Výsledky vyhledávání

Design, synthesis and anti-tumor activity studies of novel pyrido[3, 4-d]pyrimidine derivatives

Autor: Wen-Ge Guo, Jun-Ru Zhao, Min Li, Ting Hu, Zengyangzong Dan, Qian Zhang, Li-Ying Ma, Sai-Yang Zhang, Bing Zhao

Publikováno v: Bioorganicmedicinal chemistry letters. 76

In order to find high-efficiency and low-toxic anti-tumor drugs, 29 pyrido[3,4-d]pyrimidine compounds were designed, synthesized and evaluated by MTT assay in vitro. The results presented that most of the compounds had good antitumor activities, amon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77cf163758cb105db1b9b2e6eea4b316
https://pubmed.ncbi.nlm.nih.gov/36216031

Zobrazit plný text záznamu

Design, synthesis and preliminary biological evaluation of new [1,2,3]triazolo[4,5-d]pyrimidine/thiourea hybrids as antiproliferative agents

Autor: Bin Yu, Xue-Qi Liu, Peng-Fei Geng, Zhong-Hua Li, Tao-Qian Zhao, Hong-Min Liu, Wen-Ge Guo

Publikováno v: European journal of medicinal chemistry. 139

A series of new [1,2,3]triazolo[4,5- d ]pyrimidine/thiourea hybrids were designed and synthesized through the scaffold replacement/ring cleavage strategy. SARs studies revealed that the N -heteroarene moiety attached to the thiourea is preferred over

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce5e1b3f8d1b380068ea79a0271534d3
https://pubmed.ncbi.nlm.nih.gov/28863355

Zobrazit plný text záznamu

Design, synthesis and biological evaluation of [1,2,3]triazolo[4,5-d]pyrimidine derivatives possessing a hydrazone moiety as antiproliferative agents

Autor: Hong-Min Liu, Bing Zhao, Biao Hu, Li-Ying Ma, Zhong-Hua Li, Bin Yu, Qian Guo, Peng-Fei Geng, Dongxiao Yang, Xin-Hui Zhang, Ji Zhang, Hao-Ming Wei, Wen-Ge Guo

Publikováno v: European journal of medicinal chemistry. 124

A series of [1,2,3]triazolo[4,5-d]pyrimidine derivatives bearing a hydrazone moiety were designed, synthesized and evaluated for their antiproliferative activity against several cancer cell lines of different origins by MTT assay. Most of the synthes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be70401defb031125529133c4b15f366
https://pubmed.ncbi.nlm.nih.gov/27771599

Zobrazit plný text záznamu

High expression of S100A8 gene is associated with drug resistance to etoposide and poor prognosis in acute myeloid leukemia through influencing the apoptosis pathway

Autor: Chien-Shing Chen, Ye Zhao, Zi-Xing Chen, Jiannong Cen, Shuiyan Wu, Ming-ying Zhang, Qi Zhou, Wen-ge Guo, Shaoyan Hu, Jian Pan, Wen-hua Yan, Weiying Gu, Xiao-yan Yang

Publikováno v: OncoTargets and therapy

Xiao-yan Yang,1,* Ming-ying Zhang,1,* Qi Zhou,1 Shui-yan Wu,1 Ye Zhao,2 Wei-ying Gu,3 Jian Pan,1 Jian-nong Cen,2 Zi-xing Chen,2 Wen-ge Guo,4 Chien-shing Chen,5 Wen-hua Yan,6 Shao-yan Hu1 1Department of Haematology and Oncology, Children’s Hospital

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1cc65fc27db976a385291dfd719f7d0
https://www.dovepress.com/high-expression-of-s100a8-gene-is-associated-with-drug-resistance-to-e-peer-reviewed-article-OTT

Zobrazit plný text záznamu

Application of Thrust Force Model in GEO’s Orbit Determination in Case of Maneuvers

Autor: Jun-Li Zhang, Hong-Xing Qiu, Wen-Ge Guo, Yong Yang

Publikováno v: Lecture Notes in Electrical Engineering ISBN: 9783642374067

GEO satellites play a significant role in COMPASS satellite navigation system. The GEO’s orbit must be maneuvered periodically for station-keeping. The method of the maneuvering orbit determination and prediction must be studied for advancing the C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3413ae64d55d9f5117aa5d24c0f9dc52
https://doi.org/10.1007/978-3-642-37407-4_5

Zobrazit plný text záznamu

Study of Determination Orbit of COMPASS-GEO After Maneuvers with Short Segmental Arc

Autor: Wen-Ge Guo, Hong-Xing Qiu, Jun-Li Zhang, Yong Yang

Publikováno v: Lecture Notes in Electrical Engineering ISBN: 9783642374067

The GEO satellite must be maneuvered periodically for station-keeping due to its particular orbit. How to realize rapid orbit determination and prediction after orbit maneuver of GEO and shorten the orbit recovery time must be studied for COMPASS nav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a4ae19ffc5c792f8537a1baf4bf75b25
https://doi.org/10.1007/978-3-642-37407-4_6

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání