Výsledky vyhledávání - "Wendy I, Sligl"

Akademický článek

Antimicrobial stewardship, procalcitonin testing, and rapid blood-culture identification to optimize sepsis care in critically ill adult patients: A quality improvement initiative

Publikováno v: Antimicrobial Stewardship & Healthcare Epidemiology, Vol 3 (2023)

We examined the effect of an antimicrobial stewardship program (ASP), procalcitonin testing and rapid blood-culture identification on hospital mortality in a prospective quality improvement project in critically ill septic adults. Secondarily, we hav

Externí odkaz: https://doaj.org/article/d3b18fd0cafb459ea9885dad6068aea2

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Akademický článek

Predicting in-hospital mortality in pneumonia-associated septic shock patients using a classification and regression tree: a nested cohort study

Autor: Jaime L Speiser, Constantine J Karvellas, Geoffery Shumilak, Wendy I Sligl, Yazdan Mirzanejad, Dave Gurka, Aseem Kumar, Anand Kumar, the Cooperative Antimicrobial Therapy of Septic Shock (CATSS) Database Research Group

Publikováno v: Journal of Intensive Care, Vol 6, Iss 1, Pp 1-10 (2018)

Abstract Background Pneumonia complicated by septic shock is associated with significant morbidity and mortality. Classification and regression tree methodology is an intuitive method for predicting clinical outcomes using binary splits. We aimed to

Externí odkaz: https://doaj.org/article/8d02988cb0864ed3ae14418fce9c3f33

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Erythroid precursors and progenitors suppress adaptive immunity and get invaded by SARS-CoV-2

Autor: Shima Shahbaz, Mohammad Osman, Lai Xu, Olaide Oyegbami, D. Lorne Tyrrell, Shokrollah Elahi, Wendy I Sligl, Justin Shields, Michael A. Joyce

Publikováno v: Stem Cell Reports

SARS-CoV-2 infection is associated with lower blood oxygen levels, even in patients without hypoxia requiring hospitalization. This discordance illustrates the need for a more unifying explanation as to whether SARS-CoV-2 directly or indirectly affec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34c8f049eadbb85600593c53aea182f
https://doi.org/10.1016/j.stemcr.2021.04.001

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Hyperammonemia syndrome post-lung transplantation: Case series and systematic review of literature

Autor: Bruno Fernando Buzo, Jutta K. Preiksaitis, Kieran Halloran, Jayan Nagendran, Derek R. Townsend, Nathan Zelyas, Wendy I. Sligl

Publikováno v: Transplant infectious disease : an official journal of the Transplantation SocietyREFERENCES.

Hyperammonemia syndrome (HS) is a rare post-transplant complication associated with high morbidity and mortality. Its incidence appears to be higher in lung transplant recipients and its pathophysiology is not well understood. In addition to underlyi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::516e8c67cc5d9c73f5ba03fca693c402
https://pubmed.ncbi.nlm.nih.gov/36039822

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Akademický článek

Epidemiology and Outcomes in Critically Ill Patients with Human Immunodeficiency Virus Infection in the Era of Combination Antiretroviral Therapy

Autor: Shannon L. Turvey, Sean M. Bagshaw, Dean T. Eurich, Wendy I. Sligl

Publikováno v: Canadian Journal of Infectious Diseases and Medical Microbiology, Vol 2017 (2017)

Purpose. The impact of critical illness on survival of HIV-infected patients in the era of antiretroviral therapy remains uncertain. We describe the epidemiology of critical illness in this population and identify predictors of mortality. Materials a

Externí odkaz: https://doaj.org/article/dbfe79b89d9c4ec78817ce24eb4ecc02

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COVID-19 epidemiology in Canada from January to December 2020: the pre-vaccine era

Autor: David Waldner, Duncan Webster, Lynora Saxinger, Jennie Johnstone, Wendy I. Sligl, Robyn A Harrison

Publikováno v: FACETS, Vol 6, Iss 1, Pp 760-822 (2021)

This paper summarizes COVID-19 disease epidemiology in Canada in the pre-vaccine era—from January through to December 2020. Canadian case numbers, risk factors, disease presentations (including severe and critical disease), and outcomes are describ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c231b3cbe20d13529334735681f0561
https://doi.org/10.1139/facets-2021-0029

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Outcomes among critically ill adults with influenza infection

Autor: Lori Zapernick, Nelson Lee, Eitan Aziza, Jocelyn M. Slemko, Stephanie Smith, Wendy I. Sligl

Publikováno v: J Assoc Med Microbiol Infect Dis Can

Influenza infection is a major cause of mortality in critical care units.ata on critically ill adult patients with influenza infection from 2014 to 2019 were retrospectively collected, including mortality and critical care resource utilization. Indep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b85cadae8cc4314345e1865639b84f20
https://europepmc.org/articles/PMC9629264/

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Dysregulation of ACE (Angiotensin-Converting Enzyme)-2 and Renin-Angiotensin Peptides in SARS-CoV-2 Mediated Mortality and End-Organ Injuries

Autor: Matt Munan, Anish Nikhanj, Mahmoud Gheblawi, Marko Poglitsch, Conar R. O’Neil, Franca Del Nonno, Zamaneh Kassiri, Wendy I. Sligl, Erika MacIntyre, Kaiming Wang, Daniele Colombo, Gavin Y. Oudit

Publikováno v: Hypertension (Dallas, Tex. : 1979). 79(2)

ACE (angiotensin-converting enzyme)-2 as the target for SARS-CoV-2 also negatively regulates the renin-angiotensin system. Pathological activation of ADAM17 (A disintegrin and metalloproteinase-17) may potentiate inflammation and diminish ACE2-mediat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5952a655422e3e6ac8cee1208bdddb15
https://pubmed.ncbi.nlm.nih.gov/34844421

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