Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Wen-Yan W"'
Publikováno v:
Zhipu Xuebao, Vol 45, Iss 5, Pp 666-672 (2024)
Inflammation can occur at any time in many diseases, and affect the activity of metabolism enzymes and transporters, so change the blood concentration and therapeutic effect of therapeutic drugs. Therefore, it is necessary to study the metabolic chan
Externí odkaz:
https://doaj.org/article/30d8b55137144100bcbb3a0ffbf6ce7c
Autor:
Lei Zhan, Jing Zhang, Jun-Hui Zhang, Xiao-Jing Liu, Bao Guo, Jia-Hua Chen, Zhen-Hai Tang, Wen-Yan Wang, Qing-Yuan Wang, Bing Wei, Yun-Xia Cao
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-5 (2023)
Abstract Background N6-methyladenosine (m6A) methylation is the most abundant chemical posttranscriptional modification of mRNA, and it is associated with the regulation of the immune response to tumors. However, the function of m6A modification in t
Externí odkaz:
https://doaj.org/article/b68b3202e28d4ea982f1f074e697d05f
NLRC5 potentiates anti-tumor CD8+ T cells responses by activating interferon-β in endometrial cancer
Autor:
Jing Zhang, Bao Guo, Jia-Hua Chen, Xiao-Jing Liu, Jun-Hui Zhang, Hai-Qing Zhu, Wen-Yan Wang, Zhen-Hai Tang, Bing Wei, Yun-Xia Cao, Lei Zhan
Publikováno v:
Translational Oncology, Vol 36, Iss , Pp 101742- (2023)
Objectives: NLR family CARD domain containing 5 (NLRC5) could promote major histocompatibility complex class I (MHC-I)-dependent CD8+ T cell-mediated anticancer immunity. In this study, the immunosurveillance role and underlying mechanisms of NLRC5 i
Externí odkaz:
https://doaj.org/article/1fe009f5924d4389b7cd3090393e42fc
Autor:
Dai Cao, Die Chen, Jiang-Nan Xia, Wen-Yan Wang, Guo-Yuan Zhu, Li-Wen Chen, Chuantao Zhang, Bo Tan, Hui Li, Ying-Wei Li
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 155, Iss , Pp 113705- (2022)
Lung cancer is the leading cause of cancer-related death worldwide. The development of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) and immune checkpoint inhibitors (ICIs) has brought favorable survival benefits to patients
Externí odkaz:
https://doaj.org/article/13c6906933c846ea9c6ac806ba133309
Autor:
Su-ding Zhu MD, Jing Zhang MD, Xiao-jing Liu MD, Jun-hui Zhang MD, Bing Wei MD, Wen-yan Wang PhD, Yi-jun Fan MD, Dan Li MD, Yun-xia Cao PhD, Lei Zhan MD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 21 (2022)
Aims: The NOD-like receptor (NLR) family, caspase recruitment (CARD) domain containing 5 (NLRC5) was dysregulated in endometrial cancer (EC). However, the potential regulatory mechanisms of NLRC5 in EC remained unclear. We aimed to explore whether NL
Externí odkaz:
https://doaj.org/article/bf87b96e92f84aa4a3a3ccb3823f01f3
Autor:
Yang Wang, Li Yi, Li-Yun Sun, Yi-Chen Liu, Wen-Yan Wen, Xiao-Kang Li, Jing-Jing Mei, Ke Ding, Ting-Cai Wu, Daniel Grenier
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 53, Iss 2, Pp 234-239 (2020)
Background: Streptococcus suis (SS) is a major swine pathogen and a serious zoonotic pathogen causing septicemia and meningitis in piglets and humans. Using an immunoproteomic approach, we previously brought evidence that ornithine carbamoytransferas
Externí odkaz:
https://doaj.org/article/b13005afd6404dd7a27b2352f92f42e1
Autor:
Ya-Jun Wang, Jie Su, Jing-Jing Yu, Mei-Qiu Yan, Meng-Lin Shi, Qi-Di Huang, Bo Li, Wen-Yan Wu, Rong-Shuang Xia, Si-Fan Li, Su-Hong Chen, Gui-Yuan Lv
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
As the number of patients with metabolic hypertension (MH) is increasing, there is an essential require for global measures to prevent and treat MH. Flavonoids such as buddleoside (BUD) from Chrysanthemum indicum L. are the main pharmacological compo
Externí odkaz:
https://doaj.org/article/0766d90e474f42b7b3e3285c7b240236
Publikováno v:
International Journal of Ophthalmology, Vol 12, Iss 11, Pp 1688-1692 (2019)
AIM: To detect the possible role of interleukin (IL)-26 in diabetic retinopathy (DR) patients. METHODS: Subjects were divided into diabetes without retinopathy (DWR) group (n=20), non-proliferative diabetic retinopathy (NPDR) group (n=20), prolifera
Externí odkaz:
https://doaj.org/article/556be4700b9d4550981f556a736656b9
Publikováno v:
Cancer Cell International, Vol 19, Iss 1, Pp 1-17 (2019)
Abstract Background Ovarian cancer is known as one of the most common cancers in the world among women. ST6GALNAC1 is highly expressed in cancer stem cells (CSCs), which correlates to high tumor-initiating, self-renewal and differentiation abilities.
Externí odkaz:
https://doaj.org/article/99e182e173d94d63b0f6470e1ed288af
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 955-972 (2019)
In this article, a series of novel quinoline derivatives of ursolic acid (UA) bearing hydrazide, oxadiazole, or thiadiazole moieties were designed, synthesised, and screened for their in vitro antiproliferative activities against three cancer cell li
Externí odkaz:
https://doaj.org/article/7a1b3114cf914ae8b6294b66857b3d57