Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Wencui Yin"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Simvastatin (SV) is a hypolipidemic agent, and it is the 2nd most widely prescribed lipid-lowering drug. Here, the detection and characterization of SV and its metabolites was studied in selected organs/tissues (lung, liver, brain, heart and
Externí odkaz:
https://doaj.org/article/78526b5b10b64e80b6a158b6a516cb9c
Publikováno v:
Separations, Vol 9, Iss 12, p 400 (2022)
Simvastatin (SV) is a semisynthetic derivative of lovastatin (LV), which is biosynthetically produced from the fungus Aspergillus terreus and has a high log p value (log p = 4.39)and thus high hepatic extraction and high efficacy in controlling chole
Externí odkaz:
https://doaj.org/article/b2201249de404b73882289181d507954
Publikováno v:
Molecules, Vol 25, Iss 24, p 5903 (2020)
Galeon, a natural cyclic-diarylheptanoid (CDH), which was first isolated from Myrica gale L., is known to have potent cytotoxicity against A549 cell lines, anti-tubercular activity against Mycobacterium tuberculosis H37Rv, chemo-preventive potential,
Externí odkaz:
https://doaj.org/article/27263bf4914c4bd6a34b715eb683c628
Publikováno v:
Journal of Chromatography B. :125-133
Taking into consideration of the cytotoxicity and topo-IIα inhibitory activity of pyrazoline derivatives (1-3) against HCT15 cells, and known topo-IIα inhibitor, etoposide, respectively, the compounds were biotransformed in rat liver microsomes. LC
Publikováno v:
Molecules
Volume 25
Issue 24
Molecules, Vol 25, Iss 5903, p 5903 (2020)
Volume 25
Issue 24
Molecules, Vol 25, Iss 5903, p 5903 (2020)
Galeon, a natural cyclic-diarylheptanoid (CDH), which was first isolated from Myrica gale L., is known to have potent cytotoxicity against A549 cell lines, anti-tubercular activity against Mycobacterium tuberculosis H37Rv, chemo-preventive potential,
Autor:
Wencui Yin, Hyunji Jo, Adnan A. Kadi, Yurngdong Jahng, Yang Lu, Hyochang Cha, Youngjoo Kwon, Hwa Jong Lee, A. F. M. Motiur Rahman, Mohammad Sayed Alam
Publikováno v:
Archives of Pharmacal Research. 41:1131-1148
In efforts to develop effective anticancer therapeutics with greater selectivity toward cancerous cell and reduced side-effects, such as emetic effects due to detrimental action of the drug toward the intestinal flora, a series of linear diarylheptan
Publikováno v:
Journal of Chromatography B. 1054:93-104
Metabolic profiling of newly reported five topoisomerase inhibitors namely ethyl fluorescein hydrazones (EtFLHs) were studied in rat liver microsomes (RLMs) and the data were acquired in a liquid chromatography (LC) ion trap mass spectrometry. Hydrox
Publikováno v:
Journal of Chromatography B. 1054:27-35
Metabolic profiling of newly reported two topoisomerase inhibitors namely fluorescein hydrazones (FLHs) were studied in rat liver microsomes (RLMs) and the data were acquired in a liquid chromatography (LC) ion trap mass spectrometry. (E)-3',6'-dihyd
Publikováno v:
Organicbiomolecular chemistry. 15(33)
Using a short peptide precursor modified by the biaryltetrazole with intramolecular photo-click reactivity, we realized the photo-regulation of the pericellular nanofibers formed by the enzyme-instructed self-assembly on the cell membrane. Upon light
A photo-degradable supramolecular hydrogel for selective delivery of microRNA into 3D-cultured cells
Publikováno v:
Organicbiomolecular chemistry. 15(10)
Multi-functional supramolecular hydrogels have emerged as smart biomaterials for diverse biomedical applications. Here we report a multi-functional supramolecular hydrogel formed by the conjugate of the bioactive GRGDS peptide with biaryltetrazole th