Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Wenche Jy"'
Autor:
Ashish K. Rehni, Sunjoo Cho, Zhexuan Zhang, Priyanka Khushal, Ami P. Raval, Sebastian Koch, Miguel A. Perez-Pinzon, Weizhao Zhao, Wenche Jy, Kunjan R. Dave
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15167 (2022)
Spontaneous intracerebral hemorrhage (sICH) is a disabling stroke sub-type, and tobacco use is a prominent risk factor for sICH. We showed that chronic nicotine exposure enhances bleeding post-sICH. Reduction of hematoma growth is a promising effecti
Externí odkaz:
https://doaj.org/article/cea1dc00373f4479b2bc7e704e736697
Autor:
Wenche Jy, Ashish K. Rehni, Carlos Bidot, Hever Navarro-Quero, Conner R. Haase, Sebastian Koch, Yeon S. Ahn, Kunjan R. Dave
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Red blood cell microparticles (RMPs) is a high potency hemostatic agent, which may serve as a viable therapeutic approach. They generate thrombin in vitro and effective in arresting bleeding in animal bleeding models. However, prior to ascertaining t
Externí odkaz:
https://doaj.org/article/13fd8fb5720f407a9d91ddc79ff20c38
Autor:
Ashish K. Rehni, Sunjoo Cho, Hever Navarro Quero, Vibha Shukla, Zhexuan Zhang, Chuanhui Dong, Weizhao Zhao, Miguel A. Perez-Pinzon, Sebastian Koch, Wenche Jy, Kunjan R. Dave
Publikováno v:
Stroke. 53:3182-3191
Background: Spontaneous intracerebral hemorrhage (sICH) is the deadliest stroke subtype with no effective therapies. Limiting hematoma expansion is a promising therapeutic approach. Red blood cell-derived microparticles (RMPs) are novel hemostatic ag
Autor:
Ashish K. Rehni, Sunjoo Cho, Hever Navarro Quero, Zhexuan Zhang, Chuanhui Dong, Weizhao Zhao, Miguel A. Perez-Pinzon, Sebastian Koch, Wenche Jy, Kunjan R. Dave
Publikováno v:
Stroke. 54
Publikováno v:
Stroke. 53
Spontaneous intracerebral hemorrhage (sICH) is a subtype of hemorrhagic stroke with enormous mortality and morbidity, and tobacco use is one of the major risk factors for sICH. We have shown that red cell microparticle (RMP) treatment limits hematoma
Autor:
Carlos J. Bidot, Ashish K. Rehni, Kunjan R. Dave, Conner R. Haase, Sebastian Koch, Wenche Jy, Vibha Shukla, Yeon S. Ahn, Hever Navarro Quero, Ensign Anise A. Crane, Shivam Patel
Publikováno v:
J Cardiovasc Pharmacol Ther
Background:Uncontrollable bleeding is a major cause of mortality and morbidity worldwide. Effective hemostatic agents are urgently needed. Red cell microparticles (RMPs) are a highly promising hemostatic agent. This study evaluated the safety profile
Autor:
Sebastian Koch, Sunjoo Cho, Wenche Jy, Kunjan R. Dave, Hever Navarro Quero, Yeon S. Ahn, Miguel A. Perez-Pinzon, Ashish K. Rehni
Publikováno v:
Stroke. 51
Spontaneous intracerebral hemorrhage (sICH) is a serious form of stroke without any effective therapy. Limiting hematoma growth is a promising therapeutic strategy. Published data showed that red blood cell-derived microparticles (RMPs) enhance both
Publikováno v:
Seminars in thrombosis and hemostasis. 45(5)
Circulating cell-derived microparticles (MPs) exhibit procoagulant activity and have been investigated for a possible role in some human pathologies. However, their potential role in hemostasis has been neglected and often denied. This review brings
Autor:
Yeon S. Ahn, Miguel A. Perez-Pinzon, Kunjan R. Dave, Hever Navarro Quero, Ashish K. Rehni, Sebastian Koch, BidotCarlos, Wenche Jy, Vibha Shukla
Publikováno v:
Stroke. 50
Currently there is no effective treatment for spontaneous intracerebral hemorrhage (sICH). Limiting hematoma extension in sICH is an attractive therapeutic target. Earlier studies demonstrated that red blood cell-derived microparticles (RMP) enhance
Autor:
Orlando Gomez-Marin, Lawrence L. Horstman, Wenche Jy, Donald Williams, Anthony L. Panos, Tomas A. Salerno, Yeon S. Ahn
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 149:305-311
Objectives Improved understanding of presurgical risk factors for transfusions will lead to reduction in their number and related complications. The goal of this study is to identify these factors in coronary artery bypass graft (CABG) surgery. Metho