Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Wendy A Burgers"'
Autor:
Catherine Riou, Jinal N Bhiman, Yashica Ganga, Shobna Sawry, Frances Ayres, Richard Baguma, Sashkia R Balla, Ntombi Benede, Mallory Bernstein, Asiphe S Besethi, Sandile Cele, Carol Crowther, Mrinmayee Dhar, Sohair Geyer, Katherine Gill, Alba Grifoni, Tandile Hermanus, Haajira Kaldine, Roanne S Keeton, Prudence Kgagudi, Khadija Khan, Erica Lazarus, Jean Le Roux, Gila Lustig, Mashudu Madzivhandila, Siyabulela F J Magugu, Zanele Makhado, Nelia P Manamela, Qiniso Mkhize, Paballo Mosala, Thopisang P Motlou, Hygon Mutavhatsindi, Nonkululeko B Mzindle, Anusha Nana, Rofhiwa Nesamari, Amkele Ngomti, Anathi A Nkayi, Thandeka P Nkosi, Millicent A Omondi, Ravindre Panchia, Faeezah Patel, Alessandro Sette, Upasna Singh, Strauss van Graan, Elizabeth M Venter, Avril Walters, Thandeka Moyo-Gwete, Simone I Richardson, Nigel Garrett, Helen Rees, Linda-Gail Bekker, Glenda Gray, Wendy A Burgers, Alex Sigal, Penny L Moore, Lee Fairlie
Publikováno v:
PLOS Global Public Health, Vol 4, Iss 4, p e0002703 (2024)
We report the safety and immunogenicity of fractional and full dose Ad26.COV2.S and BNT162b2 in an open label phase 2 trial of participants previously vaccinated with a single dose of Ad26.COV2.S, with 91.4% showing evidence of previous SARS-CoV-2 in
Externí odkaz:
https://doaj.org/article/ffaf584224f64bc08915eb129bbe87ff
Autor:
Thandeka Moyo-Gwete, Simone I Richardson, Roanne Keeton, Tandile Hermanus, Holly Spencer, Nelia P Manamela, Frances Ayres, Zanele Makhado, Thopisang Motlou, Marius B Tincho, Ntombi Benede, Amkele Ngomti, Richard Baguma, Masego V Chauke, Mathilda Mennen, Marguerite Adriaanse, Sango Skelem, Ameena Goga, Nigel Garrett, Linda-Gail Bekker, Glenda Gray, Ntobeko A B Ntusi, Catherine Riou, Wendy A Burgers, Penny L Moore
Publikováno v:
PLoS Pathogens, Vol 19, Iss 11, p e1011772 (2023)
The impact of previous SARS-CoV-2 infection on the durability of Ad26.COV2.S vaccine-elicited responses, and the effect of homologous boosting has not been well explored. We followed a cohort of healthcare workers for 6 months after receiving the Ad2
Externí odkaz:
https://doaj.org/article/91047fe84ba14a82b86c46c0f2555468
Autor:
Sarika Jugwanth, Maemu P Gededzha, Nakampe Mampeule, Nontobeko Zwane, Anura David, Wendy A Burgers, Jonathan M Blackburn, Jurette S Grove, Jaya A George, Ian Sanne, Lesley Scott, Wendy Stevens, Elizabeth S Mayne
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0262442 (2022)
In late December 2019, pneumonia cases of unknown origin were reported in Wuhan, China. This virus was named SARS-CoV2 and the clinical syndrome was named coronavirus disease 19 (COVID-19). South Africa, despite strict and early lockdown has the high
Externí odkaz:
https://doaj.org/article/f79ba5eb04234494bda840cca4478e31
Autor:
Maemu P Gededzha, Nakampe Mampeule, Sarika Jugwanth, Nontobeko Zwane, Anura David, Wendy A Burgers, Jonathan M Blackburn, Jurette S Grove, Jaya A George, Ian Sanne, Lesley Scott, Wendy Stevens, Elizabeth S Mayne
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252317 (2021)
Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) has been identified as the causative agent for causing the clinical syndrome of COVID -19. Accurate detection of SARS-CoV-2 infection is not only important for management of infected indivi
Externí odkaz:
https://doaj.org/article/249627c590bb4141a098e3611eebba7f
Autor:
Lycias Zembe, Wendy A Burgers, Heather B Jaspan, Linda-Gail Bekker, Helba Bredell, Gwynneth Stevens, Jill Gilmour, Josephine H Cox, Patricia Fast, Peter Hayes, Eftyhia Vardas, Carolyn Williamson, Clive M Gray
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26096 (2011)
The genetic diversity of HIV-1 across the globe is a major challenge for developing an HIV vaccine. To facilitate immunogen design, it is important to characterize clusters of commonly targeted T-cell epitopes across different HIV clades. To address
