Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Wendy C. Sheu"'
Autor:
Zhang Ye, Wendy C. Sheu, Huan Qu, Bin Peng, Jia Liu, Li Zhang, Fanen Yuan, Yuxin Wei, Jiangbing Zhou, Qianxue Chen, Xuan Xiao, Shenqi Zhang
Publikováno v:
Small Science, Vol 4, Iss 8, Pp n/a-n/a (2024)
Glioblastoma multiforme (GBM) is a formidable cancer to treat due to the lack of effective drugs that can also efficiently cross the blood–brain barrier (BBB). Herein, a novel strategy involving the synthesis of p28 peptide‐conjugated, lexiscan (
Externí odkaz:
https://doaj.org/article/d6256e15869649e394129400758c6cb9
Autor:
Shenqi Zhang, Bin Peng, Zeming Chen, Jiang Yu, Gang Deng, Youmei Bao, Chao Ma, Fengyi Du, Wendy C. Sheu, W. Taylor Kimberly, J. Marc Simard, Daniel Coman, Qianxue Chen, Fahmeed Hyder, Jiangbing Zhou, Kevin N. Sheth
Publikováno v:
Bioactive Materials, Vol 16, Iss , Pp 57-65 (2022)
Stroke is the leading cause of death and disability. Currently, there is no effective pharmacological treatment for this disease, which can be partially attributed to the inability to efficiently deliver therapeutics to the brain. Here we report the
Externí odkaz:
https://doaj.org/article/b2d82bb2d70f483b9966733478e29137
Autor:
Jun Liu, Xiaoying Wang, Ann T. Chen, Xingchun Gao, Benjamin T. Himes, Hongyi Zhang, Zeming Chen, Jianhui Wang, Wendy C. Sheu, Gang Deng, Yang Xiao, Pan Zou, Shenqi Zhang, Fuyao Liu, Yong Zhu, Rong Fan, Toral R. Patel, W. Mark Saltzman, Jiangbing Zhou
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Improved treatment of glioblastoma (GBM) can be achieved by inducing differentiation of glioblastoma stem cells (GSCs). Here, the authors show that zinc finger protein 117 (ZNF117) is a regulator of GSC differentiation via Notch signaling through int
Externí odkaz:
https://doaj.org/article/45a610fac96344a087a5f202c74fb20b
Autor:
Yu Zhou, Shenqi Zhang, Zeming Chen, Youmei Bao, Ann T. Chen, Wendy C. Sheu, Fuyao Liu, Zhaozhong Jiang, Jiangbing Zhou
Publikováno v:
Advanced Science, Vol 7, Iss 5, Pp n/a-n/a (2020)
Abstract Breast cancer brain metastases (BCBM) is a devastating disease with dismal prognosis. Although chemotherapy is widely used for clinical management of most tumors, it is often ineffective for BCBM. Therefore, alternative approaches for improv
Externí odkaz:
https://doaj.org/article/bd229033568541c4bdd7941c6835f812
Autor:
Junning Ma, Miao Li, Haijun Wang, Jun Liu, Zhiyong Zou, Ying Xie, Yuwen Zhu, Hui Xu, Youmei Bao, Wendy C. Sheu, Shenqi Zhang, Jiangbing Zhou, Longbo Zhang, Haoan Wu, Xue Zhang, Zhouqi Meng, Fuyao Liu, Ann T. Chen
Publikováno v:
Nano Letters. 20:4084-4094
Nanoparticle (NP)-based cancer immunotherapy has been extensively explored. However, the efficacy of existing strategies is often limited by the lack of effective tumor-specific antigens or the inability to present costimulatory signal or both. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39a349cdbbf11ba916afa1867cb333c
https://doi.org/10.1021/acs.nanolett.9b05171
https://doi.org/10.1021/acs.nanolett.9b05171
Autor:
Shenqi Zhang, Bin Peng, Zeming Chen, Jiang Yu, Gang Deng, Youmei Bao, Chao Ma, Fengyi Du, Wendy C. Sheu, W. Taylor Kimberly, J. Marc Simard, Daniel Coman, Qianxue Chen, Fahmeed Hyder, Jiangbing Zhou, Kevin N. Sheth
Publikováno v:
Bioactive materials. 16
Stroke is the leading cause of death and disability. Currently, there is no effective pharmacological treatment for this disease, which can be partially attributed to the inability to efficiently deliver therapeutics to the brain. Here we report the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7282d627b8f3e957045572d55403c8e1
https://pubmed.ncbi.nlm.nih.gov/35386312
https://pubmed.ncbi.nlm.nih.gov/35386312
Autor:
Ann T Chen, Yang Xiao, Xiangjun Tang, Mehdi Baqri, Xingchun Gao, Melanie Reschke, Wendy C Sheu, Gretchen Long, Yu Zhou, Gang Deng, Shenqi Zhang, Yanxiang Deng, Zhiliang Bai, Dongjoo Kim, Anita Huttner, Russell Kunes, Murat Günel, Jennifer Moliterno, W Mark Saltzman, Rong Fan, Jiangbing Zhou
Publikováno v:
Neuro-oncology.
