Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Wen-zhun Huang"'
Autor:
Xin-Fei Wang, Chang-Qing Yu, Zhu-Hong You, Yan Qiao, Zheng-Wei Li, Wen-Zhun Huang, Ji-Ren Zhou, Hai-Yan Jin
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107478- (2023)
Summary: Circular RNA (circRNA) plays an important role in the diagnosis, treatment, and prognosis of human diseases. The discovery of potential circRNA-miRNA interactions (CMI) is of guiding significance for subsequent biological experiments. Limite
Externí odkaz:
https://doaj.org/article/5bc8fd9ee3e84ca1a8b68b982a45a382
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Various biochemical functions of organisms are performed by protein–protein interactions (PPIs). Therefore, recognition of protein–protein interactions is very important for understanding most life activities, such as DNA replication and
Externí odkaz:
https://doaj.org/article/63b30bfdcc1648f492e40523cdd36dde
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 26, Iss 7, Pp 222-234 (2021)
Introduction: The prediction of interacting drug-target pairs plays an essential role in the field of drug repurposing, and drug discovery. Although biotechnology and chemical technology have made extraordinary progress, the process of dose-response
Externí odkaz:
https://doaj.org/article/528f48c859f24cd895ba5d838ded5f32
Autor:
Xin-Fei Wang, Chang-Qing Yu, Li-Ping Li, Zhu-Hong You, Wen-Zhun Huang, Yue-Chao Li, Zhong-Hao Ren, Yong-Jian Guan
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Emerging evidence has revealed that circular RNA (circRNA) is widely distributed in mammalian cells and functions as microRNA (miRNA) sponges involved in transcriptional and posttranscriptional regulation of gene expression. Recognizing the circRNA
Externí odkaz:
https://doaj.org/article/3950b2d6539f42e687414dec88e8500d
Autor:
Jie Pan, Zhu-Hong You, Li-Ping Li, Wen-Zhun Huang, Jian-Xin Guo, Chang-Qing Yu, Li-Ping Wang, Zheng-Yang Zhao
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
The prediction of protein–protein interactions (PPIs) in plants is vital for probing the cell function. Although multiple high-throughput approaches in the biological domain have been developed to identify PPIs, with the increasing complexity of PP
Externí odkaz:
https://doaj.org/article/bebfabf10dec4e30bd5fc4172f8b97f7
Autor:
Chang-Qing Yu, Xin-Fei Wang, Li-Ping Li, Zhu-Hong You, Wen-Zhun Huang, Yue-Chao Li, Zhong-Hao Ren, Yong-Jian Guan
Publikováno v:
Biology, Vol 11, Iss 9, p 1350 (2022)
Computational prediction of miRNAs, diseases, and genes associated with circRNAs has important implications for circRNA research, as well as provides a reference for wet experiments to save costs and time. In this study, SGCNCMI, a computational mode
Externí odkaz:
https://doaj.org/article/ad1b1399078c469e927a4b1e2d0b86ab
Autor:
Yu-An Huang, Zhi-An Huang, Zhu-Hong You, Zexuan Zhu, Wen-Zhun Huang, Jian-Xin Guo, Chang-Qing Yu
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
The interaction of miRNA and lncRNA is known to be important for gene regulations. However, the number of known lncRNA-miRNA interactions is still very limited and there are limited computational tools available for predicting new ones. Considering t
Externí odkaz:
https://doaj.org/article/f9defca29967410cb7c0b67106d19ea8
Publikováno v:
Plasmonics. 17:2405-2415
Publikováno v:
Plasmonics. 17:893-900
Autor:
Xin-Fei Wang, Chang-Qing Yu, Zhu-Hong You, Li-Ping Li, Wen-Zhun Huang, Zhong-Hao Ren, Yue-Chao Li, Meng-Meng Wei
Publikováno v:
Briefings in Bioinformatics. 24
Motivation A large number of studies have shown that circular RNA (circRNA) affects biological processes by competitively binding miRNA, providing a new perspective for the diagnosis, and treatment of human diseases. Therefore, exploring the potentia