Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Wencong Guo"'
Autor:
Fengjiao Pan, Ruixiao Zhang, Xuyan Liu, Xiaomeng Shi, Qing Xin, Dan Qiao, Changying Li, Yan Zhang, Mengke Chen, Wencong Guo, Shufang Luan, Leping Shao
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Background: X-linked hypophosphatemia (XLH, OMIM 307800) is a rare phosphorus metabolism disorder caused by PHEX gene variants. Many variants simply classified as missense or nonsense variants were only analyzed at the DNA level. However, growing evi
Externí odkaz:
https://doaj.org/article/645763076f2b49b2a0327a68bc254522
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
BackgroundRecent research showed that probiotics treatment may reduce insulin resistance, regulate lipid metabolism, raise liver enzyme levels, and ameliorate inflammation in individuals with metabolic associated fatty liver disease (MAFLD). However,
Externí odkaz:
https://doaj.org/article/c2bd43f4a47b40799670284f92c90b45
Autor:
Xuyan Liu, Xiaomeng Shi, Qing Xin, Zhiying Liu, Fengjiao Pan, Dan Qiao, Mengke Chen, Yiyin Zhang, Wencong Guo, Changying Li, Yan Zhang, Leping Shao, Ruixiao Zhang
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Autosomal dominant polycystic kidney disease (ADPKD) is a common monogenic multisystem disease caused primarily by mutations in the PKD1 gene or PKD2 gene. There is increasing evidence that some of these variants, which are descri
Externí odkaz:
https://doaj.org/article/f5715f55bb2b42f5894b66d609e557c4
Autor:
Qing Xin, Yameng Dong, Wencong Guo, Xiangzhong Zhao, Zhiying Liu, Xiaomeng Shi, Yanhua Lang, Leping Shao
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: Primary hyperoxaluria (PH) is a rare genetic disorder characterized by excessive accumulation of oxalate in plasma and urine, resulting in various phenotypes due to allelic and clinical heterogeneity. This study aimed to analyze the genot
Externí odkaz:
https://doaj.org/article/81ce1e6c8e6245c48f16f868a25caf23
Autor:
Xiaomeng Shi, Hong Wang, Ruixiao Zhang, Zhiying Liu, Wencong Guo, Sai Wang, Xuyan Liu, Yanhua Lang, Irene Bottillo, Bingzi Dong, Leping Shao
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 11, Iss 4, Pp n/a-n/a (2023)
Abstract Background Gitelman syndrome (GS) is a type of salt‐losing tubular disease, most of which is caused by SLC12A3 gene variants, and missense variants account for the majority. Recently, the phenomenon of exon skipping, in which variants disr
Externí odkaz:
https://doaj.org/article/7223d29c406d434eb9f28e0b160c6ccd
Autor:
Wencong Guo, Yancheng Song, Yan Sun, Huasheng Du, Yan Cai, Qingqing You, Haixia Fu, Leping Shao
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
ObjectiveDiabetic kidney disease (DKD) is the most common chronic kidney disease (CKD) and has the highest prevalence of end-stage kidney disease (ESKD) globally, owing mostly to the rise in Type 2 diabetes mellitus (T2DM) correlated with obesity. Cu
Externí odkaz:
https://doaj.org/article/5a5e48e6ef2145409c63b5878f95c5ab
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundAs a novel inflammatory marker, Systemic Immune-Inflammation Index (SII) has not been studied with hepatic steatosis. The aim of this study was to investigate the possible relationship between SII and hepatic steatosis.MethodsIn the cross-s
Externí odkaz:
https://doaj.org/article/17065693770d40bd9afa738ec965a78f
Autor:
Ruixiao Zhang, Zeqing Chen, Yanhua Lang, Shihong Shao, Yan Cai, Qingqing You, Yan Sun, Sai Wang, Xiaomeng Shi, Zhiying Liu, Wencong Guo, Yue Han, Leping Shao
Publikováno v:
Renal Failure, Vol 42, Iss 1, Pp 958-965 (2020)
Background Fabry disease (FD) is an X-linked lysosomal storage disorder caused by the mutation of the GLA gene, encoding the α-galactosidase, which is responsible for the catabolism of neutral glycosphingolipids. Microalbuminuria or low-grade protei
Externí odkaz:
https://doaj.org/article/840047d4262445f3ba65f9c3fa94869d
Autor:
Zhengxin Peng, Man Yu, Jiaming Lin, Tianqi Dong, Xiao Zhang, Mingjun Shi, Min Qin, Shasha Li, Wencong Guo, Huixia Zhang, Shuguo Sun
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100595- (2021)
Summary: Anti-PD-1/PD-L1 therapy shows long-term effects in many cancer types, but resistance and relapse remain the main limitations of this therapy. Here, we describe a protocol to evaluate the tumor response to immunotherapy in a mouse lung cancer
Externí odkaz:
https://doaj.org/article/3b8d8b7518c341a8bc6e6f972fa455d9
Autor:
Sai Wang, Yixiu Wang, Jinchao Wang, Zhiying Liu, Ruixiao Zhang, Xiaomeng Shi, Yue Han, Wencong Guo, Irene Bottillo, Leping Shao
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
BackgroundFamilial renal glucosuria is a rare renal tubular disorder caused by SLC5A2 gene variants. Most of them are exonic variants and have been classified as missense variants. However, there is growing evidence that some of these variants can be
Externí odkaz:
https://doaj.org/article/25a8d26997c04adea5cc359db013d80b