Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Wendou Yu"'
Autor:
Derek M. Dykxhoorn, Adam R. Williams, Michael A. Bellio, Joshua M. Hare, Konstantinos E. Hatzistergos, Wendou Yu
Publikováno v:
Circulation Research. 124:1184-1197
Rationale: Although rare cardiomyogenesis is reported in the adult mammalian heart, whether this results from differentiation or proliferation of cardiomyogenic cells remains controversial. The tumor suppressor genes RB1 (retinoblastoma) and CDKN2a (
Autor:
Song Liu, Tomoyo Sawada, Seongsoo Lee, Wendou Yu, George Silverio, Philomena Alapatt, Ivan Millan, Alice Shen, William Saxton, Tomoko Kanao, Ryosuke Takahashi, Nobutaka Hattori, Yuzuru Imai, Bingwei Lu
Publikováno v:
PLoS Genetics, Vol 8, Iss 3, p e1002537 (2012)
Mutations in Pten-induced kinase 1 (PINK1) are linked to early-onset familial Parkinson's disease (FPD). PINK1 has previously been implicated in mitochondrial fission/fusion dynamics, quality control, and electron transport chain function. However, i
Externí odkaz:
https://doaj.org/article/4ddc5e023a0a462b8d1a24398e510dd1
Autor:
Wendou Yu, Bingwei Lu
Publikováno v:
Neural Plasticity, Vol 2012 (2012)
Synapses are sites of cell-cell contacts that transmit electrical or chemical signals in the brain. Dendritic spines are protrusions on dendritic shaft where excitatory synapses are located. Synapses and dendritic spines are dynamic structures whose
Externí odkaz:
https://doaj.org/article/33faafecac4a4e46ae2cf382c05fcd45
Autor:
Konstantinos E, Hatzistergos, Adam R, Williams, Derek, Dykxhoorn, Michael A, Bellio, Wendou, Yu, Joshua M, Hare
Publikováno v:
Circulation research. 124(8)
Although rare cardiomyogenesis is reported in the adult mammalian heart, whether this results from differentiation or proliferation of cardiomyogenic cells remains controversial. The tumor suppressor genes RB1 (retinoblastoma) and CDKN2a (cyclin-depe
Autor:
Evan G. Cameron, Michael Nahmou, Xin Xia, Tomasz Boczek, Jeffrey L. Goldberg, Michael S. Kapiloff, Wendou Yu, Sahil Shah, Joana Galvao, Jinliang Li, Boris Castillo Chabeco, Hrishikesh Thakur
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 39(28)
cAMP signaling is known to be critical in neuronal survival and axon growth. Increasingly the subcellular compartmentation of cAMP signaling has been appreciated, but outside of dendritic synaptic regulation, few cAMP compartments have been defined i
Autor:
Boczek, Tomasz, Cameron, Evan G., Wendou Yu, Xin Xia, Shah, Sahil H., Chabeco, Boris Castillo, Galvao, Joana, Nahmou, Michael, Jinliang Li, Thakur, Hrishikesh, Goldberg, Jeffrey L., Kapiloff, Michael S.
Publikováno v:
Journal of Neuroscience; 7/10/2019, Vol. 39 Issue 28, p5466-5480, 15p
Autor:
James E. Cox, Un Na, Carl S. Thummel, Dennis R. Winge, Daniel K. Bricker, Wendou Yu, Jared Rutter, Knut Brockmann
Publikováno v:
Cell Metabolism. 20:253-266
SummaryDisorders arising from impaired assembly of succinate dehydrogenase (SDH) result in a myriad of pathologies, consistent with its unique role in linking the citric acid cycle and electron transport chain. In spite of this critical function, how
Autor:
Jayakumar Rajadas, Robert C. Malenka, Bingwei Lu, Wendou Yu, Jai S. Polepalli, Dhananjay Wagh
Publikováno v:
Human Molecular Genetics. 21:1384-1390
Alzheimer's disease (AD) is the most common neurodegenerative disease and the leading cause of dementia in the elderly. Accumulating evidence supports soluble amyloid-β (Aβ) oligomers as the leading candidate for the causative agent in AD and synap
Publikováno v:
Human Molecular Genetics. 20:3227-3240
PTEN-induced putative kinase 1 (PINK1) and Parkin act in a common pathway to regulate mitochondrial dynamics, the involvement of which in the pathogenesis of Parkinson's disease (PD) is increasingly being appreciated. However, how the PINK1/Parkin pa
Autor:
Rashid Ali, Rong Wen Li, Erik I. Charych, David R. Serwanski, Ben A. Bahr, Wendou Yu, Angel L. De Blas
Publikováno v:
Journal of Neurochemistry. 105:2300-2314
We have previously shown that the glutamate receptor interacting protein 1 (GRIP1) splice forms GRIP1a/b and GRIP1c4–7 are present at the GABAergic post-synaptic complex. Nevertheless, the role that these GRIP1 protein isoforms play at the GABAergi