Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Wendell D Jones"'
Autor:
Huixiao Hong, Lei Xu, Jie Liu, Wendell D Jones, Zhenqiang Su, Baitang Ning, Roger Perkins, Weigong Ge, Kelci Miclaus, Li Zhang, Kyunghee Park, Bridgett Green, Tao Han, Hong Fang, Christophe G Lambert, Silvia C Vega, Simon M Lin, Nadereh Jafari, Wendy Czika, Russell D Wolfinger, Federico Goodsaid, Weida Tong, Leming Shi
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44483 (2012)
During the last several years, high-density genotyping SNP arrays have facilitated genome-wide association studies (GWAS) that successfully identified common genetic variants associated with a variety of phenotypes. However, each of the identified ge
Externí odkaz:
https://doaj.org/article/f7b0abb5339e435fa63dd591f9847118
Autor:
Maryellen de Mars, Cu Nguyen, Tiffany Hung, Eric Peters, Charles Lu, Meijian Guan, Bao Tran, Maurizio Polano, Bin Zhu, Samir Lababidi, Wendell D. Jones, Chunlin Xiao, Andreas Scherer, K J. Langenbach, Zhipan Li, Luyao Ren, Weida Tong, Erich Jaeger, Rebecca Kusko, Zivana Tezak, Ying Yu, Ulrika Liljedahl, Louis M. Staudt, Huixiao Hong, Jing Wang, Yuanting Zheng, Ali Moshrefi, Cristobal Juan Vera, Chris Miller, Rasika Kalamegham, Arati Raziuddin, Howard Jacob, Roberta Maestro, Bindu Swapna Madala, Petr Vojta, Jessica Nordlund, Li Tai Fang, Jiri Drabek, Xuelu Liu, Corey Miles, Gary P. Schroth, Fayaz Seifuddin, Tim R. Mercer, Chunhua Yan, Leihong Wu, Sulev Kõks, Roderick V. Jensen, Jennifer A Hipp, Yun-Ching Chen, Malcolm Moos, Yongmei Zhao, Baitang Ning, Aparna Natarajan, Brian N. Papas, Xin Chen, Ashley Walton, Stephen T. Sherry, Christopher E. Mason, Liz Kerrigan, Ogan D Abaan, Wanqiu Chen, Kenneth Idler, Jingya Wang, Tsai-wei Shen, James C. Willey, Ene Reimann, Justin B. Lack, Virginie Petitjean, Jyoti Shetty, Daoud Meerzaman, Charles Wang, Jian-Liang Li, Tiffany Truong, Keyur Talsania, Mehdi Pirooznia, Marc Sultan, Urvashi Mehra, Wenming Xiao, Zhong Chen, Ana Granat, Leming Shi, Margaret C. Cam, Qing-Rong Chen, Eric F. Donaldson, Wolfgang Resch, Ben Ernest, Yuliya Kriga, Gokhan Yavas, Thomas M. Blomquist, Parthav Jailwala
Publikováno v:
Nat Biotechnol
Clinical applications of precision oncology require accurate tests that can distinguish true cancer-specific mutations from errors introduced at each step of next-generation sequencing (NGS). To date, no bulk sequencing study has addressed the effect
Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
Autor:
Agda Karina Eterovic, Rebecca Ringler, Binsheng Gong, Jiashi Wang, Christopher E. Mason, Garima Kushwaha, Abhisek Ghosal, James C. Willey, Zhihong Zhang, Wenzhong Xiao, Natalia Novoradovskaya, Joshua Xu, Mary Yang, Zhiguang Li, Leihong Wu, Philippe Szankasi, Paul Rindler, Suman Verma, Simon Cawley, Daniel Stetson, Yilin Zhang, Fergal Casey, Nathan Haseley, Fujun Qiu, Paula Proszek, Mirna Jarosz, Ira W. Deveson, Kevin Lai, Donald J. Johann, Rebecca Kusko, Haowen Tan, Tim R. Mercer, Chia Jung Chang, Kristina Giorda, Tieliu Shi, Blake Burgher, Kyle Horvath, Leming Shi, Pierre R. Bushel, Guangchun Chen, Melissa