Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Wendi S, Lambert"'
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65389 (2013)
Oxidative stress has been implicated in neurodegenerative diseases, including glaucoma. However, due to the lack of clinically relevant models and expense of long-term testing, few studies have modeled antioxidant therapy for prevention of neurodegen
Externí odkaz:
https://doaj.org/article/b3ce1f86f9374f8bbc4212eb11cc66fe
Autor:
David J. Calkins, Silvia Pasini, John W. Collyer, Wendi S. Lambert, Brian J. Carlson, Cathryn R. Formichella, Purnima Ghose
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-20 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-20 (2020)
Glaucoma is a group of optic neuropathies associated with aging and sensitivity to intraocular pressure (IOP). Early progression involves retinal ganglion cell (RGC) axon dysfunction that precedes frank degeneration. Previously we demonstrated that p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b62f06b97360d7c9814c9786198124e
http://europepmc.org/articles/PMC7244559
http://europepmc.org/articles/PMC7244559
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Identifying new therapies for neurodegenerative disease requires understanding how neurons respond to stress and whether this response includes adaptation to slow progression. Because neurodegeneration affects both axons and dendrites, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf6b35a0a835f0880dee4015328b742
http://europepmc.org/articles/PMC5877940
http://europepmc.org/articles/PMC5877940
Autor:
Purnima Ghose, Victoria Vest, Vincent Yao, Brian J. Carlson, Wendi S. Lambert, David J. Calkins
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Glaucoma is a group of optic neuropathies associated with aging and sensitivity to intraocular pressure (IOP). The disease causes vision loss through the degeneration of retinal ganglion cell neurons and their axons in the optic nerve. Using an induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6974482c15ab6996301e8d09594ad834
https://pubmed.ncbi.nlm.nih.gov/31399621
https://pubmed.ncbi.nlm.nih.gov/31399621
Publikováno v:
Exp Eye Res
Glaucoma is an age-related neurodegenerative disease that is commonly associated with sensitivity to intraocular pressure. The disease selectively targets retinal ganglion cells (RGCs) and constituent axons. RGC axons are rich in voltage-gated sodium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2345c9bb48dcd462db172f84174b454d
https://doi.org/10.1016/j.exer.2019.107873
https://doi.org/10.1016/j.exer.2019.107873
Autor:
David J, Calkins, Wendi S, Lambert, Cathryn R, Formichella, William M, McLaughlin, Rebecca M, Sappington
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1695
Glaucoma is a common optic neuropathy that leads to vision loss through the degeneration of retinal ganglion cells (RGCs) and their axons. RGC degeneration in glaucoma is associated with sensitivity to intraocular pressure (IOP) and elevated IOP (als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2bd41c0028f190e8cb3b912793e1e46f
https://pubmed.ncbi.nlm.nih.gov/29190015
https://pubmed.ncbi.nlm.nih.gov/29190015
Autor:
David J. Calkins, Rebecca M. Sappington, Wendi S. Lambert, William M. McLaughlin, Cathryn R. Formichella
Publikováno v:
Glaucoma ISBN: 9781493974061
Glaucoma is a common optic neuropathy that leads to vision loss through the degeneration of retinal ganglion cells (RGCs) and their axons. RGC degeneration in glaucoma is associated with sensitivity to intraocular pressure (IOP) and elevated IOP (als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25d383de0d482713505f1022044f95d2
https://doi.org/10.1007/978-1-4939-7407-8_3
https://doi.org/10.1007/978-1-4939-7407-8_3
Autor:
Wendi S. Lambert, Richard M. Caprioli, Kevin L. Schey, David J. Calkins, David M. Anderson, Rosalie K. Crouch, Zsolt Ablonczy
Publikováno v:
Methods in Molecular Biology ISBN: 9781493970506
The visual system is comprised of many specialized cell types that are essential for relaying sensory information about an animal's surroundings to the brain. The cells present in ocular tissue are notoriously delicate, making it particularly challen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e3ffc85e6cd6d8a0e74fd49b6e8a1b0
https://doi.org/10.1007/978-1-4939-7051-3_3
https://doi.org/10.1007/978-1-4939-7051-3_3
Autor:
Rebecca M. Sappington, Tatiana N. Sidorova, David J. Calkins, Nicholas J. Ward, Wendi S. Lambert, Karen W. Ho, Carl Weitlauf
Publikováno v:
The Journal of Neuroscience. 34:15369-15381
Progression of neurodegeneration in disease and injury is influenced by the response of individual neurons to stressful stimuli and whether this response includes mechanisms to counter declining function. Transient receptor potential (TRP) cation cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::146573d8fdb0c1bc15ada87f935ea896
https://doi.org/10.1523/jneurosci.3424-14.2014
https://doi.org/10.1523/jneurosci.3424-14.2014
Publikováno v:
Glia. 62:1435-1451
Astrocytes provide metabolic, structural, and synaptic support to neurons in normal physiology and also contribute widely to pathogenic processes in response to stress or injury. Reactive astrocytes can undergo cytoskeletal reorganization and increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbf425b39c6ddadf7d9223e809374fbf
https://doi.org/10.1002/glia.22691
https://doi.org/10.1002/glia.22691