Výsledky vyhledávání - "Wen-cong Liu"

Akademický článek

Fast and Sensitive LC-DAD-ESI/MS Method for Analysis of Saikosaponins c, a, and d from the Roots of Bupleurum Falcatum (Sandaochaihu)

Autor: Jian Liang, Yi-Nan Zheng, Yu-Fang He, Xiao-Hua Li, Zi Wang, Li-Chun Zhao, Wen-Cong Liu, Wei Li

Publikováno v: Molecules, Vol 16, Iss 2, Pp 1533-1543 (2011)

In the present study, we developed a liquid chromatography-diode array detector-electrospray ionization/mass spectrometric (LC-DAD-ESI/MS) method for analysis of saikosaponins in Bupleurum falcatum. The LC method employed a ZORBAX SB-Aq analytical co

Externí odkaz: https://doaj.org/article/fe64d766544241559d9ad236fb4676b3

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Endoplasmic Reticulum Stress-Activated PERK-eIF2α-ATF4 Signaling Pathway is Involved in the Ameliorative Effects of Ginseng Polysaccharides against Cisplatin-Induced Nephrotoxicity in Mice

Autor: Shi-Han Wang, Xiao-Meng Wei, Rui Zhang, Shan-Shan Li, Li Wei, Ying-Ping Wang, Yin-Shi Sun, Shuang Jiang, Wen-cong Liu, Wang Zi

Publikováno v: ACS Omega, Vol 6, Iss 13, Pp 8958-8966 (2021)
ACS Omega

Although previous studies have reported that saponins (ginsenosides, the major active and most representative ingredients in Panax ginseng C.A. Meyer) exerted a good ameliorative effect on cisplatin (CP)-induced acute kidney injury in animal models,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f9a36d4eb3c7e90d0864752943f148
https://doaj.org/article/08c4b791ce5c4381804743b9102c95b1

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α-Mangostin, a Dietary Xanthone, Exerts Protective Effects on Cisplatin-Induced Renal Injury via PI3K/Akt and JNK Signaling Pathways in HEK293 Cells

Autor: Wen-cong Liu, Wei Li, Yu-Fang He, Li Xindian, Xiao-Tong Yan, Qiong Li, Shuang Jiang, Wang Zi, Shen Ren, Li-Chun Zhao

Publikováno v: ACS Omega, Vol 5, Iss 32, Pp 19960-19967 (2020)
ACS Omega

Previous report has confirmed the beneficial effects of α-mangostin (α-MG), a major and representative xanthone distributed in mangosteen (Garcinia mangostana) on the cisplatin-induced rat model. However, the molecular mechanisms related to its ren

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8974285cc70be945751d477287e4ecad
https://doi.org/10.1021/acsomega.0c01121

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Alleviative effects of 20(R)-Rg3 on HFD/STZ-induced diabetic nephropathy via MAPK/NF-κB signaling pathways in C57BL/6 mice

Autor: Xiang-Hui Lin, Xiao-jie Gong, Ying-Ping Wang, Wei Li, Zhi Liu, Ying Li, Jun-nan Hu, Jin-Gang Hou, Wen-cong Liu, Zi Wang

Publikováno v: Journal of ethnopharmacology. 267

Ethnopharmacological relevance Diabetic nephropathy (DN) is a major complication of diabetes. The kidney disease develops in nearly 20%–40% of type 2 diabetes (T2D) patients. Ginseng is the root of Panax ginseng C. A. Meyer and has been used in pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::756ae39d851efd0469cad8289ea5bcf4
https://pubmed.ncbi.nlm.nih.gov/33091499

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Ginsenoside Rb3 provides protective effects against cisplatin‐induced nephrotoxicity via regulation of AMPK‐/mTOR‐mediated autophagy and inhibition of apoptosis in vitro and in vivo

Autor: Jing-jing Xing, Ying-Ping Wang, Wen-cong Liu, Chen Chen, Jin-Gang Hou, Zhi-na Ma, Wei Li, Shen Ren, Zi Wang

Publikováno v: Cell Proliferation

Objectives: Based on previous reports that ginsenosides have been shown to exert better preventive effects on cisplatin‐induced kidney injury, the present work aims to evaluate the protective effects of ginsenoside Rb3 (G‐Rb3) on cisplatin‐indu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c3b11e320bb0f16f45d8c1b131f131
https://doi.org/10.1111/cpr.12627

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Arginyl-fructosyl-glucose, a Major Maillard Reaction Product of Red Ginseng, Attenuates Cisplatin-Induced Acute Kidney Injury by Regulating Nuclear Factor κB and Phosphatidylinositol 3-Kinase/Protein Kinase B Signaling Pathways

Autor: Wei-Zhe Zhang, Rong-Yan Li, Xiao-Tong Yan, Wen-cong Liu, Wei Li, Chen Chen, Zi Wang, Ding Chuanbo, Yue-Ru Li, Jin-Gang Hou, Yinan Zheng

Publikováno v: Journal of agricultural and food chemistry. 67(20)

Recently, although ginseng ( Panax ginseng C. A. Meyer) and its main component saponins (ginsenosides) have been reported to exert protective effects on cisplatin (CDDP)-induced acute kidney injury (AKI), the beneficial activities of non-saponin on C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5afe6f50755bc4e73056e22c08d1057
https://pubmed.ncbi.nlm.nih.gov/31045365

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Caspase-Mediated Anti-Apoptotic Effect of Ginsenoside Rg5, a Main Rare Ginsenoside, on Acetaminophen-Induced Hepatotoxicity in Mice

Autor: Wen-cong Liu, Meng-han Yan, Zi Wang, Jun-nan Hu, Wei Li, Jing-jing Xing

Publikováno v: Journal of agricultural and food chemistry. 65(42)

Frequent overdose of acetaminophen (APAP) is one of the most common and important incentives of acute hepatotoxicity. Prior to this work, our research group confirmed that black ginseng (Panax ginseng, BG) showed powerful protective effects on APAP-i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3def1540ad5df45baf763918995de107
https://pubmed.ncbi.nlm.nih.gov/28965396

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