Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Wendol Williams"'
Autor:
Rajiv Radhakrishnan, Nabeel Nabulsi, Edward Gaiser, Jean-Dominique Gallezot, Shannan Henry, Beata Planeta, Shu-fei Lin, Jim Ropchan, Wendol Williams, Evan Morris, Deepak Cyril D’Souza, Yiyun Huang, Richard E. Carson, David Matuskey
Publikováno v:
Journal of Clinical and Translational Science, Vol 2, Pp 3-4 (2018)
OBJECTIVES/SPECIFIC AIMS: The serotonin receptor 6 (5-HT6) is a potential therapeutic target given its distribution in brain regions that are important in depression, anxiety, and cognition. This study sought to investigate the effects of age on 5-HT
Externí odkaz:
https://doaj.org/article/9b7f331f23664c908f1e521eae84abf8
Autor:
Jean-Dominique Gallezot, Shannan Henry, David Matuskey, Shu-fei Lin, Jim Ropchan, Nabeel Nabulsi, Deepak Cyril D'Souza, Evan D. Morris, Edward C. Gaiser, Wendol Williams, Beata Planeta, Rajiv Radhakrishnan, Richard E. Carson, Yiyun Huang
Serotonin receptor 6 (5-hydroxytrypamine-6, or 5-HT(6)) is a potential therapeutic target given its distribution in brain regions that are important in depression, anxiety, and cognition. This study sought to investigate the effects of age on 5-HT(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::748ceebc20a3f117356ec66ee4bb17e0
https://europepmc.org/articles/PMC6126437/
https://europepmc.org/articles/PMC6126437/
Autor:
Beata Planeta, Wendol Williams, Richard E. Carson, Jean-Dominique Gallezot, Jenna M. Sullivan, Jim Ropchan, Yu-Shin Ding, Timothy J. McCarthy, Shu-fei Lin, Evan D. Morris, Yiyun Huang, Eunkyung Park, Keunpoong Lim
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 42:1530-1541
[(18)F]FPEB is a promising PET radioligand for the metabotropic glutamate receptor 5 (mGluR5), a potential target for the treatment of neuropsychiatric diseases. The purpose of this study was to evaluate the test-retest reproducibility of [(18)F]FPEB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10c1eec327938958198f0bd54d0b57ed
https://doi.org/10.1007/s00259-015-3094-6
https://doi.org/10.1007/s00259-015-3094-6
Autor:
Wendol Williams, Marc N. Potenza, David Labaree, Shu-fei Lin, David Matuskey, Robert T. Malison, Jonas Hannestad, Jean-Dominique Gallezot, Jane Wanyiri, Edward C. Gaiser, Richard E. Carson, Keunpoong Lim, Dianne Lee, Yu-Shin Ding, Brian Pittman, Minq-Qiang Zheng
Publikováno v:
Drug and Alcohol Dependence. 139:100-105
Background Evidence from animal models and postmortem human studies points to the importance of the dopamine D3 receptor (D3R) in cocaine dependence (CD). The objective of this pilot study was to use the D3R-preferring radioligand [11C](+)PHNO to com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da3a6be62280ca00936bbee3cd2810d2
https://doi.org/10.1016/j.drugalcdep.2014.03.013
https://doi.org/10.1016/j.drugalcdep.2014.03.013
Autor:
Edward C. Gaiser, Shu-fei Lin, Deepak Cyril D'Souza, Nabeel Nabulsi, David Matuskey, Evan D. Morris, Beata Planeta, Rajiv Radhakrishnan, Jim Ropchan, Richard Carson, Wendol Williams, Shannan Henry, Jean-Dominique Gallezot, Yiyun Huang
Publikováno v:
Journal of Clinical and Translational Science
OBJECTIVES/SPECIFIC AIMS: The serotonin receptor 6 (5-HT6) is a potential therapeutic target given its distribution in brain regions that are important in depression, anxiety, and cognition. This study sought to investigate the effects of age on 5-HT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d01700cb899dad0c0a6d2f09fdd9c59
