Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Wendy Elkins"'
Autor:
Jacob Ziontz, Murat Bilgel, Andrea T. Shafer, Abhay Moghekar, Wendy Elkins, Jessica Helphrey, Gabriela Gomez, Danielle June, Michael A. McDonald, Robert F. Dannals, Babak Behnam Azad, Luigi Ferrucci, Dean F. Wong, Susan M. Resnick
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 637-645 (2019)
Abstract Introduction Tau pathology, a hallmark of Alzheimer's disease, is observed in the brains of virtually all individuals over 70 years. Methods Using 18F‐AV‐1451 (18F‐flortaucipir) positron emission tomography, we evaluated tau pathology
Externí odkaz:
https://doaj.org/article/c72b594430654196b0394bb5b1f54f3f
Autor:
Krysti L. Todd, Tessa Brighton, Emily S. Norton, Samuel Schick, Wendy Elkins, Olga Pletnikova, Richard H. Fortinsky, Juan C. Troncoso, Peter J. Molfese, Susan M. Resnick, Joanne C. Conover, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Frontiers in Aging Neuroscience, Vol 9 (2018)
Ventriculomegaly (expansion of the brain’s fluid-filled ventricles), a condition commonly found in the aging brain, results in areas of gliosis where the ependymal cells are replaced with dense astrocytic patches. Loss of ependymal cells would comp
Externí odkaz:
https://doaj.org/article/3497baf2331c4384aae845ef9c87b27e
Autor:
Yang An, Jessica Helphrey, Gabriela Gomez, Christos Davatzikos, Dean F. Wong, Luigi Ferrucci, Wendy Elkins, Murat Bilgel, Susan M. Resnick
Publikováno v:
Alzheimer's & Dementia. 14
Autor:
Luigi Ferrucci, Gabriela Gomez, Wendy Elkins, Dean F. Wong, Yang An, Murat Bilgel, Christos Davatzikos, Susan M. Resnick, Jessica Helphrey
Understanding short-term cognitive decline in relation to Alzheimer's neuroimaging biomarkers in early stages of the development of neuropathology and neurodegeneration will inform participant recruitment and monitoring strategies in clinical trials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e78809d3bad9aac46343559067ef14
https://europepmc.org/articles/PMC6061788/
https://europepmc.org/articles/PMC6061788/
Autor:
Yu-Shiang Su, Joshua Oon Soo Goh, Alexander Tereshchenko, Anna C. McCarrey, Susan M. Resnick, Yong-Jheng Tang, Wendy Elkins
Aging compromises the frontal, striatal, and medial temporal areas of the reward system, impeding accurate value representation and feedback processing critical for decision making. However, substantial variability characterizes age-related effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15dcb6686fdd17de47ae661d30e5f319
https://europepmc.org/articles/PMC5148232/
https://europepmc.org/articles/PMC5148232/
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 28:190-197
White matter hyperintensities are frequently detected on cranial magnetic resonance imaging (MRI) scans of older adults. Given the presumed ischemic contribution to the etiology of these lesions and the posited import of resting brain activity on cog
Autor:
Michael A. Kraut, Wendy Elkins, Abhay Moghekar, Susan M. Resnick, Alan B. Zonderman, Richard O'Brien, Juan C. Troncoso
Publikováno v:
Alzheimer's & Dementia. 8
Background Although magnetic resonance imaging (MRI)-detected white matter disease has been correlated with cognitive decline in the elderly individuals, it is unclear whether white matter disease is primarily responsible for the cognitive deteriorat
Autor:
Susan M. Resnick, Madhav Thambisetty, Luigi Ferrucci, Wendy Elkins, Lori L. Beason-Held, Michael A. Kraut, Alan B. Zonderman
Publikováno v:
Alzheimer's & Dementia. 8
Publikováno v:
Neurobiology of aging. 27(7)
Age-related declines in spatial navigation are well-known in human and non-human species. Studies in non-human species suggest that alteration in hippocampal and other neural circuitry may underlie behavioral deficits associated with aging but little