Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Wendy C. Brown"'
Autor:
Gina M. Gallego-Lopez, Audrey O. T. Lau, Wendy C. Brown, Wendell C. Johnson, Massaro W. Ueti, Carlos E. Suarez
Publikováno v:
Parasites & Vectors, Vol 11, Iss 1, Pp 1-8 (2018)
Abstract Background Bovine babesiosis caused by Babesia bovis is a tick-borne hemoparasitic disease of global impact, and improved control is needed. In B. bovis, spherical body protein 2 (SBP-2) truncated copies 7, 9 and 11 (sbp2t7, sbp2t9 and sbp2t
Externí odkaz:
https://doaj.org/article/8064a8e3d5514e32835746e9bd7ae6fa
Autor:
Bing Zhang, Antonio S. Cavallaro, Karishma T. Mody, Jun Zhang, James R. Deringer, Wendy C. Brown, Timothy J. Mahony, Chengzhong Yu, Neena Mitter
Publikováno v:
Nanomaterials, Vol 6, Iss 11, p 201 (2016)
Bovine anaplasmosis or cattle-tick fever is a tick-borne haemolytic disease caused by the rickettsial haemoparasite Anaplasma marginale in tropical and subtropical areas of the world. While difficult to express, the proteins VirB9-1 and VirB10 are im
Externí odkaz:
https://doaj.org/article/144ad1835372471192a37b5982abfaee
Autor:
Wendell C. Johnson, Carlos E. Suarez, Wendy C. Brown, Massaro W. Ueti, Audrey O.T. Lau, Gina M Gallego-Lopez
Publikováno v:
Parasites & Vectors, Vol 11, Iss 1, Pp 1-8 (2018)
Parasites & Vectors
Parasites & Vectors
Background Bovine babesiosis caused by Babesia bovis is a tick-borne hemoparasitic disease of global impact, and improved control is needed. In B. bovis, spherical body protein 2 (SBP-2) truncated copies 7, 9 and 11 (sbp2t7, sbp2t9 and sbp2t11) gene
Autor:
John P. Bannantine, Maria Clara D. Cardieri, J.R. Deringer, Meaghan Veronica Eren, Julianne K. Hwang, Gaber S. Abdellrazeq, Wendy C. Brown, M.G. Norton, William C. Davis, Parissa Ziaei, Cleverson D. Souza, Elizabeth I. Laws
Publikováno v:
Journal of Applied Microbiology. 123:54-65
Aims We evaluated the potential of a nanoparticle (NP) delivery system to improve methods of delivery of candidate peptide-based vaccines for Paratuberculosis in cattle. Methods and Results Peptides derived from Mycobacterium avium subsp. paratubercu
Segmental Variation in a Duplicated msp2 Pseudogene Generates Anaplasma marginale Antigenic Variants
Autor:
Telmo Graça, Pei-Shin Ku, G. Kenitra Hammac, Wendy C. Brown, Joshua E. Turse, Marta G. Silva, Kelly A. Brayton, Guy H. Palmer
Anaplasma marginale is a prototypical highly antigenically variant bacterial pathogen dependent on the sequential generation of major surface protein 2 (Msp2) outer membrane variants to establish persistent infection. Msp2 is encoded by a single expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7663bb812f38d6ad7af1ec63d54ed1bc
https://europepmc.org/articles/PMC6346141/
https://europepmc.org/articles/PMC6346141/
Autor:
Poothapillai Kasinathan, Jonathan E. Beever, Ahmed Tibary, Subramaniam Srikumaran, Sudarvili Shanthalingam, Wendy C. Brown
Publikováno v:
Proceedings of the National Academy of Sciences. 113:13186-13190
Signal peptides of membrane proteins are cleaved by signal peptidase once the nascent proteins reach the endoplasmic reticulum. Previously, we reported that, contrary to the paradigm, the signal peptide of ruminant CD18, the β subunit of β2 integri
Autor:
James R. Deringer, Tomohiro Okagawa, Satoru Konnai, Shiro Murata, Glen A. Scoles, Wendy C. Brown, Massaro W. Ueti, Kazuhiko Ohashi
Publikováno v:
Infection and Immunity. 84:2779-2790
The CD4 + T-cell response is central for the control of Anaplasma marginale infection in cattle. However, the infection induces a functional exhaustion of antigen-specific CD4 + T cells in cattle immunized with A. marginale outer membrane proteins or
Autor:
Wendy C. Brown, Anthony F. Barbet
Publikováno v:
Annual Review of Animal Biosciences. 4:177-197
Tick-transmitted gram-negative bacteria in the family Anaplasmataceae in the order Rickettsiales cause persistent infection and morbidity and mortality in ruminants. Whereas Anaplasma marginale infection is restricted to ruminants, Anaplasma phagocyt
Autor:
Glen A. Scoles, Eric L. Sutten, Joshua E. Turse, Wendy C. Brown, Wendell C. Johnson, Paulraj K. Lawrence, James R. Deringer, Junzo Norimine, Sushan Han
Publikováno v:
Clinical and Vaccine Immunology. 22:742-753
We have shown that in cattle previously immunized with outer membrane proteins, infection withAnaplasma marginaleinduces a functionally exhausted CD4 T-cell response to theA. marginaleimmunogen. Furthermore, T-cell responses following infection in no
Autor:
Joshua E. Turse, Wendy C. Brown, Guy H. Palmer, Elkin Gustavo Forero-Becerra, James E. Futse, Massaro W. Ueti, Susan M. Noh, James R. Deringer
Publikováno v:
Clinical and Vaccine Immunology. 24
Within the protective outer membrane (OM) fraction of Anaplasma marginale , several vaccine candidates have emerged, including a family of OM proteins (OMPs) 7 to 9, which share sequence identity with each other and with the single protein OMP7 in th