Výsledky vyhledávání - "Wendy Blanda"

Mechanical testing methods for drug-releasing vaginal rings

Autor: Clare McCoy, Wendy Blanda, Bronagh Millar, Bashir Hansraj, Brid Devlin, R. Karl Malcolm, Diarmaid J. Murphy, Peter Boyd

Publikováno v: McCoy, C F, Millar, B G, Murphy, D J, Blanda, W, Hansraj, B, Devlin, B, Malcolm, R K & Boyd, P 2019, ' Mechanical testing methods for drug-releasing vaginal rings ', International Journal of Pharmaceutics, vol. 559, pp. 182-191 . https://doi.org/10.1016/j.ijpharm.2019.01.026

Vaginal rings (VRs) are currently marketed for contraceptive or hormone regulation purposes, and investigationally, have been widely reported for delivery of antiretrovirals to reduce HIV transmission. To date, there is no national or international s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13beeaa537d59538289e26b920b2849f
https://pure.qub.ac.uk/en/publications/mechanical-testing-methods-for-drugreleasing-vaginal-rings(09e068c9-c24e-4050-b791-e61527d6d9a2).html

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Matrix and reservoir-type multipurpose vaginal rings for controlled release of dapivirine and levonorgestrel

Autor: Ian Major, Brid Devlin, Andrew Brimer, Clare McCoy, Jonathon D. S. Holt, Diarmaid J. Murphy, Susan M. Fetherston, R. Karl Malcolm, Sandeep Kumar, Wendy Blanda, Peter Boyd

Publikováno v: Boyd, P, Fetherston, S M, McCoy, C F, Major, I, Murphy, D J, Kumar, S, Holt, J, Brimer, A, Blanda, W, Devlin, B & Malcolm, R K 2016, ' Matrix and reservoir-type multipurpose vaginal rings for controlled release of dapivirine and levonorgestrel ', International Journal of Pharmaceutics, vol. 511, no. 1, pp. 619-629 . https://doi.org/10.1016/j.ijpharm.2016.07.051

A matrix-type silicone elastomer vaginal ring providing 28-day continuous release of dapivirine (DPV) ⿿ a lead candidate human immunodeficiency virus type 1 (HIV-1) microbicide compound ⿿ has recently demonstrated moderate levels of protection in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5724c1be40fb5bf0655cdf956fd3122f
https://pure.qub.ac.uk/en/publications/matrix-and-reservoirtype-multipurpose-vaginal-rings-for-controlled-release-of-dapivirine-and-levonorgestrel(1c672efb-3a3e-40dc-bd55-f59c37050f55).html

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Development of Reservoir Vaginal Rings Containing Dapivirine or Hormonal Contraceptive Steroids

Autor: Clare McCoy, Chris Gimour, Jonathon D. S. Holt, Jeremy Nuttall, Diarmaid J. Murphy, Wendy Blanda, Ian Major, Andrew Brimer, Tiffany Derrick, Brid Devlin, Peter Boyd, Karl Malcolm, Susan M. Fetherston

Publikováno v: AIDS Research and Human Retroviruses. 30:A68-A68

Background: By extending the use duration of vaginal rings (VRs) the overall production cost per patient per month can be greatly reduced. Matrix-type ring designs produce an initial burst of drug release and concentrations during the burst must be m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0121146545e42ddf55b4b6e671121671
https://doi.org/10.1089/aid.2014.5124.abstract

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Evaluation of the Factors Contributing to Levonorgestrel Binding in Addition Cure Silicone Elastomer Vaginal Rings

Autor: Karl Malcolm, Diarmaid Murphy, Clare McCoy, Peter Boyd, Sandeep Kumar, Susan Fetherston, Andrew Brimer, Jonathon Holt, Wendy Blanda, Brid Devlin, Jeremy Nuttall, Chris Gilmour, Tiffany Derrick

Publikováno v: Queen's University Belfast-PURE
Malcolm, K, Murphy, D, McCoy, C, Boyd, P, Kumar, S, Fetherston, S, Brimer, A, Holt, J, Blanda, W, Devlin, B, Nuttall, J, Gilmour, C & Derrick, T 2014, ' Evaluation of the Factors Contributing to Levonorgestrel Binding in Addition Cure Silicone Elastomer Vaginal Rings ' HIV R4P-HIV Research for Prevention, Cape Town, South Africa, 28/10/2014-31/10/2014, .

Background: Following progress of the dapivirine (DPV)-releasing silicone elastomer (SE) vaginal ring (VR) into Phase III clinical studies, there is now interest in developing next-generation rings that additionally provide contraception. Levonorgest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::44c05628008bd6af3249d626510c25d0
https://pure.qub.ac.uk/en/publications/e269156f-9a76-4f16-96d8-7ec05bafa579

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Thermal properties and eutectic behaviour of dapivirine in combination with steroid hormones and other antiretrovirals

Autor: Karl Malcolm, Clare McCoy, Diarmaid Murphy, Peter Boyd, Sandeep Kumar, Susan Fetherston, Andrew Brimer, Jonathon Holt, Brid Devlin, Wendy Blanda, Jeremy Nuttall, Chris Gilmour

Publikováno v: Queen's University Belfast-PURE
Malcolm, K, McCoy, C, Murphy, D, Boyd, P, Kumar, S, Fetherston, S, Brimer, A, Holt, J, Devlin, B, Blanda, W, Nuttall, J & Gilmour, C 2014, ' Thermal properties and eutectic behaviour of dapivirine in combination with steroid hormones and other antiretrovirals ' HIV R4P-HIV Research for Prevention, Cape Town, South Africa, 28/10/2014-31/10/2014, .

Background: Combination drug products can display thermal behaviour that is more complex than for the corresponding single drug products. For example, the contraceptive vaginal ring (VR) Nuvaring contains a eutectic (lowest melting) composition of et

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::171fe3c99145b804a08103b95a0731cf
https://pure.qub.ac.uk/en/publications/14cfe93f-1f00-4020-abce-1937e3ba4f5b

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