Smith, Igor Stevanovski, Devin W. Close, Liang Feng, Lin-ya Tang, Liang-Chun Liu, Todd Richmond, Wendell D. Jones, Daniel Duncan, Andreas Scherer, Jorge Dinis, Chang Xu, Rita Shaknovich, Tom Morrison, Ping Song, Nikola Tom, Weida Tong, Quan Zhen Li, Lihyun Sun, Charles Ma, Dalila B. Megherbi, Robert Sebra, Sean Glenn, Narasimha Marella, Ambica Bhandari, Jennifer S. LoCoco, Zhichao Liu, Jeoffrey Schageman, Mehdi Pirooznia, Scott Happe, Hanane Arib, Maya Strahl, Dan Li, Hunter Best, Venkat J. Thodima, Amelia Raymond, Jeffrey Conroy, Mike Hubank, Piotr A. Mieczkowski, Carlos Pabón-Peña, James Blackburn, Li-Yuan Hung, Sa Zhang, Bindu Swapna Madala, Guangliang Zhang, Jonathan Choi
Publikováno v:
Nature biotechnology
Circulating tumor DNA (ctDNA) sequencing is being rapidly adopted in precision oncology, but the accuracy, sensitivity, and reproducibility of ctDNA assays is poorly understood. Here we report the findings of a multi-site, cross-platform evaluation o
Autor:
Ram N. Ganapathi, Nury Steuerwald, Kaitlin E. Klotz, Eric J. Norris, Wendell D. Jones, Mahrukh K. Ganapathi, Jaroslaw P. Maciejewski, Yogin Patel
Publikováno v:
Leukemia & Lymphoma. 62:473-477
All trans retinoic acid (ATRA) has demonstrated curative activity in acute promyelocytic leukemia (APL), a distinct subtype of acute myeloid leukemia (AML), that is characterized by a chromosomal t...
Autor:
Thomas Holcomb, F. Anthony Romero, Jeffrey Eastham-Anderson, Shrividhya Srinivasan, Vicki Plaks, Mark R. Lackner, Somayeh S. Tarighat, Esther Wu, Katherine E. Hutchinson, Matthew P. Stokes, Andrew Glibicky, Ron McCord, Wendell D. Jones, Melissa Gonzalez Edick, Bonnie Liu, Sangeeta K. Jayakar, Marie-Claire Wagle, Joseph Castillo, Jennifer M. Giltnane, Christopher Lowe, Steven Magnuson, Zineb Mounir, Shih-Min A. Huang
Publikováno v:
Cancer Research. 79:3916-3927
Regulatory T cells (Treg) are immunosuppressive and negatively impact response to cancer immunotherapies. CREB-binding protein (CBP) and p300 are closely related acetyltransferases and transcriptional coactivators. Here, we evaluate the mechanisms by
Autor:
David L. Tait, Wendell D. Jones, Chad A. Livasy, Eric J. Norris, Mahrukh K. Ganapathi, Darla Destephanis, Ram N. Ganapathi, Qing Zhang, Ashley P. Sutker
Publikováno v:
The Journal of Pathology
High grade serous ovarian carcinoma (HGSC) without identifiable serous tubal intraepithelial carcinoma (STIC) within the fallopian tube (FT) occurs in approximately 50% of patients. The objective of this study was to use a multisite tumor sampling ap
Autor:
Helen M. Moore, Wendell D. Jones, Sarah R. Greytak, Jasmin H. Bavarva, Jason G. Powers, Hana Odeh, Ping Guan
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
The National Cancer Institute conducted the Biospecimen Pre-analytical Variables (BPV) study to determine the effects of formalin fixation and delay to fixation (DTF) on the analysis of nucleic acids. By performing whole transcriptome sequencing and
Autor:
