Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Wendell P, Griffith"'
Publikováno v:
Nutrients, Vol 16, Iss 3, p 348 (2024)
23-Hydroxy ursolic acid (23-OH UA) is a potent atheroprotective and anti-obesogenic phytochemical, with anti-inflammatory and inflammation-resolving properties. In this study, we examined whether dietary 23-OH UA protects mice against the acute onset
Externí odkaz:
https://doaj.org/article/a75482a3249d4ae9ad9d3a1862eb47c4
Profiling the repertoire of proteins associated with a given mRNA during the cell cycle is unstudied. Furthermore, it is much easier to ask and answer what mRNAs a specific protein might bind to than the other way around. Here, we implemented an RNA-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c66cd215309c251b35a3877259f0231
https://doi.org/10.1101/2023.05.02.539120
https://doi.org/10.1101/2023.05.02.539120
Publikováno v:
ACS Catalysis. 11:9869-9874
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::973a5472df9c99cd94409148a78f9521
https://doi.org/10.1021/acscatal.1c02674
https://doi.org/10.1021/acscatal.1c02674
Autor:
Michael P. Doyle, Wendell P. Griffith, Ahmad Humeidi, Xinfang Xu, Kuiyong Dong, Hadi D. Arman
Publikováno v:
Angewandte Chemie. 133:13506-13512
An unprecedented Ag(I)-catalyzed efficient method for the coupling of β-oxoimides and enol diazoacetates through a [3+2]-cycloaddition/C-O bond cleavage/[1,5]-proton transfer cascade process is reported. The general class of imino ethers that includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f19088c9eca9ad69653f2b3a66cbe52
https://doi.org/10.1002/ange.202101641
https://doi.org/10.1002/ange.202101641
Autor:
Wendell P. Griffith, Hadi D. Arman, Daniel J. Wherritt, Yong-Liang Su, Linh Tram, Michael P. Doyle
Publikováno v:
ACS Catalysis. 10:13682-13687
A general catalytic methodology for 1,2-RF/Y-difunctionalization of conjugated alkenes is reported. Diverse functionalized carbon radicals (RF•), which are generated through copper(I)-initiated sel...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d2caead6af92e8e347d34746673d9a9
https://doi.org/10.1021/acscatal.0c04243
https://doi.org/10.1021/acscatal.0c04243
Autor:
Ru He, Jhonti Chakraborty, Tanjila Islam, Hadi D. Arman, Wendell P. Griffith, Adam S. Veige, Kirk S. Schanze
Publikováno v:
Journal of Organometallic Chemistry. 976:122440
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fb49741ec3660d7e8f103cbe17ad576
https://doi.org/10.1016/j.jorganchem.2022.122440
https://doi.org/10.1016/j.jorganchem.2022.122440
Publikováno v:
J Am Chem Soc
Galactose oxidase (GAO) contains a Cu(II)-ligand radical cofactor. The cofactor, which is autocatalytically generated through the oxidation of the copper, consists of a cysteine-tyrosine radical (Cys-Tyr(•)) as a copper ligand. The formation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fba1120ef9081f8ce63d80de6cd0529b
https://pubmed.ncbi.nlm.nih.gov/33091303
https://pubmed.ncbi.nlm.nih.gov/33091303
Publikováno v:
J Biol Chem
Cysteamine dioxygenase (ADO) has been reported to exhibit two distinct biological functions with a nonheme iron center. It catalyzes oxidation of both cysteamine in sulfur metabolism and N-terminal cysteine-containing proteins or peptides, such as re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cd7d74dd38885e457bd772ac7793441
https://pubmed.ncbi.nlm.nih.gov/32601061
https://pubmed.ncbi.nlm.nih.gov/32601061
Autor:
Fahui Li, Aimin Liu, Yifan Wang, Inchul Shin, Daniel J. Wherritt, Ian Davis, Jiasong Li, Wendell P. Griffith, Jiangyun Wang
Publikováno v:
Nature chemical biology
Cysteine dioxygenase (CDO) plays an essential role in sulfur metabolism by regulating homeostatic levels of cysteine. Human CDO contains a post-translationally generated Cys93-Tyr157 cross-linked cofactor. Here, we investigated this Cys-Tyr cross-lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1a46b021afb66ecccf6659e8795b10
https://doi.org/10.1038/s41589-018-0085-5
https://doi.org/10.1038/s41589-018-0085-5
Autor:
Elizabeth Fritz, Teruaki Koto, Aimin Liu, Yifan Wang, Daniel J. Wherritt, Jiasong Li, Wendell P. Griffith
Publikováno v:
Angewandte Chemie. 130:8281-8285
Cysteamine dioxygenase (ADO) is a thiol dioxygenase whose study has been stagnated by the ambiguity as to whether or not it possesses an anticipated protein-derived cofactor. Reported herein is the discovery and elucidation of a Cys-Tyr cofactor in h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0af127c57e53ca55aeccb1de39dd52
https://doi.org/10.1002/ange.201803907
https://doi.org/10.1002/ange.201803907