Zobrazeno 1 - 10
of 17 812
pro vyhledávání: '"Wen-an Wang"'
Autor:
Yanxian Ren, Pengfei Yang, Chenghao Li, Wen-an Wang, Tianyi Zhang, Jin Li, Haining Li, Chunlu Dong, Wenbo Meng, Heng Zhou
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Radiotherapy is an important cancer treatment strategy that causes DNA damage in tumor cells either directly or indirectly. Autophagy is a physiological process linked to DNA damage. Mitophagy is a form of autophagy, which specifically targe
Externí odkaz:
https://doaj.org/article/6dd5bc9e8b6248f4bbb3fcf681ca80a0
Autor:
Amado Carreras-Sureda, Laurence Abrami, Kim Ji-Hee, Wen-An Wang, Christopher Henry, Maud Frieden, Monica Didier, F Gisou van der Goot, Nicolas Demaurex
Publikováno v:
eLife, Vol 10 (2021)
Efficient immune responses require Ca2+ fluxes across ORAI1 channels during engagement of T cell receptors (TCR) at the immune synapse (IS) between T cells and antigen presenting cells. Here, we show that ZDHHC20-mediated S-acylation of the ORAI1 cha
Externí odkaz:
https://doaj.org/article/ad6d37568ea5409c901775a30f909b1b
Publikováno v:
Cells, Vol 11, Iss 11, p 1722 (2022)
Calreticulin is an endoplasmic Ca2+ binding protein and molecular chaperone. As a cardiac embryonic gene, calreticulin is essential for heart development. The protein supports Ca2+-dependent signaling events that are critical to cardiomyocyte differe
Externí odkaz:
https://doaj.org/article/9d7bf7d70d934b4786785f928cbf1556
Autor:
Wen-An Wang, Wen-Xin Liu, Serpen Durnaoglu, Sun-Kyung Lee, Jihong Lian, Richard Lehner, Joohong Ahnn, Luis B. Agellon, Marek Michalak
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract A direct link between Ca2+ and lipid homeostasis has not been definitively demonstrated. In this study, we show that manipulation of ER Ca2+ causes the re-distribution of a portion of the intracellular unesterified cholesterol to a pool that
Externí odkaz:
https://doaj.org/article/181ac3ffb8594bf0b12bfef6d8cefed5
Autor:
Chih-Hsiung Hsieh, Pei-Shiuan Ho, Wen-Lun Wang, Fu-Hsuan Shih, Chen-Tai Hong, Pei-Wen Wang, Dar-Bin Shieh, Wei-Lun Chang, Yi-Ching Wang
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-18 (2024)
Abstract Background Stromal fibrosis is highly associated with therapeutic resistance and poor survival in esophageal squamous cell carcinoma (ESCC) patients. Low expression of plasma gelsolin (pGSN), a serum abundant protein, has been found to corre
Externí odkaz:
https://doaj.org/article/91f79a3af5354b18b038a5a565c91bb0
Autor:
Min Yang, Jing Ge, Yu-Lian Liu, Huan-Yu Wang, Zhi-Han Wang, Dan-Pei Li, Rui He, Yu-Yu Xie, Hong-Yan Deng, Xue-Min Peng, Wen-She Wang, Jia-Dai Liu, Zeng-Zhe Zhu, Xue-Feng Yu, Pema Maretich, Shingo Kajimura, Ru-Ping Pan, Yong Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Beige fat activation involves a fuel switch to fatty acid oxidation following chronic cold adaptation. Mitochondrial acyl-CoA synthetase long-chain family member 1 (ACSL1) localizes in the mitochondria and plays a key role in fatty acid oxid
Externí odkaz:
https://doaj.org/article/35f6336cc18f4ad4a0ac9089445e2439
Autor:
Hui Shi, Junjie Yin, Zhangjie Zhao, Hong Yu, Hong Yi, Li Xu, Huimin Tong, Min He, Xiaobo Zhu, Xiang Lu, Qing Xiong, Weitao Li, Yongyan Tang, Qingqing Hou, Li Song, Long Wang, Xiaoqiong Chen, Changhui Sun, Ting Li, Jing Fan, Yan Li, Peng Qin, Wen-Ming Wang, Shigui Li, Xuewei Chen, Jiayang Li, Jing Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The Ideal Plant Architecture 1 (IPA1) transcription factor promotes rice yield and immunity through phosphorylation at its amino acid residue Ser163 as a switch. Although phosphorylated IPA1 mimic, IPA1(S163D), directly targets the promoter
Externí odkaz:
https://doaj.org/article/5d31f0514afe434d988481c6fa60b2c7
Autor:
WEN Yan, WANG Yulan
Publikováno v:
口腔疾病防治, Vol 32, Iss 9, Pp 730-736 (2024)
Bacterial overproliferation and virulence factors in plaque biofilms can cause inflammation of soft and hard tissues around the implant, resulting in peri-implantitis. If not well controlled, severe peri-implantitis can lead to failure of implant oss
Externí odkaz:
https://doaj.org/article/3aadc7ab1d044f0fb05a11f8f1a15b73
Autor:
Yu-Hsien Lin, Yu-Tsung Lin, Yun-Che Wu, Wen-Chien Wang, Kun-Hui Chen, Chien-Chou Pan, Cheng-Hung Lee, Shun-Fa Yang, Jun-Sing Wang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract To investigate the relationship between preoperative blood glucose levels and long-term all-cause mortality in patients with osteoporotic vertebral compression fractures (OVCF) who underwent percutaneous vertebroplasty (VP). This single-cent
Externí odkaz:
https://doaj.org/article/5354110bcf0c4ab7b95f1f636eb1492e
Autor:
Rong-Hsuan Wang, Pin-Ru Chen, Yue-Ting Chen, Yi-Chang Chen, Yu-Hsin Chu, Chia-Chen Chien, Po-Chen Chien, Shao-Yun Lo, Zhong-Liang Wang, Min-Chen Tsou, Ssu-Yu Chen, Guang-Shen Chiu, Wen-Ling Chen, Yi-Hsuan Wu, Lily Hui-Ching Wang, Wen-Ching Wang, Shu-Yi Lin, Hsing-Jien Kung, Lu-Hai Wang, Hui-Chun Cheng, Kai-Ti Lin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Most cancer cells reprogram their glucose metabolic pathway from oxidative phosphorylation to aerobic glycolysis for energy production. By reducing enzyme activity of pyruvate kinase M2 (PKM2), cancer cells attain a greater fraction of glyco
Externí odkaz:
https://doaj.org/article/11ac430e3387400d8e564c205164f273