Výsledky vyhledávání - "Wendra M. Foster"

Coding variants in PNPLA3 and TM6SF2 are risk factors for hepatic steatosis and elevated serum alanine aminotransferases caused by a glucagon receptor antagonist

Autor: Naga Chalasani, Thomas Hardy, Suman Duvvuru, Sudha S. Shankar, Anthony Akkari, Xiaotian Michelle Zhang, Sreekumar G. Pillai, Christof M. Kazda, Mark A. Deeg, Chakib Battioui, Pallav Bhatnagar, Wendra M. Foster, Cristina B. Guzman

Publikováno v: Hepatology Communications. 2:561-570

LY2409021 is a glucagon receptor antagonist that was associated with hepatic steatosis and elevated aminotransferases in phase 2 diabetes studies. We investigated the relationship between selected genetic variants and hepatic steatosis and elevated a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::29415cd08f7a70309a76379dfe48093e
https://doi.org/10.1002/hep4.1171

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The PNPLA3 I148M variant is associated with transaminase elevations in type 2 diabetes patients treated with basal insulin peglispro

Autor: Edward J. Bastyr, Wendra M. Foster, Sreekumar G. Pillai, Axel Haupt, M Farmen, Byron J. Hoogwerf, C Harris, Suman Duvvuru, Sudha S. Shankar, Pallav Bhatnagar

Publikováno v: The pharmacogenomics journal. 18(3)

Basal insulin peglispro (BIL) is a novel insulin with hepato-preferential action. In phase 3 trials, BIL showed significantly improved glycemic control but higher levels of transaminases (alanine aminotransferase (ALT) and aspartate aminotransferase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da17d6039ad365fd757b48b9785b21cf
https://pubmed.ncbi.nlm.nih.gov/29160303

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ADCY9 Genetic Variants and Cardiovascular Outcomes With Evacetrapib in Patients With High-Risk Vascular Disease

Autor: Pallav Bhatnagar, Jeffrey S. Riesmeyer, Ellen McErlean, Kathy Wolski, Sreekumar G. Pillai, Stephen J. Nicholls, Giacomo Ruotolo, Wendra M. Foster, Govinda Weerakkody, A. Michael Lincoff, Steven E. Nissen, Lin Li

Publikováno v: JAMA Cardiology. 3:401

Steven E. Nissen, Sreekumar G. Pillai, Stephen J. Nicholls, KathyWolski, Jeffrey S. Riesmeyer, Govinda J.Weerakkody, WendraM. Foster, Ellen McErlean, Lin Li, Pallav Bhatnagar, Giacomo Ruotolo, A. Michael Lincoff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b40e0b47ccc2ea7588e80cd68b53afb
https://doi.org/10.1001/jamacardio.2018.0569

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Candidate Gene Associations with Vaso-Occlusive Crisis in Children with Sickle Cell Anemia Enrolled in the Multinational DOVE Trial

Autor: Lori E. Heath, Carolyn Hoppe, Bhatnagar Pallav, Wendra M. Foster, Joseph A. Jakubowski, Sreekumar G. Pillai

Publikováno v: Blood. 130:962-962

Introduction: Sickle cell disease (SCD) is complex, with marked inter-individual variability in disease severity. The clinical heterogeneity of SCD is largely influenced by genetic factors, including several well-established modifiers of fetal hemogl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d691c990d73205038fd64694c6af201
https://doi.org/10.1182/blood.v130.suppl_1.962.962

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