Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Wendy A. Herbst"'
Publikováno v:
The Journal of Cell Biology
Herbst et al. use a novel approach for identifying activity-dependent changes in the nuclear proteome of neurons and provide evidence that regulated degradation of the tumor suppressor protein PDCD4 is required for normal activity-dependent transcrip
Activity-dependent gene expression is critical for synapse development and plasticity. To elucidate novel mechanisms linking neuronal activity to changes in transcription, we compared the nuclear proteomes of tetrodotoxin-silenced and bicuculline-sti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fdf064821bb100887b951ae51c6397f
https://doi.org/10.1101/2021.02.06.429040
https://doi.org/10.1101/2021.02.06.429040
Autor:
Kelsey C. Martin, Wendy A. Herbst
Synapse-to-nucleus communication is essential for neural development, plasticity, and repair. In addition to fast electrochemical signaling, neurons employ a slower mechanism of protein transport from synapse-to-nucleus. This mechanism provides poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8955ac42e5763bdd20597f1af8e4feac
https://escholarship.org/uc/item/4ch621pv
https://escholarship.org/uc/item/4ch621pv
Publikováno v:
The Journal of Comparative Neurology
Calcium activity has been implicated in many neurodevelopmental events, including the specification of neurotransmitter phenotypes. Higher levels of calcium activity lead to an increased number of inhibitory neural phenotypes, whereas lower levels of