https://doi.org/10.1017/cts.2018.44
https://doi.org/10.1017/cts.2018.44
Autor:
Soheila Najafzadeh, Wendol Williams, Beata Planeta, Shu-fei Lin, Nabeel Nabulsi, Yiyun Huang, Jean-Dominique Gallezot, David Labaree, Mika Naganawa, Alexander Neumeister, Jim Ropchan, Richard E. Carson
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 33:1886-1896
[11C]AFM, or [11C]2-[2-(dimethylaminomethyl)phenylthio]-5-fluoromethylphenylamine, is a new positron emission tomography (PET) radioligand with high affinity and selectivity for the serotonin transporter (SERT). The purpose of this study was to deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32eeed115882ca7f1e1ec93292074c5
https://doi.org/10.1038/jcbfm.2013.134
https://doi.org/10.1038/jcbfm.2013.134
Autor:
Wendol Williams, Yiyun Huang, James W. Murrough, Shannan Henry, Jian Hu, Alexander Neumeister, John H. Krystal, Richard E. Carson, Jean-Dominique Gallezot, Christopher R. Bailey
Publikováno v:
Biological Psychiatry. 70:1033-1038
Background The amygdala is a key site where alterations in the regulation of the serotonin transporter (5-HTT) may alter stress response. Deficient 5-HTT function and abnormal amygdala activity have been hypothesized to contribute to the pathophysiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d8d9415246e4cda59d7570916e4290c
https://doi.org/10.1016/j.biopsych.2011.07.003
https://doi.org/10.1016/j.biopsych.2011.07.003
Autor:
Jean-Dominique Gallezot, Wendol Williams, Robert T. Malison, Beata Planeta-Wilson, Christopher H. van Dyck, Jonas Hannestad, Yu-Shin Ding, Shu-fei Lin, Richard E. Carson
Publikováno v:
Biological Psychiatry. 68:854-860
Background Attention-deficit/hyperactivity disorder is a psychiatric disorder that starts in childhood. The mechanism of action of methylphenidate, the most common treatment for attention deficit hyperactivity disorder, is unclear. In vitro, the affi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dad658326bc5f083d2e01b21f74004a7
https://doi.org/10.1016/j.biopsych.2010.06.017
https://doi.org/10.1016/j.biopsych.2010.06.017
Autor:
David Labaree, Tarun Singhal, Beata Planeta-Wilson, Jean-Dominique Gallezot, Alexander Neumeister, Nabeel Nabulsi, Robert T. Malison, Wendol Williams, Shannan Henry, Jim Ropchan, Yu-Shin Ding, Richard E. Carson
Publikováno v:
Synapse. 64:30-38
The role of the norepinephrine transporter (NET) in cocaine dependence has never been demonstrated via in vivo imaging due to the lack of suitable NET radioligands. Here we report our preliminary studies evaluting the NET in individuals with cocaine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfad456d8820509d7a3188f8475cfc6d
https://doi.org/10.1002/syn.20696
https://doi.org/10.1002/syn.20696
Autor:
Alexander Neumeister, Sunhee Kim, Wendol Williams, Yiyun Huang, Timothy J. McCarthy, J. James Frost, R. Paul Maguire, Richard E. Carson, Nabeel Nabulsi, Tarun Singhal, Beata Planeta-Wilson, Yu-Shin Ding, Jean-Dominique Gallezot
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 30:196-210
[11C]P943 is a new radioligand recently developed to image and quantify serotonin 5-Hydroxytryptamine (5-HT1B) receptors with positron emission tomography (PET). The purpose of this study was to evaluate [11C]P943 for this application in humans, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9fb0a415d4b24c5ae11ce3918ee972
https://doi.org/10.1038/jcbfm.2009.195
https://doi.org/10.1038/jcbfm.2009.195