murer, N, Miguet, M, Arnoux, M, Ferrapie, C, Kerbrat, W, Plesch, A, Dieterlen, A, Girinsky, T, Voisin, P, Deschenes, G, Tabet, A C, Yardin, C, Bennaceur-Griscelli, A, Fenech, M, Carde, P & Jeandidier, E 2020, ' Telomere and centromere staining followed by m-fish improves diagnosis of chromosomal instability and its clinical utility ', Genes, vol. 11, no. 5, 475 . https://doi.org/10.3390/genes11050475
Genes, Vol 11, Iss 475, p 475 (2020)

Dicentric chromosomes are a relevant marker of chromosomal instability. Their appearance is associated with telomere dysfunction, leading to cancer progression and a poor clinical outcome. Here, we present Telomere and Centromere staining followed by

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