Externí odkaz:
https://doaj.org/article/531e3acd2369445ba7f51746fce1fa88
Autor:
Ntombi S. B. Benede, Marius B. Tincho, Avril Walters, Vennesa Subbiah, Amkele Ngomti, Richard Baguma, Claire Butters, Mathilda Mennen, Sango Skelem, Marguerite Adriaanse, Strauss van Graan, Sashkia R. Balla, Thandeka Moyo-Gwete, Penny L. Moore, Maresa Botha, Lesley Workman, Heather J. Zar, Ntobeko A. B. Ntusi, Liesl Zühlke, Kate Webb, Catherine Riou, Wendy A. Burgers, Roanne S. Keeton
Publikováno v:
medRxiv
SUMMARYSARS-CoV-2 infection in children typically results in asymptomatic or mild disease. There is a paucity of studies on antiviral immunity in African children. We investigated SARS-CoV-2-specific T cell responses in 71 unvaccinated asymptomatic S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c775f7940cc6df55684a0b453a3ab4d
https://doi.org/10.1101/2023.05.16.23290059
https://doi.org/10.1101/2023.05.16.23290059
Autor:
Cosnet L. Rametse, Anthonio O. Adefuye, Abraham J. Olivier, Lyle Curry, Hoyam Gamieldien, Wendy A. Burgers, David A. Lewis, Anna-Lise Williamson, Arieh A. Katz, Jo-Ann S. Passmore
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Genital inflammatory cytokine responses increase HIV risk. Since male partner semen is a complex mixture of immune-modulatory prostaglandins and cytokines, we hypothesized that exposure to semen may influence genital inflammation in women. Here, we i
Externí odkaz:
https://doaj.org/article/91d39d2886b04281945d179ceefeaaa9
Autor:
Roanne Keeton, Marius B. Tincho, Amkele Ngomti, Richard Baguma, Ntombi Benede, Akiko Suzuki, Khadija Khan, Sandile Cele, Mallory Bernstein, Farina Karim, Sharon V. Madzorera, Thandeka Moyo-Gwete, Mathilda Mennen, Sango Skelem, Marguerite Adriaanse, Daniel Mutithu, Olukayode Aremu, Cari Stek, Elsa du Bruyn, Mieke A. Van Der Mescht, Zelda de Beer, Talita R. de Villiers, Annie Bodenstein, Gretha van den Berg, Adriano Mendes, Amy Strydom, Marietjie Venter, Jennifer Giandhari, Yeshnee Naidoo, Sureshnee Pillay, Houriiyah Tegally, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Robert J. Wilkinson, Tulio de Oliveira, Linda-Gail Bekker, Glenda Gray, Veronica Ueckermann, Theresa Rossouw, Michael T. Boswell, Jinal N. Bhiman, Penny L. Moore, Alex Sigal, Ntobeko A. B. Ntusi, Wendy A. Burgers, Catherine Riou
Publikováno v:
Nature
The SARS-CoV-2 Omicron variant (B.1.1.529) has multiple spike protein mutations1,2 that contribute to viral escape from antibody neutralization3–6 and reduce vaccine protection from infection7,8. The extent to which other components of the adaptive
Autor:
Roanne Keeton, Marius B. Tincho, Akiko Suzuki, Ntombi Benede, Amkele Ngomti, Richard Baguma, Masego V. Chauke, Mathilda Mennen, Sango Skelem, Marguerite Adriaanse, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Linda-Gail Bekker, Glenda Gray, Ntobeko A.B. Ntusi, Wendy A. Burgers, Catherine Riou
Publikováno v:
Cell reports. Medicine.
Multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposures, from infection or vaccination, can potently boost spike antibody responses. Less is known about the impact of repeated exposures on T cell responses. Here, we compare th
Autor:
Thandeka Moyo-Gwete, Mashudu Madzivhandila, Nonhlanhla N Mkhize, Prudence Kgagudi, Frances Ayres, Bronwen E Lambson, Nelia P Manamela, Simone I Richardson, Zanele Makhado, Mieke A van der Mescht, Zelda de Beer, Talita Roma de Villiers, Wendy A Burgers, Ntobeko A B Ntusi, Theresa Rossouw, Veronica Ueckermann, Michael T Boswell, Penny L Moore
Publikováno v:
Journal of Virology. 96
As SARS-CoV-2 continues to evolve, several variants of concern (VOCs) have arisen which are defined by multiple mutations in their spike proteins. These VOCs have shown variable escape from antibody responses, and have been shown to trigger qualitati