Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Wendy A. Boivin"'
Autor:
Wendy A. Boivin, Marlo Shackleford, Amanda Vanden Hoek, Hongyan Zhao, Tillie L. Hackett, Darryl A. Knight, David J. Granville
Publikováno v:
PLoS ONE, Vol 7, Iss 5 (2012)
Externí odkaz:
https://doaj.org/article/e1a876af67cd48ee811ede491a6f8e23
Autor:
Gideon Obasanmi, Matthew R. Zeglinski, Ella Hardie, Anna-Catharina Wilhelm, Christopher T. Turner, Sho Hiroyasu, Wendy A. Boivin, Yuan Tian, Hongyan Zhao, Eleanor To, Jing Z. Cui, Jeanne Xi, Hyung-Suk Yoo, Manjosh Uppal, David J. Granville, Joanne A. Matsubara
Publikováno v:
Laboratory Investigation. 103:100123
Age-related macular degeneration (AMD) is a leading cause of irreversible central vision loss in the elderly. The pathology of neovascular AMD (nAMD), also known as wet AMD, is associated with abnormal blood vessel growth in the eye and involves an i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d40c49420c6f7e36e0bd58a97f0ac2c
https://doi.org/10.1016/j.labinv.2023.100123
https://doi.org/10.1016/j.labinv.2023.100123
Autor:
Thomas Abraham, Wendy A. Boivin, Sara Pazooki, David J. Granville, Paul Hiebert, Hongyan Zhao
Publikováno v:
Experimental Gerontology. 46:489-499
Apolipoprotein E knockout (apoE-KO) mice have been utilized for decades as a model of atherosclerosis. However, in addition to atherosclerosis, apoE-KO mice develop extensive cutaneous xanthomatosis, accelerated skin aging and frailty when fed a high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b34b9345036fd1d69ab9e7824b0380c
https://doi.org/10.1016/j.exger.2011.02.004
https://doi.org/10.1016/j.exger.2011.02.004
Autor:
Wendy A. Boivin, Alon Hendel, Sarah J. Williams, David J. Granville, Lisa S. Ang, Michael F. Allard, Hongyan Zhao, Ciara M. Chamberlain, Dawn Cooper, Maggie Folkesson, Bruce M. McManus, Jesper Swedenborg
Publikováno v:
The American Journal of Pathology; Vol 176
Granzyme B (GZMB) is a serine protease that is abundantly expressed in advanced human atherosclerotic lesions and may contribute to plaque instability. Perforin is a pore-forming protein that facilitates GZMB internalization and the induction of apop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f88113244ce26c6b93bd682bc52938f3
Publikováno v:
Laboratory Investigation; a Journal of Technical Methods and Pathology
The cytotoxic granzyme B (GrB)/perforin pathway has been traditionally viewed as a primary mechanism that is used by cytotoxic lymphocytes to eliminate allogeneic, virally infected and/or transformed cells. Although originally proposed to have intrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb517667049552a25741d8183d03c88
http://europepmc.org/articles/PMC7102238
http://europepmc.org/articles/PMC7102238
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78939 (2013)
PLoS ONE
PLoS ONE
The granzyme B/perforincytotoxic pathway is a well established mechanism of initiating target cell apoptosis. Previous studies have suggested a role for the granzyme B/perforin cytotoxic pathway in vulnerable atherosclerotic plaque formation. In the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e638bb4a90dd30e98cfbe5723891a6b
http://europepmc.org/articles/PMC3811993?pdf=render
http://europepmc.org/articles/PMC3811993?pdf=render
Autor:
Wendy A. Boivin, Marlo Shackleford, Amanda Vanden Hoek, Hongyan Zhao, Tillie L. Hackett, Darryl A. Knight, David J. Granville
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 5 (2012)
PLoS ONE, Vol 7, Iss 5 (2012)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0da63ccb7dacd8c7cde49247dd868a9
http://europepmc.org/articles/PMC3351479
http://europepmc.org/articles/PMC3351479
Autor:
Marlo Shackleford, Amanda L. Vanden Hoek, Darryl A. Knight, Tillie L. Hackett, Hongyan Zhao, Wendy A. Boivin, David J. Granville
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33163 (2012)
PLoS ONE
PLoS ONE
Objective Granzyme B (GrB) is a pro-apoptotic serine protease that contributes to immune-mediated target cell apoptosis. However, during inflammation, GrB accumulates in the extracellular space, retains its activity, and is capable of cleaving extrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a8309f69e0560febb5c81749ca4cc33
http://europepmc.org/articles/PMC3316562?pdf=render
http://europepmc.org/articles/PMC3316562?pdf=render
Publikováno v:
Cell death and differentiation. 17(4)
Chronic inflammation is a hallmark of age-related cardiovascular and pulmonary diseases. Granzymes are a family of serine proteases that have been traditionally viewed as initiators of immune-mediated cell death. However, recent findings suggest that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f45a188bbc46c4ede191c54caff8b97
https://pubmed.ncbi.nlm.nih.gov/20139894
https://pubmed.ncbi.nlm.nih.gov/20139894
Autor:
Hongyan Zhao, Wendy A. Boivin, Bruce M. McManus, David J. Granville, Rani P. Cruz, Jonathan C. Choy
Publikováno v:
The FASEB Journal. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::727e60935f936fa85c4abd892554ec39
https://doi.org/10.1096/fasebj.22.1_supplement.174.9
https://doi.org/10.1096/fasebj.22.1_supplement.174.9