Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Wen-Yan Wang"'
Publikováno v:
Zhipu Xuebao, Vol 45, Iss 5, Pp 666-672 (2024)
Inflammation can occur at any time in many diseases, and affect the activity of metabolism enzymes and transporters, so change the blood concentration and therapeutic effect of therapeutic drugs. Therefore, it is necessary to study the metabolic chan
Externí odkaz:
https://doaj.org/article/30d8b55137144100bcbb3a0ffbf6ce7c
Autor:
Lei Zhan, Jing Zhang, Jun-Hui Zhang, Xiao-Jing Liu, Bao Guo, Jia-Hua Chen, Zhen-Hai Tang, Wen-Yan Wang, Qing-Yuan Wang, Bing Wei, Yun-Xia Cao
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-5 (2023)
Abstract Background N6-methyladenosine (m6A) methylation is the most abundant chemical posttranscriptional modification of mRNA, and it is associated with the regulation of the immune response to tumors. However, the function of m6A modification in t
Externí odkaz:
https://doaj.org/article/b68b3202e28d4ea982f1f074e697d05f
NLRC5 potentiates anti-tumor CD8+ T cells responses by activating interferon-β in endometrial cancer
Autor:
Jing Zhang, Bao Guo, Jia-Hua Chen, Xiao-Jing Liu, Jun-Hui Zhang, Hai-Qing Zhu, Wen-Yan Wang, Zhen-Hai Tang, Bing Wei, Yun-Xia Cao, Lei Zhan
Publikováno v:
Translational Oncology, Vol 36, Iss , Pp 101742- (2023)
Objectives: NLR family CARD domain containing 5 (NLRC5) could promote major histocompatibility complex class I (MHC-I)-dependent CD8+ T cell-mediated anticancer immunity. In this study, the immunosurveillance role and underlying mechanisms of NLRC5 i
Externí odkaz:
https://doaj.org/article/1fe009f5924d4389b7cd3090393e42fc
Autor:
Dai Cao, Die Chen, Jiang-Nan Xia, Wen-Yan Wang, Guo-Yuan Zhu, Li-Wen Chen, Chuantao Zhang, Bo Tan, Hui Li, Ying-Wei Li
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 155, Iss , Pp 113705- (2022)
Lung cancer is the leading cause of cancer-related death worldwide. The development of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) and immune checkpoint inhibitors (ICIs) has brought favorable survival benefits to patients
Externí odkaz:
https://doaj.org/article/13c6906933c846ea9c6ac806ba133309
Autor:
Su-ding Zhu MD, Jing Zhang MD, Xiao-jing Liu MD, Jun-hui Zhang MD, Bing Wei MD, Wen-yan Wang PhD, Yi-jun Fan MD, Dan Li MD, Yun-xia Cao PhD, Lei Zhan MD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 21 (2022)
Aims: The NOD-like receptor (NLR) family, caspase recruitment (CARD) domain containing 5 (NLRC5) was dysregulated in endometrial cancer (EC). However, the potential regulatory mechanisms of NLRC5 in EC remained unclear. We aimed to explore whether NL
Externí odkaz:
https://doaj.org/article/bf87b96e92f84aa4a3a3ccb3823f01f3
Publikováno v:
International Journal of Ophthalmology, Vol 12, Iss 11, Pp 1688-1692 (2019)
AIM: To detect the possible role of interleukin (IL)-26 in diabetic retinopathy (DR) patients. METHODS: Subjects were divided into diabetes without retinopathy (DWR) group (n=20), non-proliferative diabetic retinopathy (NPDR) group (n=20), prolifera
Externí odkaz:
https://doaj.org/article/556be4700b9d4550981f556a736656b9
Publikováno v:
Cancer Cell International, Vol 19, Iss 1, Pp 1-17 (2019)
Abstract Background Ovarian cancer is known as one of the most common cancers in the world among women. ST6GALNAC1 is highly expressed in cancer stem cells (CSCs), which correlates to high tumor-initiating, self-renewal and differentiation abilities.
Externí odkaz:
https://doaj.org/article/99e182e173d94d63b0f6470e1ed288af
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 955-972 (2019)
In this article, a series of novel quinoline derivatives of ursolic acid (UA) bearing hydrazide, oxadiazole, or thiadiazole moieties were designed, synthesised, and screened for their in vitro antiproliferative activities against three cancer cell li
Externí odkaz:
https://doaj.org/article/7a1b3114cf914ae8b6294b66857b3d57
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1544-1561 (2019)
In this paper, a series of novel 1H-dibenzo[a,c]carbazole derivatives of dehydroabietic acid bearing different N-(piperazin-1-yl)alkyl side chains were designed, synthesised and evaluated for their in vitro anticancer activities against three human h
Externí odkaz:
https://doaj.org/article/c01818ef3d37430586768fd275eee8f7
Autor:
Qi-Shun Wu, Qing He, Jian-Qiang He, Jun Chao, Wen-Yan Wang, Yan Zhou, Ji-Zhuang Lou, Wei Kong, Jun-Feng Chen
Publikováno v:
Renal Failure, Vol 40, Iss 1, Pp 252-258 (2018)
Left ventricular hypertrophy (LVH) is a common abnormality in hemodialysis (HD) patients. Mitochondrial dysfunction contributes to the progression of LVH. As an inner mitochondrial membrane structural protein, mitofilin plays a key role in maintainin
Externí odkaz:
https://doaj.org/article/e88ee86f34d1481d8cb55007d75205ae