Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Wenbao Yu"'
Autor:
Jonathan Sussman, Abigail M Zellmer, Amy E Baxter, Rami S Vanguri, Kyung Jin Ahn, Arianne Parvaresh-Rizi, Anusha Thadi, Chia-hui Chen, Wenbao Yu, Kristina Cole, Kai Tan, Derek A Oldridge
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/280c369007684cd08ece268e9756499c
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-17 (2020)
Abstract Single-cell chromatin accessibility sequencing has become a powerful technology for understanding epigenetic heterogeneity of complex tissues. However, there is a lack of open-source software for comprehensive processing, analysis, and visua
Externí odkaz:
https://doaj.org/article/49f02ee626d44976bcbc2a722f389661
Publikováno v:
BioData Mining, Vol 11, Iss 1, Pp 1-13 (2018)
Abstract Background One strategy for addressing missing heritability in genome-wide association study is gene-gene interaction analysis, which, unlike a single gene approach, involves high-dimensionality. The multifactor dimensionality reduction meth
Externí odkaz:
https://doaj.org/article/c6cbc225992b414b8c0c661887dc35bc
Autor:
Changya Chen, Wenbao Yu, Joanna Tober, Peng Gao, Bing He, Kiwon Lee, Tuan Trieu, Gerd A. Blobel, Nancy A. Speck, Kai Tan
Publikováno v:
Cell Reports, Vol 29, Iss 12, Pp 4200-4211.e7 (2019)
Summary: Fetal hematopoietic stem cells (HSCs) undergo a developmental switch to become adult HSCs with distinct functional properties. To better understand the molecular mechanisms underlying the developmental switch, we have conducted deep sequenci
Externí odkaz:
https://doaj.org/article/5d157e929f6248ebbdbf7f9593c4eefe
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Spatial organization of the genome plays a crucial role in regulating gene expression. Here the authors introduce GMAP, the Gaussian Mixture model And Proportion test, to identify topologically associating domains and subdomains in Hi-C data.
Externí odkaz:
https://doaj.org/article/324439f719804898a27e1bc7c4641b2d
Publikováno v:
Genomics & Informatics, Vol 14, Iss 4, Pp 166-172 (2016)
Although a large number of genetic variants have been identified to be associated with common diseases through genome-wide association studies, there still exits limitations in explaining the missing heritability. One approach to solving this missing
Externí odkaz:
https://doaj.org/article/7d80997722054a308ca5ebf2f964778d
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 10, Pp 19119-19133 (2014)
miRNAs are small noncoding RNAs capable of regulating gene expression at the post-transcriptional level. A growing body of evidence demonstrated that let-7 family of miRNAs, as one of the highly conserved miRNAs, plays an important role in cell diffe
Externí odkaz:
https://doaj.org/article/c4acafd95ddb48209c558684c5b6b839
Autor:
Kai Tan, David M. Barrett, Stephan A. Grupp, Regina M. Myers, Qin Zhu, Wenbao Yu, Yasin Uzun, Yang-Yang Ding, Shovik Bandyopadhyay, Chia-Hui Chen, Peng Gao, Rajat K. Das, Changya Chen, Gregory M. Chen
The adoptive transfer of chimeric antigen receptor (CAR) T cells represents a breakthrough in clinical oncology, yet both between- and within-patient differences in autologously derived T cells are a major contributor to therapy failure. To interroga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39726f057ded0345d86aecca3e28236f
https://doi.org/10.1158/2159-8290.c.6549040.v1
https://doi.org/10.1158/2159-8290.c.6549040.v1
Autor:
Kai Tan, David M. Barrett, Stephan A. Grupp, Regina M. Myers, Qin Zhu, Wenbao Yu, Yasin Uzun, Yang-Yang Ding, Shovik Bandyopadhyay, Chia-Hui Chen, Peng Gao, Rajat K. Das, Changya Chen, Gregory M. Chen
Supplementary Table S3. Gene sets for the TCF7 regulon and interferon response. For each gene set, three annotations are provided: the Ensembl gene id, the Entrez gene id, and HGNC symbol based on annotation from Ensembl version 94.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05706ec3c32cf76c60f074124904d28
https://doi.org/10.1158/2159-8290.22539271.v1
https://doi.org/10.1158/2159-8290.22539271.v1
Autor:
Kai Tan, David M. Barrett, Stephan A. Grupp, Regina M. Myers, Qin Zhu, Wenbao Yu, Yasin Uzun, Yang-Yang Ding, Shovik Bandyopadhyay, Chia-Hui Chen, Peng Gao, Rajat K. Das, Changya Chen, Gregory M. Chen
Supplementary tables 1-4 and figures 1-11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3002eb73d2d4e6e801851a68c6307b
https://doi.org/10.1158/2159-8290.22539277
https://doi.org/10.1158/2159-8290.22539277