Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Wen-tian Wang"'
Autor:
Gaijing Han, Cong Cao, Xi Yang, Guo-Wei Zhao, Xin-Jun Hu, Dong-Lin Yu, Rui-Feng Yang, Ke Yang, Ying-Ying Zhang, Wen-Tian Wang, Xiu-Zhen Liu, Peng Xu, Xue-Hui Liu, Ping Chen, Zheng Xue, De-Pei Liu, Xiang Lv
Publikováno v:
Redox Biology, Vol 50, Iss , Pp 102239- (2022)
In β-thalassemia, free α-globin chains are unstable and tend to aggregate or degrade, releasing toxic heme, porphyrins and iron, which produce reactive oxygen species (ROS). α-Hemoglobin-stabilizing protein (AHSP) is a potential modifier of β-tha
Externí odkaz:
https://doaj.org/article/64bfb4bbf354487e8dff0b3fac47b2bf
Autor:
Jian-Ping Zhang, Xin-Xin Cheng, Mei Zhao, Guo-Hua Li, Jing Xu, Feng Zhang, Meng-Di Yin, Fei-Ying Meng, Xin-Yue Dai, Ya-Wen Fu, Zhi-Xue Yang, Cameron Arakaki, Ruijun Jeanna Su, Wei Wen, Wen-Tian Wang, Wanqiu Chen, Hannah Choi, Charles Wang, Guangping Gao, Lei Zhang, Tao Cheng, Xiao-Bing Zhang
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-17 (2019)
Abstract Background Hemophilia A, a bleeding disorder resulting from F8 mutations, can only be cured by gene therapy. A promising strategy is CRISPR-Cas9-mediated precise insertion of F8 in hepatocytes at highly expressed gene loci, such as albumin (
Externí odkaz:
https://doaj.org/article/0175546634cc4b5da1856d314090ad7d
Autor:
Xiao-Bing Zhang, Kerby C. Oberg, Feng Zhang, Tao Cheng, Juan-Juan Zhao, Ya-Wen Fu, Lei Zhang, Wei Wen, Wen-Tian Wang, Jian-Ping Zhang, Zhi-Xue Yang, Xin-Yue Dai
Publikováno v:
Nucleic Acids Research
Investigations of CRISPR gene knockout editing profiles have contributed to enhanced precision of editing outcomes. However, for homology-directed repair (HDR) in particular, the editing dynamics and patterns in clinically relevant cells, such as hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc7de84eecfd97c14b89db03e47c530
https://doi.org/10.1093/nar/gkaa1251
https://doi.org/10.1093/nar/gkaa1251
Autor:
Wei Liu, Lei Zhang, Yuchen Gao, Wen-Tian Wang, Huiyuan Li, Ting Sun, Rongfeng Fu, Xiaofan Liu, Mankai Ju, Yuan Zhou, Xin-Yue Dai, Yueting Huang, Lihong Shi, Ying Ch, Huan Dong, Wenjing Gu, Renchi Yang
Publikováno v:
Haematologica
The role of the bone marrow niche in essential thrombocythemia (ET) remains unclear. Here, we observed multilevel defects in the hematopoietic niche of patients with JAK2V617F-positive ET, including functional deficiency in mesenchymal stromal cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::472b4fb4b330184b83dda3cd8783ec6d
http://europepmc.org/articles/PMC7049349
http://europepmc.org/articles/PMC7049349
Publikováno v:
Biochemical and Biophysical Research Communications. 521:326-332
Hematopoiesis is systematically regulated by microenvironmental factors. The positive and negative factors coordinated together to yield a complicated blood system. Interferon-γ (IFNγ) has been identified as a common cause of various hematopoietic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d97fcfe984ee6c5a881559180b8fc056
https://doi.org/10.1016/j.bbrc.2019.10.068
https://doi.org/10.1016/j.bbrc.2019.10.068
Autor:
Tao Cheng, Xin-Yue Dai, Guo-Hua Li, Xin-Xin Cheng, Fei-Ying Meng, Wen-Tian Wang, Feng Zhang, Jian-Ping Zhang, Ruijun Jeanna Su, Guangping Gao, Wanqiu Chen, Zhi-Xue Yang, Wei Wen, Jing Xu, Hannah Choi, Meng-Di Yin, Charles Wang, Xiao-Bing Zhang, Cameron Arakaki, Ya-Wen Fu, Lei Zhang, Mei Zhao
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-17 (2019)
Genome Biology
Genome Biology
Background Hemophilia A, a bleeding disorder resulting from F8 mutations, can only be cured by gene therapy. A promising strategy is CRISPR-Cas9-mediated precise insertion of F8 in hepatocytes at highly expressed gene loci, such as albumin (Alb). Unf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec7d067ef4ed93caf644a5f740f8148
https://doaj.org/article/0175546634cc4b5da1856d314090ad7d
https://doaj.org/article/0175546634cc4b5da1856d314090ad7d
Publikováno v:
AOPC 2021: Optical Sensing and Imaging Technology.
Remote sensing image combines the characteristics of visible light image, infrared image and other multi-spectral images, making it rich in details and low resolution. However, due to factors such as weather and transmission errors, salt and pepper n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a186cd546b19dfaa76cafee35df65e4
https://doi.org/10.1117/12.2606568
https://doi.org/10.1117/12.2606568
Publikováno v:
AOPC 2021: Optical Sensing and Imaging Technology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fd17e0e62d9717437fba827c3e6d33c
https://doi.org/10.1117/12.2606564
https://doi.org/10.1117/12.2606564
Autor:
Gaijing Han, Cong Cao, Xi Yang, Guo-Wei Zhao, Xin-Jun Hu, Dong-Lin Yu, Rui-Feng Yang, Ke Yang, Ying-Ying Zhang, Wen-Tian Wang, Xiu-Zhen Liu, Peng Xu, Xue-Hui Liu, Ping Chen, Zheng Xue, De-Pei Liu, Xiang Lv
Publikováno v:
Redox Biology, Vol 50, Iss, Pp 102239-(2022)
In β-thalassemia, free α-globin chains are unstable and tend to aggregate or degrade, releasing toxic heme, porphyrins and iron, which produce reactive oxygen species (ROS). α-Hemoglobin-stabilizing protein (AHSP) is a potential modifier of β-tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d264e38265c1e484054facab0024f353
https://pubmed.ncbi.nlm.nih.gov/35092867
https://pubmed.ncbi.nlm.nih.gov/35092867
Publikováno v:
Zhongguo shi yan xue ye xue za zhi. 28(1)
To investigate the effects of IRF1 on the homeostasis and differentiation of K562 cells.Three different vectors were constructed to screen the best strategy for IRF1 overexpression. The effect of IRF1 on cell proliferation and apoptosis was explored
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5931b3fd85487cb651c7de75df659b3c
https://pubmed.ncbi.nlm.nih.gov/32027252
https://pubmed.ncbi.nlm.nih.gov/32027252