Margherita Francescatto, Fujun Qiu, Jonathan Foox, Cesare Furlanello, Halil Bisgin, Daniel J. Craig, Chia Jung Chang, Kristina Giorda, Tao Chen, Sayed Mohammad Ebrahim Sahraeian, Yulong Li, Simon Cawley, Ying Yu, Zhihong Zhang, Yun-Ching Chen, Zhiguang Li, Dan Li, Vinay K. Mittal, Raymond Miller, Wendell D. Jones, Jianying Li, Marghoob Mohiyuddin, Zhining Wen, Rebecca Kusko, Gunjan Hariani, Yuanting Zheng, James C. Willey, Chen Suo, Todd Richmond, Wenzhong Xiao, Lee Scott Basehore, David P. Kreil, Dong Wang, Yutao Fu, Nikola Tom, Yifan Zhang, Zhichao Liu, Andreas Scherer, Carlos Pabón-Peña, Kira P. Grist, Meijian Guan, Giuseppe Jurman, Leihong Wu, Chang Xu, Katherine Wilkins, Jiyang Zhang, Anne Bergstrom Lucas, Barbara L. Parsons, Mehdi Pirooznia, Daniel Butler, Paweł P. Łabaj, Scott Happe, Marco Chierici, K. Miclaus, Suzy M. Stiegelmeyer, Daniel Burgess, Nathan Haseley, Kevin Lai, Weida Tong, Quan Zhen Li, Pierre R. Bushel, Donald J. Johann, Angela del Pozo, Yingyi Hao, Binsheng Gong, Guangchun Chen, Christopher E. Mason, Natalia Novoradovskaya, Joshua Xu, Tieliu Shi, Mario Solís López, Wenjun Bao, Leming Shi, J. Jasper
Publikováno v:
Genome Biology
Genome Biology, Vol 22, Iss 1, Pp 1-38 (2021)
Genome Biology, Vol 22, Iss 1, Pp 1-38 (2021)
Background Oncopanel genomic testing, which identifies important somatic variants, is increasingly common in medical practice and especially in clinical trials. Currently, there is a paucity of reliable genomic reference samples having a suitably lar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82f7a7065a20cfa1bf5bc4f2c04d890
http://hdl.handle.net/10138/337999
http://hdl.handle.net/10138/337999
Autor:
Mary Qu Yang, Dominiak N, Daniel Stetson, Rebecca Kusko, Hanane Arib, Yin L, Zhang Z, Robert Sebra, Daniel J. Craig, Todd Richmond, Natalia Novoradovskaya, Vinay K. Mittal, James C. Willey, Yaqin Zhang, Joshua Xu, Will Xiao, Leming Shi, Jennifer A. Hipp, Amelia Raymond, Weida Tong, Qiu F, Wendell D. Jones, Nikola Tom, Donald J. Johann, Dan Li, Tom Morrison, Melissa Smith, Christopher E. Mason, Jennifer S. LoCoco, Farkas Dh, Brock Je, Jiyoun Yeo, Thomas M. Blomquist, E.L. Crawford, Binsheng Gong
Clinical laboratories routinely use formalin-fixed paraffin-embedded (FFPE) tissue or cell block cytology samples in oncology panel sequencing to identify mutations that can predict patient response to targeted therapy. To understand the technical er
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e88fa5befa151c526a2db9a08258111
https://doi.org/10.1101/2021.04.06.438687
https://doi.org/10.1101/2021.04.06.438687
Autor:
Thomas Morrison, Tim R. Mercer, Nathan Haseley, Leihong Wu, Jennifer S. LoCoco, Rebecca Kusko, Quan Zhen Li, Wendell D. Jones, Daniel J. Craig, Natalia Novoradovskaya, Joshua Xu, Todd Richmond, Ira W. Deveson, Thomas M. Blomquist, Erin L. Crawford, Aminah Wali, James C. Willey, Brad Austermiller, Donald J. Johann, Guangchun Chen
Publikováno v:
SSRN Electronic Journal.
SUMMARYThe primary objective of the FDA-led Sequencing and Quality Control Phase 2 (SEQC2) project is to develop standard analysis protocols and quality control metrics for use in DNA testing to enhance scientific research and precision medicine. Thi