Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Wenchen Ruan"'
Autor:
Haofei Liu, Qiwen Zhao, Leyong Tan, Xin Wu, Rui Huang, Yonglin Zuo, Longjuan Chen, Jigui Yang, Zuo-Xin Zhang, Wenchen Ruan, Jiayang Wu, Fei He, Yiliang Fang, Fangyuan Mao, Peipei Zhang, Xiaoning Zhang, Peidi Yin, Zexuan Yan, Wenwen Xu, Huimin Lu, Qingrui Li, Mei Liang, Yanjun Jia, Cong Chen, Senlin Xu, Yu Shi, Yi-Fang Ping, Guang-Jie Duan, Xiao-Hong Yao, Zhijian Han, Tao Pang, Youhong Cui, Xia Zhang, Bo Zhu, Chunjian Qi, Yan Wang, Sheng-Qing Lv, Xiu-Wu Bian, Xindong Liu
Publikováno v:
Cancer Cell. 41:693-710.e8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::062bfdc9d45017863f374384b2387841
https://doi.org/10.1016/j.ccell.2023.03.004
https://doi.org/10.1016/j.ccell.2023.03.004
Autor:
Jingzi Xu, Yunjie Wang, Junru Mi, Hansen Lin, Zhengyu Cao, Tao Pang, Juan M. Saavedra, Haojie Wang, Wenchen Ruan, Zhang Luyong
Publikováno v:
Brain, Behavior, and Immunity. 89:689-691
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4ae28b7b72c8bf5bfa9c774772af8d5
https://doi.org/10.1016/j.bbi.2019.12.015
https://doi.org/10.1016/j.bbi.2019.12.015
Publikováno v:
Cellular and molecular neurobiology. 42(1)
Long non-coding RNAs (lncRNAs) can not only regulate gene transcription and translation, but also participate in the development of central nervous system diseases as epigenetic modification factors. However, their functional significance in atherosc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2fb3e9c5fde330b0026ee8b4c257300c
https://pubmed.ncbi.nlm.nih.gov/32653974
https://pubmed.ncbi.nlm.nih.gov/32653974
Autor:
Haojie Wang, Guoyin Kai, Ran Mo, Luyong Zhang, Xiao Xu, Shunyi Zhao, Tao Pang, Xin Guan, Xuechao Huang, Shiyang Shen, Wenchen Ruan
Publikováno v:
Nano letters. 20(3)
Neuroinflammation plays a pivotal part in the pathogenesis of stroke. Orphan nuclear receptor NR4A1 is involved in the inflammatory response of microglia and macrophages. In this study, we discovered an old drug, 9-aminoacridine (9-AA), as a novel NR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aceac925f8103de7b93bc8f984de75fe
https://pubmed.ncbi.nlm.nih.gov/32039606
https://pubmed.ncbi.nlm.nih.gov/32039606
Publikováno v:
Gene. 649:32-39
Long noncoding RNAs is a novel class of RNA molecules, which is closely related to the occurrence and development of human disease. Recent studies have highlighted the importance of MEG3 in angiogenesis and the maintenance of normal function of vascu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d16f6d1f568d4cf4aa38eaba8647d17c
https://doi.org/10.1016/j.gene.2018.01.072
https://doi.org/10.1016/j.gene.2018.01.072
Autor:
Haojie Wang, Yazhou Xu, Tao Pang, Luyong Zhang, Yihua Zhang, Yunjie Wang, Yun Huang, Zhangjian Huang, Juan M. Saavedra, Wenchen Ruan
Publikováno v:
Antioxidants & Redox Signaling. 28:141-163
Aims: Microglia-mediated neuroinflammation plays an important role in focal ischemic stroke, a disorder with no effective therapeutic agents. Since microglial polarization to the M2 phenot...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63309ac25f60851f3ffbdf00a9ab20d4
https://doi.org/10.1089/ars.2017.7003
https://doi.org/10.1089/ars.2017.7003
Autor:
Wenchen Ruan, Hansen Lin, Juan M. Saavedra, Yunjie Wang, Tao Pang, Haojie Wang, Jingzi Xu, Zhang Luyong, Junru Mi, Zhengyu Cao
Publikováno v:
Brain, Behavior, and Immunity. 67:101-117
Neuroinflammation plays a vital role in the pathological process of cerebral ischemic stroke, but currently there is no effective treatment. After ischemia, microglia-produced proinflammatory mediator expression contributes to the aggravation of neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf881d6401f8bbda0e7631b4e96fa70
https://doi.org/10.1016/j.bbi.2017.08.006
https://doi.org/10.1016/j.bbi.2017.08.006
Autor:
Wenchen Ruan, Guoyin Kai, Shunyi Zhao, Yunjie Wang, Xin Guan, Tao Pang, Chenglong Gao, Fei Li
Publikováno v:
Pharmacological Research. 169:105640
Aim Brain microvascular endothelial cells (BMVECs), as the important structure of blood-brain barrier (BBB), play a vital role in ischemic stroke. Pyroptosis of different cells in the brain may aggravate cerebral ischemic injury, and PGC-1α plays a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24dd80b7b950a46d07d28b2835b015f6
https://doi.org/10.1016/j.phrs.2021.105640
https://doi.org/10.1016/j.phrs.2021.105640
Publikováno v:
Acta Pharmacologica Sinica. 38:29-40
Recent studies focus on promoting neurite outgrowth to remodel the central nervous network after brain injury. Currently, however, there are few drugs treating brain diseases in the clinic by enhancing neurite outgrowth. In this study, we established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2be4bcbbfb6c9048e6a0d6fceeceac33
https://doi.org/10.1038/aps.2016.115
https://doi.org/10.1038/aps.2016.115
Publikováno v:
Acta Pharmacologica Sinica
Recent studies focus on promoting neurite outgrowth to remodel the central nervous network after brain injury. Currently, however, there are few drugs treating brain diseases in the clinic by enhancing neurite outgrowth. In this study, we established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fde82c2813f4384c0d60ef5b42e45995
https://doi.org/10.1038/s41401-019-0339-0
https://doi.org/10.1038/s41401-019-0339-0