Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Wendy E. Thomas"'
Publikováno v:
Pathogens, Vol 12, Iss 7, p 941 (2023)
Bacterial adhesion is the first step in the formation of surface biofilms. The number of bacteria that bind to a surface from the solution depends on how many bacteria can reach the surface (bacterial transport) and the strength of interactions betwe
Externí odkaz:
https://doaj.org/article/910524a12d974c3086e27d26c1a2cbc8
Autor:
Laura A. Carlucci, Wendy E. Thomas
Publikováno v:
Biophysical Reports, Vol 1, Iss 2, Pp 100031- (2021)
Three-dimensional particle tracking is a routine experimental procedure for various biophysical applications including magnetic tweezers. A common method for tracking the axial position of particles involves the analysis of diffraction rings whose pa
Externí odkaz:
https://doaj.org/article/7344a2dc7b0a4651ba28d2dce0794ec0
Autor:
Keith C. Johnson, Emilie Clemmens, Hani Mahmoud, Robin Kirkpatrick, Juan C. Vizcarra, Wendy E. Thomas
Publikováno v:
Journal of Biological Engineering, Vol 11, Iss 1, Pp 1-13 (2017)
Abstract Background In the past two decades, methods have been developed to measure the mechanical properties of single biomolecules. One of these methods, Magnetic tweezers, is amenable to acquisition of data on many single molecules simultaneously,
Externí odkaz:
https://doaj.org/article/4e180e69dcec4a9ea124b942c69a649b
Autor:
Nathan J. Sniadecki, Sangyoon J. Han, Moritz Stolla, Kevin M. Beussman, John Hocter, Ashley F. Emery, Wendy E. Thomas, Zizhen Song, Molly Y. Mollica, Andrea Leonard, Jeffrey Miles
Measuring the traction forces produced by cells provides insight into their behavior and physiological function. Here, we developed a technique (dubbed ‘black dots’) that microcontact prints a fluorescent micropattern onto a flexible substrate to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae3e77aa1941d756301b9793838567a2
https://doi.org/10.1101/2021.08.02.454500
https://doi.org/10.1101/2021.08.02.454500
Autor:
Evgeni V, Sokurenko, Veronika, Tchesnokova, Gianluca, Interlandi, Rachel, Klevit, Wendy E, Thomas
Publikováno v:
J Mol Biol
Allosteric proteins transition between 'inactive' and 'active' states. In general, such proteins assume distinct conformational states at the level of secondary, tertiary and/or quaternary structure. Different conformers of an allosteric protein can
Autor:
Wendy E Thomas, Laura Carlucci, Olga Yakovenko, Gianluca Interlandi, Isolde Le Trong, Pavel Aprikian, Pearl Magala, Lydia Larson, Yulia Sledneva, Veronika Tchesnokova, Ronald E. Stenkamp, Evgeni V. Sokurenko
Publikováno v:
J Mol Biol
The FimH protein of Escherichia coli is a model two-domain adhesin that is able to mediate an allosteric catch bond mechanism of bacterial cell attachment, where the mannose-binding lectin domain switches from an ‘inactive’ conformation with fast
Autor:
Sangyoon J. Han, Molly Y. Mollica, Wendy E. Thomas, Kevin M. Beussman, John Hocter, Andrea Leonard, Ashley F. Emery, Moritz Stolla, Jeffrey Miles, Nathan J. Sniadecki, Zizhen Song
Publikováno v:
Acta biomaterialia.
Measuring the traction forces produced by cells provides insight into their behavior and physiological function. Here, we developed a technique (dubbed ‘black dots’) that microcontact prints a fluorescent micropattern onto a flexible substrate to
Autor:
Susan L. Fink, Michael Gale, Olga Yakovenko, Michael Davis, Andreas B. den Hartigh, Christian Lood, Wendy E. Thomas, Marian R. Fairgrieve, Bhargavi Duvvuri
Publikováno v:
Proceedings of the National Academy of Sciences. 116:5061-5070
Pyroptosis is an inflammatory form of programmed cell death following cellular damage or infection. It is a lytic process driven by gasdermin D-mediated cellular permeabilization and presumed osmotic forces thought to induce swelling and rupture. We
Autor:
Hovhannes Avagyan, Rachel E. Klevit, Laura A. Carlucci, Evgeni V. Sokurenko, Benjamin Basanta, Dagmara I. Kisiela, Angelo Ramos, Wendy E. Thomas, Ronald E. Stenkamp, Pearl Magala, Veronika Tchesnokova, Vladimir Yarov-Yarovoy, Anahit Hovhannisyan, Gianluca Interlandi
Publikováno v:
PLoS pathogens, vol 17, iss 4
PLoS Pathogens, Vol 17, Iss 4, p e1009440 (2021)
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 4, p e1009440 (2021)
PLoS Pathogens
Critical molecular events that control conformational transitions in most allosteric proteins are ill-defined. The mannose-specific FimH protein of Escherichia coli is a prototypic bacterial adhesin that switches from an ‘inactive’ low-affinity s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76213e01c3c0afb912f1ba322843b6b0
https://escholarship.org/uc/item/0j29f4b5
https://escholarship.org/uc/item/0j29f4b5
Autor:
Shivani Gupta Ludwig, Casey L. Kiyohara, Laura A. Carlucci, Wendy E. Thomas, Dagmara I. Kisiela, Evgeni V. Sokurenko
Publikováno v:
Journal of Biological Engineering
Journal of Biological Engineering, Vol 15, Iss 1, Pp 1-12 (2021)
Journal of Biological Engineering, Vol 15, Iss 1, Pp 1-12 (2021)
BackgroundRecognition proteins are critical in many biotechnology applications and would be even more useful if their binding could be regulated. The current gold standard for recognition molecules, antibodies, lacks convenient regulation. Alternativ