Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Wen-bing Jin"'
Autor:
Shushan Sargsian, Octavio Mondragón-Palomino, Alannah Lejeune, Defne Ercelen, Wen-Bing Jin, Alan Varghese, Yvonne A. L. Lim, Chun-Jun Guo, P’ng Loke, Ken Cadwell
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-17 (2024)
Abstract Background Parasitic helminths influence the composition of the gut microbiome. However, the microbiomes of individuals living in helminth-endemic regions are understudied. The Orang Asli, an indigenous population in Malaysia with high burde
Externí odkaz:
https://doaj.org/article/acc61c8d0cf043ae85aaf58f97e2fbfd
Autor:
Wen‐Bing Jin, Chun‐Jun Guo
Publikováno v:
iMeta, Vol 3, Iss 4, Pp n/a-n/a (2024)
Abstract Hundreds of microbiota gene expressions are significantly different between healthy and diseased humans. The “bottleneck” preventing a mechanistic dissection of how they affect host biology/disease is that many genes are encoded by nonmo
Externí odkaz:
https://doaj.org/article/2e734eeae3f64cf68f87a604685f5601
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
The biosynthesis of the antitumour antibiotic CC-1065 includes formation of a cyclopropane. Here, the authors identify the two enzymes that work together to catalyze this reaction, a radical S-adenosyl-l-methionine enzyme and a methyltransferase, and
Externí odkaz:
https://doaj.org/article/edcd713c52a44ba79dc899e965e8716e
Autor:
Hua Yuan, Jinru Zhang, Yujuan Cai, Sheng Wu, Kui Yang, H. C. Stephen Chan, Wei Huang, Wen-Bing Jin, Yan Li, Yue Yin, Yasuhiro Igarashi, Shuguang Yuan, Jiahai Zhou, Gong-Li Tang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
GyrI-like proteins are small-molecule binding proteins that are widely distributed in prokaryotes and eukaryotes, with functions that are poorly characterized. Here, the authors identify GyrI-like proteins as cyclopropanoid cyclopropyl hydrolases tha
Externí odkaz:
https://doaj.org/article/266a1355c538408382157a4388d51a1c
Autor:
Wen-bing Jin, Chun-Jun Guo
Publikováno v:
Synthetic and Systems Biotechnology, Vol 5, Iss 1, Pp 35-36 (2020)
Externí odkaz:
https://doaj.org/article/1b5937f260f34bfb8af316fea05767bc
Autor:
John Hambor, Lance Chou, Randy S. Longman, Monica Viladomiu, Wen-Bing Jin, Svetlana Lima, Su-Ellen Brown, Chun-Jun Guo, Vinita Jacob, Silvia Pires, Ylaine Gerardin, Gregory G. Putzel, Carl V. Crawford, Ellen Scherl, Lasha Gogokhia
Publikováno v:
Gastroenterology
Background & Aims Fecal microbiota transplantation (FMT) is an emerging treatment modality for ulcerative colitis (UC). Several randomized controlled trials have shown efficacy for FMT in the treatment of UC, but a better understanding of the transfe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32fe7de9853f81541a1a9a714e9c448
https://doi.org/10.1053/j.gastro.2021.09.061
https://doi.org/10.1053/j.gastro.2021.09.061
Autor:
Krishna Kadaveru, John Hambor, Clarissa Campbell, Alexander Y. Rudensky, Cheryl Mai, Daniel Konstantinovsky, Peter T. McKenney, Ruben J. Ramos, Olga I Isaeva, Chun-Jun Guo, Michail Schizas, Justin R. Cross, Jacob Verter, Wen-Bing Jin, Sara Violante
Publikováno v:
Nature. 581:475-479
Intestinal health relies on the immunosuppressive activity of CD4+ regulatory T (Treg) cells1. Expression of the transcription factor Foxp3 defines this lineage, and can be induced extrathymically by dietary or commensal-derived antigens in a process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ba5447a9b51cd120c59b91735e0d748
https://doi.org/10.1038/s41586-020-2193-0
https://doi.org/10.1038/s41586-020-2193-0
Autor:
Wen Zhang, Mengze Lyu, Nicholas J. Bessman, Zili Xie, Mohammad Arifuzzaman, Hiroshi Yano, Christopher N. Parkhurst, Coco Chu, Lei Zhou, Gregory G. Putzel, Ting-Ting Li, Wen-Bing Jin, Jordan Zhou, Hongzhen Hu, Amy M. Tsou, Chun-Jun Guo, David Artis
Publikováno v:
Cell. 185:4170-4189.e20
Nociceptive pain is a hallmark of many chronic inflammatory conditions including inflammatory bowel diseases (IBDs); however, whether pain-sensing neurons influence intestinal inflammation remains poorly defined. Employing chemogenetic silencing, ade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d32de5ff473f2d012b08634331e49545
https://doi.org/10.1016/j.cell.2022.09.008
https://doi.org/10.1016/j.cell.2022.09.008
Autor:
Mohammad, Arifuzzaman, Tae Hyung, Won, Ting-Ting, Li, Hiroshi, Yano, Sreehaas, Digumarthi, Andrea F, Heras, Wen, Zhang, Christopher N, Parkhurst, Sanchita, Kashyap, Wen-Bing, Jin, Gregory Garbès, Putzel, Amy M, Tsou, Coco, Chu, Qianru, Wei, Alex, Grier, Stefan, Worgall, Chun-Jun, Guo, Frank C, Schroeder, Samantha, Jensen
Publikováno v:
Nature. 611(7936)
Dietary fibres can exert beneficial anti-inflammatory effects through microbially fermented short-chain fatty acid metaboliteslt;supgt;1,2lt;/supgt;, although the immunoregulatory roles of most fibre diets and their microbiota-derived metabolites rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::15d1ee90538b189fc230e8e55b5af4d4
https://pubmed.ncbi.nlm.nih.gov/36323778
https://pubmed.ncbi.nlm.nih.gov/36323778
Autor:
Svetlana Ferreira Lima, Amanda Rupert, Monica Viladomiu, Andrew Marderstein, Silvia Pires, Gregory Putzel, Viola Woo, Gabriela Funez-dePagnier, Wen-Bing Jin, Chun-Jun Guo, Ellen Scherl, Randy S. Longman
Publikováno v:
The Journal of Immunology. 208:174.01-174.01
Joint inflammation (spondyloarthritis, SpA), is the most common extra-intestinal manifestation of inflammatory bowel disease (IBD), but the specific role for therapies targeting SpA is not well defined. Sulfasalazine (SAS) is a prodrug composed of tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4240517319b80ac603d46fd447c56604
https://doi.org/10.4049/jimmunol.208.supp.174.01
https://doi.org/10.4049/jimmunol.208.supp.174.01