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pro vyhledávání: '"Wendy A Camejo Nunez"'
Autor:
Emily E. Bramel, Tyler J. Creamer, Muzna Saqib, Wendy A. Camejo Nunez, Rustam Bagirzadeh, LaToya Ann Roker, Loyal A. Goff, Elena Gallo MacFarlane
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Heterozygous, loss of function mutations in positive regulators of the Transforming Growth Factor-β (TGF-β) pathway cause hereditary forms of thoracic aortic aneurysm. It is unclear whether and how the initial signaling deficiency triggers secondar
Externí odkaz:
https://doaj.org/article/4c3c141c39ab4539a19fe9950090de1a
Autor:
Emily E. Bramel, Tyler J. Creamer, Muzna Saqib, Wendy A. Camejo Nunez, Rustam Bagirzadeh, LaToya Ann Roker, Loyal A. Goff, Elena Gallo MacFarlane
Publikováno v:
Frontiers in cardiovascular medicine. 9
Heterozygous, loss of function mutations in positive regulators of the Transforming Growth Factor-β (TGF-β) pathway cause hereditary forms of thoracic aortic aneurysm. It is unclear whether and how the initial signaling deficiency triggers secondar
Autor:
Emily E Bramel, Tyler J Creamer, Muzna Saqib, Wendy A Camejo Nunez, Loyal A Goff, Elena Gallo MacFarlane
Publikováno v:
Circulation. 144
The pathogenesis of aortic aneurysms caused by mutations that impair TGF-β/Smad signaling without completely ablating it remains unclear. To investigate TGF-β’s role independently of its developmental functions, we used mouse models to inactivate