Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Wendie S. Cohick"'
Publikováno v:
Toxins, Vol 3, Iss 5, Pp 453-468 (2011)
Ricin is a highly toxic type II ribosome-inactivating protein that has potential as a biochemical weapon and as the toxic component of immunotoxins. The unfolded protein response (UPR) is a survival response that helps cells to recover from endoplasm
Externí odkaz:
https://doaj.org/article/cbe466e00a2946578775a4e16004d0b1
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162662 (2016)
A role for estrogens in breast cancer is widely accepted, however, recent evidence highlights that timing and exposure levels are important in determining whether they elicit harmful versus beneficial effects. The rat chemical carcinogen model has be
Externí odkaz:
https://doaj.org/article/b4c7b193a88b456aa4595dd8661df217
Publikováno v:
Alcohol Clin Exp Res
Background Fetal alcohol exposure (FAE) increases the risk of mammary tumorigenesis in adult offspring; however, the underlying mechanism remains unknown. This study tested the hypothesis that FAE shifts the mammary epithelial cell (MEC) composition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d9160a275bf068996a24f0d11dd143
https://doi.org/10.1111/acer.14308
https://doi.org/10.1111/acer.14308
Autor:
Allyson Agostini-Dreyer, Amanda E. Jetzt, Wendie S. Cohick, Jennifer Hanke, Jennifer A. Skorupa
Publikováno v:
Journal of the Endocrine Society
IGF-binding protein (IGFBP)-3 is a multifunctional protein that can exert IGF-independent effects on apoptosis. Anisomycin (ANS) is a potent inducer of IGFBP-3 production in bovine mammary epithelial cells (MECs), and knockdown of IGFBP-3 attenuates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bdba0cfd27621f5e42597d1584ac6f8
http://europepmc.org/articles/PMC6371081
http://europepmc.org/articles/PMC6371081
Publikováno v:
Integrative Organismal Biology
Synopsis Previous research has demonstrated that testosterone (T) can inhibit growth in female-larger species and stimulate growth in male-larger species, but the underlying mechanisms of this regulatory bipotentiality have not been investigated. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb1e952485a08306991ec8491f4c8f2
http://europepmc.org/articles/PMC7715992
http://europepmc.org/articles/PMC7715992
Publikováno v:
Poultry Science. 97:2203-2206
Sturkie's Avian Physiology is a highly regarded textbook for the study of comparative poultry physiology. Less well known, however, is the contribution of Paul D. Sturkie (1909-2002) as a pioneer in the experimental physiology of avian species. His s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1131ed8926f356e9138d1af29941ea27
https://doi.org/10.3382/ps/pey072
https://doi.org/10.3382/ps/pey072
Publikováno v:
Alcoholism: Clinical and Experimental Research. 40:1679-1690
Background Alcohol exposure in utero increases susceptibility to carcinogen-induced mammary tumorigenesis in adult offspring and causes tumors with a more malignant phenotype. This study was conducted to identify changes early in tumor development th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69718227512a93cd08f8abc27a638e5b
https://doi.org/10.1111/acer.13139
https://doi.org/10.1111/acer.13139
Autor:
Wendie S. Cohick
Publikováno v:
Journal of Animal Science. 94:1812-1820
Differentiation of the mammary gland during pregnancy and the first several days following parturition is required for the establishment of a normal lactation. The expansion and development of the secretory compartment into lobuloalveloar structures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0670466149de92cf72a6f4b12449c9fe
https://doi.org/10.2527/jas.2015-0085
https://doi.org/10.2527/jas.2015-0085
Publikováno v:
Endocrinology. 156:4141-4151
In nontransformed bovine mammary epithelial cells, the intrinsic apoptosis inducer anisomycin (ANS) induces IGFBP-3 expression and nuclear localization and knockdown of IGFBP-3 attenuates ANS-induced apoptosis. Others have shown in prostate cancer ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ff84643243bae44b663b4f7fd124c1
https://doi.org/10.1210/en.2015-1215
https://doi.org/10.1210/en.2015-1215
Ricin is a potent ribotoxin that is considered a bioterror threat due to its ease of isolation and possibility of aerosolization. In yeast, mutation of arginine residues away from the active site results in a ricin toxin A chain (RTA) variant that is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f414a6e55fe1e18031825cc963cd355
https://europepmc.org/articles/PMC5079286/
https://europepmc.org/articles/PMC5079286/
