Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Wen-yue Ji"'
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56395 (2013)
MicroRNA155 plays an important role in many solid malignancies. Expression and function of miR-155 in laryngeal carcinoma have not been fully understood. This study aims to investigate the expression and function of miR-155 in laryngeal squamous cell
Externí odkaz:
https://doaj.org/article/1e6eef6e6cb0465687fc64bfdbddea16
Autor:
Xue-jun Yang, Ling-hao Tang, Yi-xiang Zhang, Wen-yue Ji, Chang-hong Ma, Wan-ming Cui, Chuanchun Han
Publikováno v:
Biomedicine & Pharmacotherapy. 106:665-671
Genistein, a plant isoflavone, is reported to have therapeutic potentials in multiple cancers, However, the molecular mechanism underlying promoting cell apoptosis in laryngeal cancer remains unclear. In this study, we report that miR-1469 was induce
Publikováno v:
Oral Oncology. 48:541-546
Over-expression of DNA methyltransferase 1 (DNMT1) correlates with hypermethylation of tumor suppressor genes (TSGs) in tobacco-induced cancers. The tobacco component nitrosamine 4-(methylnitro-samino)-1-(3-pyridyl)-1-butanone (NNK) increases protein
MicroRNA-221 accelerates the proliferation of laryngeal cancer cell line Hep-2 by suppressing Apaf-1
Publikováno v:
Oncology reports. 33(3)
Laryngeal cancer is one of the most commonly occurring malignant cancers of the head and neck region. In the present study, we investigated the roles of miR-221 in laryngeal squamous cell carcinoma cell line, Hep-2. We examined the function and mecha
Publikováno v:
International journal of oncology. 44(5)
Plasma miRNAs have been reported as biomarkers for various diseases. In this study, we investigated whether plasma concentrations of miR-126 may be useful as biomarkers for laryngeal squamous cell carcinoma (LSCC). We examined the function and mechan
Publikováno v:
Oncology research. 20(10)
The present study was performed to investigate the expression of HOXA9 in human laryngeal squamous cell carcinoma and its possible roles in the progression. The levels of HOXA9 mRNA and protein were evaluated in human laryngeal squamous cell carcinom
Publikováno v:
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery. 48(8)
Publikováno v:
European Archives of Oto-Rhino-Laryngology
A novel drug named Dasatinib is a highly potent ATP-competitive orally active dual Src/Abl kinase inhibitor with anti-proliferative activity against solid tumors and CML (chronic myeloid leukaemia) cell lines. Dasatinib has been shown to have preclin
Publikováno v:
International journal of oncology. 42(2)
In the present study, we investigated the effects of the p21-activated kinase 4 (Pak4) gene on Hep-2 laryngeal carcinoma cells in vivo and in vitro. The expression of Pak4 was downregulated using small interfering RNA (siRNA). The downregulation of P
Publikováno v:
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery. 46(4)
To investigate the relationship between RASSF1A gene expression and DNA methylation or histone modification in laryngeal carcinoma tissues.Chromatin immunoprecipitation (ChIP), methylation specific polymerase chain reaction (MSP) and realtime quantit