Background Improved treatment of glioblastoma (GBM) needs to address tumor invasion, a hallmark of the disease that remains poorly understood. In this study, we profiled GBM invasion through integrative analysis of histological and single-cell RNA se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd4a0aa2a26bf9bc4ecb47f170fac75
https://pubmed.ncbi.nlm.nih.gov/35901838
https://pubmed.ncbi.nlm.nih.gov/35901838
Autor:
Jun Liu, Xiaoying Wang, Ann T. Chen, Xingchun Gao, Benjamin T. Himes, Hongyi Zhang, Zeming Chen, Jianhui Wang, Wendy C. Sheu, Gang Deng, Yang Xiao, Pan Zou, Shenqi Zhang, Fuyao Liu, Yong Zhu, Rong Fan, Toral R. Patel, W. Mark Saltzman, Jiangbing Zhou
Publikováno v:
Nature communications. 13(1)
Glioblastoma (GBM) is a deadly disease without effective treatment. Because glioblastoma stem cells (GSCs) contribute to tumor resistance and recurrence, improved treatment of GBM can be achieved by eliminating GSCs through inducing their differentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf4e91878b5821f39e446b4d28333dd
https://pubmed.ncbi.nlm.nih.gov/35459228
https://pubmed.ncbi.nlm.nih.gov/35459228
Autor:
Fuyao Liu, Bin Peng, Miao Li, Junning Ma, Gang Deng, Shenqi Zhang, Wendy C. Sheu, Pan Zou, Haoan Wu, Jun Liu, Ann T. Chen, Farrah S. Mohammed, Jiangbing Zhou
Publikováno v:
Cell Reports Physical Science. 3:100691
Despite being effective for many other solid tumors, traditional anti-angiogenic therapy has been shown to be insufficient for the treatment of malignant glioma. Here, we report the development of polyphenol nanoparticles (NPs), which not only inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::151c4e59dcda98958f5b4f5cbe66b227
https://doi.org/10.1016/j.xcrp.2021.100691
https://doi.org/10.1016/j.xcrp.2021.100691
Autor:
Arindam Raj, Michelle J Wu, Shuozhen Bao, Ryan Nguyen, Tiffany H Tseng, Mengqing Xu, Themis R. Kyriakides, Farrah Shalima Mohammed, Saiti S Halder, Wendy C. Sheu, Hugh Xiao
Publikováno v:
Biomed Mater
Nanomaterials (NMs) have revolutionized multiple aspects of medicine by enabling novel sensing, diagnostic, and therapeutic approaches. Advancements in processing and fabrication have also allowed significant expansion in the applications of the majo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::545a18b086694d625f660fe181c9a72d
https://doi.org/10.1088/1748-605x/abe5fa
https://doi.org/10.1088/1748-605x/abe5fa