Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Wen-tao DENG"'
Autor:
Emily R. Sechrest, Robert J. Barbera, Xiaojie Ma, Frank Dyka, Junyeop Ahn, Brooke A. Brothers, Marion E. Cahill, Isaac Hall, Wolfgang Baehr, Wen-Tao Deng
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Long-and middle-wavelength cone photoreceptors, which are responsible for our visual acuity and color vision, comprise ~95% of our total cone population and are concentrated in the fovea of our retina. Previously, we characterized the disease mechani
Externí odkaz:
https://doaj.org/article/27eff3ca2dcf4130af51a1fa998a45e7
Autor:
Celine Brooks, Douglas Kolson, Emily Sechrest, Janelle Chuah, Jane Schupp, Neil Billington, Wen-Tao Deng, David Smith, Maxim Sokolov
Publikováno v:
PLoS ONE, Vol 19, Iss 10, p e0308058 (2024)
Neurodegenerative diseases are characterized by the presence of misfolded and aggregated proteins which are thought to contribute to the development of the disease. In one form of inherited blinding disease, retinitis pigmentosa, a P23H mutation in t
Externí odkaz:
https://doaj.org/article/bbae70956c7444609e93ae590e85223d
Autor:
Boyuan Yan, Suresh Viswanathan, Scott E. Brodie, Wen-Tao Deng, Kirsten E. Coleman, William W. Hauswirth, Sheila Nirenberg
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 406-417 (2023)
Optogenetic gene therapies offer a promising strategy for restoring vision to patients with retinal degenerative diseases, such as retinitis pigmentosa (RP). Several clinical trials have begun in this area using different vectors and optogenetic prot
Externí odkaz:
https://doaj.org/article/7c6b4f3a22b54425a4e36725bb472ee2
Autor:
Sechrest, Emily R., Barbera, Robert J., Xiaojie Ma, Dyka, Frank, Junyeop Ahn, Brothers, Brooke A., Cahill, Marion E., Hall, Isaac, Baehr, Wolfgang, Wen-Tao Deng
Publikováno v:
Frontiers in Neuroscience; 2024, p01-10, 10p
Publikováno v:
Fayixue Zazhi, Vol 33, Iss 6, Pp 651-656 (2017)
Externí odkaz:
https://doaj.org/article/d387a2fa526444f4b580d9f3bde84d71
Autor:
Yuxin Zhang, Wen-Tao Deng, Wei Du, Ping Zhu, Jie Li, Fan Xu, Jingfen Sun, Cecilia D. Gerstner, Wolfgang Baehr, Sanford L. Boye, Chen Zhao, William W. Hauswirth, Ji-jing Pang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Cones are responsible for daylight, central, high acuity and color vision. Three proteins found in human cones, i.e. long-wavelength (L)-, middle-wavelength (M)-, and short-wavelength sensitive (S)-opsins, are responsible for red, green and
Externí odkaz:
https://doaj.org/article/bc27d7c6a496437cb3861b2557b98e8d
Autor:
Xiajie Ma, Emily R. Sechrest, Diego Fajardo, Ping Zhu, Frank Dyka, Yixiao Wang, Ekaterina Lobanova, Shannon E. Boye, Wolfgang Baehr, Wen-Tao Deng
Publikováno v:
Hum Gene Ther
Blue cone monochromacy (BCM) is a congenital vision disorder affecting both middle-wavelength (M) and long-wavelength (L) cone photoreceptors of the human retina. BCM results from abolished expression of green and red light-sensitive visual pigments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa141c94b893e4ed4459bbaa0a50fc10
https://doi.org/10.1089/hum.2021.298
https://doi.org/10.1089/hum.2021.298
Autor:
Ya-ke REN, Xue-qian LÜ, Zu-ming LIU, Bing WEI, Ting LEI, Quan LI, Xiao-bo JI, Wen-tao DENG, Yong-kang AI
Publikováno v:
Transactions of Nonferrous Metals Society of China. 32:2276-2289
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::933f3393103e4ac73c15c60e18a0ea48
https://doi.org/10.1016/s1003-6326(22)65947-8
https://doi.org/10.1016/s1003-6326(22)65947-8
Publikováno v:
Fayixue Zazhi, Vol 33, Iss 6, Pp 687-689 (2017)
Externí odkaz:
https://doaj.org/article/98c0bcead1ae4922aa706edfc66f2e32
Autor:
Wen-Tao Deng, Saravanan Kolandaivelu, Astra Dinculescu, Jie Li, Ping Zhu, Vince A. Chiodo, Visvanathan Ramamurthy, William W. Hauswirth
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Rod and cone phosphodiesterase 6 (PDE6) are key effector enzymes of the vertebrate phototransduction pathway. Rod PDE6 consists of two catalytic subunits PDE6α and PDE6β and two identical inhibitory PDE6γ subunits, while cone PDE6 is composed of t
Externí odkaz:
https://doaj.org/article/a42a25a1fdca42c4837639e5129d7603