Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Wendy B. Bernstein"'
Autor:
Jaidyn Muhandiramge, Erica T. Warner, John R. Zalcberg, Andrew Haydon, Galina Polekhina, Gijsberta J. van Londen, Peter Gibbs, Wendy B. Bernstein, Jeanne Tie, Jeremy L. Millar, Victoria J. Mar, John J. McNeil, Robyn L. Woods, Suzanne G. Orchard
Publikováno v:
Cancers
Volume 15
Issue 4
Pages: 1017
Volume 15
Issue 4
Pages: 1017
Introduction: Cancer treatment planning in older adults is complex and requires careful balancing of survival, quality of life benefits, and risk of treatment-related morbidity and toxicity. As a result, treatment selection in this cohort tends to di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52c97e831adba71a2430d26bf3a443a
https://doi.org/10.3390/cancers15041017
https://doi.org/10.3390/cancers15041017
Autor:
Wendy B. Bernstein
Cancer is a significant health care challenge in the tropics. GLOBOCAN 2018 estimates 18.1 million new cases and 9.6 million deaths from cancer in 2018. While the majority of incident cases occur in high and very high income nations, 70% of the death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89dbf8bff00e2d11f2438e898164389a
https://doi.org/10.1016/b978-0-323-55512-8.00023-5
https://doi.org/10.1016/b978-0-323-55512-8.00023-5
Autor:
Naomi E Aronson, Glenn W Wortmann, William R Byrne, Robin S Howard, Wendy B Bernstein, Mary A Marovich, Mark E Polhemus, In-Kyu Yoon, Kelly A Hummer, Robert A Gasser, Charles N Oster, Paul M Benson
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 3, p e628 (2010)
BackgroundCutaneous Leishmania major has affected many travelers including military personnel in Iraq and Afghanistan. Optimal treatment for this localized infection has not been defined, but interestingly the parasite is thermosensitive.Methodology/
Externí odkaz:
https://doaj.org/article/c04558007a874f7c8881f817483cce86
Autor:
William D. Figg, Wendy B. Bernstein, Junji Tsurutani, David J. Liewehr, Gideon M. Blumenthal, Regan M. Memmott, Eva Szabo, Roopa De Chowdhury, Arun Rajan, Seth M. Steinberg, Giuseppe Giaccone, Phillip A. Dennis, Takefumi Komiya, Marc S. Ballas, Guinevere Chun, Cody J. Peer, Shigeru Kawabata
Publikováno v:
Translational lung cancer research. 8(3)
Background: Single-agent pemetrexed is a treatment for recurrent non-squamous non-small cell lung cancer (NSCLC) that provides limited benefit. Preclinical studies showed promising synergistic effects when the mammalian target of rapamycin (mTOR) inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8900a56f4b2854ad0d9ac8c5f6078f4e
https://pubmed.ncbi.nlm.nih.gov/31367538
https://pubmed.ncbi.nlm.nih.gov/31367538
Autor:
Cynthia Helsabeck, Seth M. Steinberg, Takefumi Komiya, William D. Figg, Guinevere Chun, Marc S. Ballas, Wendy B. Bernstein, Roopa DeChowdhury, Jaclyn LoPiccolo, Joell J. Gills, Hyejeong Root, Shigeru Kawabata, Gideon M. Blumenthal, Phillip A. Dennis, Betsy Morrow, Erin R. Gardner
Publikováno v:
Oncotarget
Nelfinavir is an HIV protease inhibitor being repurposed as an anti-cancer agent in preclinical models and in small oncology trials, yet the MTD of nelfinavir has not been determined. Therefore, we conducted a Phase Ia study to establish the maximum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb86410a248249b5df99c6536ef579ee
https://doi.org/10.18632/oncotarget.2415
https://doi.org/10.18632/oncotarget.2415
Autor:
Galina Polekhina, Wendy B. Bernstein, Christopher A. Reid, Finlay A. Macrae, Asad Umar, Anne M. Murray, Raj C. Shah, Jessica E. Lockery, Brenda Kirpach, Andrew T. Chan, Josie van London, Leslie G. Ford, John Zalcberg, Andrew Haydon, Joanne Ryan, Rory Wolfe, John J McNeil, Mark Nelson, Jeanne Tie, Robyn L. Woods, Ellen Richmond, Peter Gibbs, Yin Cao, Suzanne G Orchard
Publikováno v:
Gastroenterology. 156:S-78
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::067e8ea3dca2a7f608fc602eb7fb0b84
https://doi.org/10.1016/s0016-5085(19)36983-5
https://doi.org/10.1016/s0016-5085(19)36983-5
Publikováno v:
JCR: Journal of Clinical Rheumatology. 18:134-137
Hemophagocytic lymphohistiocytosis (HLH) is an immune disorder characterized by cytokine dysregulation and uncontrolled activation of T lymphocytes and macrophages. It is categorized as primary when associated with specific genetic mutations or secon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bccd64cc14186b29b81ff0ed9cbad63
https://doi.org/10.1097/rhu.0b013e31824e8d9b
https://doi.org/10.1097/rhu.0b013e31824e8d9b
Autor:
Wendy B. Bernstein, Phillip A. Dennis
Publikováno v:
Current Opinion in HIV and AIDS. 3:666-675
Although designed to target only the HIV protease, HIV protease inhibitors induce toxicities in patients such as insulin resistance and lipodystrophy that suggest that protease inhibitors have other targets in mammalian cells. Akt controls insulin si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5594a912d419d424e3bd86bd6bd4cb97
https://doi.org/10.1097/coh.0b013e328313915d
https://doi.org/10.1097/coh.0b013e328313915d
Publikováno v:
Drug Resistance Updates. 11:32-50
The PI3K/Akt/mTOR pathway is a prototypic survival pathway that is constitutively activated in many types of cancer. Mechanisms for pathway activation include loss of tumor suppressor PTEN function, amplification or mutation of PI3K, amplification or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da79fde285176327be1e4e43615b112
https://doi.org/10.1016/j.drup.2007.11.003
https://doi.org/10.1016/j.drup.2007.11.003
Publikováno v:
The Journal of Infectious Diseases. 191:2064-2074
Background An assessment of biomarkers from an analysis of human peripheral blood mononuclear cell gene-expression profiles was made, to acquire an understanding of transcriptional changes associated with human immunodeficiency virus type 1 (HIV-1) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca363c156ea10d293af034ec2c3250b
https://doi.org/10.1086/430321
https://doi.org/10.1086/430321