Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Wen-Xiu Qiu"'
Autor:
Wen Song, Fan Yang, Hang Yang, Yi Xu, Shu-Jun Song, Yan Meng, Si-Tian Wei, Tao Wan, Ying Zhou, Bin Zhou, Jing Kuang, Tao Yu, Wen-Xiu Qiu
Publikováno v:
Journal of Medicinal Chemistry. 65:14832-14842
Compared to the activation of acquired immunity by the immune checkpoint blockade, the activation of innate immunity via anti-phagocytosis checkpoint blockade could significantly increase the beneficiary population of immunotherapy. However, the acti
Autor:
Wen Song, Jing-Jing Hu, Shu-Jun Song, Yi Xu, Hang Yang, Fan Yang, Ying Zhou, Tao Yu, Wen-Xiu Qiu
Publikováno v:
ACS Applied Materials & Interfaces. 14:42931-42939
Immune checkpoint blockade (ICB) has been hailed as the hope for conquering cancer as ICB could produce a significant and durable response to tumor cells. However, the high cost and severe side effects of ICB drugs limited their application for furth
Autor:
Wen Song, Shu-Jun Song, Jing Kuang, Hang Yang, Tao Yu, Fan Yang, Tao Wan, Yi Xu, Si-Tian Wei, Mu-Xuan Li, Yuan Xiong, Ying Zhou, Wen-Xiu Qiu
Publikováno v:
ACS nano. 16(10)
The number of patients who benefit from acquired immunotherapy is limited. Stimulator of interferon genes (STING) signal activation is a significant component to enhance innate immunity, which has been used to realize broad-spectrum immunotherapy. He
Publikováno v:
Biomaterials. 194:84-93
This paper reported on a two-photon excited nanocomposite FCRH to overcome tumor hypoxia for enhanced photodynamic therapy (PDT). Through modified by ruthenium (Ⅱ) complex (Ru(bpy)32+) and hyperbranched conjugated copolymer with poly (ethylene glyc
Autor:
Xian-Zheng Zhang, Wen-Xiu Qiu, Guo-Feng Luo, Si Chen, Wei-Hai Chen, Qi Lei, Lei Rong, Hui-Zhen Jia
Publikováno v:
ACS biomaterials scienceengineering. 1(11)
In this paper, adamantane (Ad) substituted reduction-sensitive polyethylenimine (Ad-b-SS-PEI600) was used as cationic polymer gene vector for DNA loading. And then the α,β CD dimers were applied as the bridges between the Ad-b-SS-PEI600/DNA polyple
Publikováno v:
ACS biomaterials scienceengineering. 5(2)
The only treatment for cataract in clinic is the clouded lens removal combined with artificial lens implantation. In this study, nifedipine (NFP), a classic vasodilator, was loaded in a U.S. FDA-approved polymer PLA–PEG to form NFP-loaded PLA–PEG
Autor:
Si Chen, Wen-Xiu Qiu, Paul K. Chu, Meng-Yi Liu, Penghui Li, Qi Lei, Di-Wei Zheng, Xian-Zheng Zhang, Zushun Xu, Xian Chen, Quanyuan Zhang, Yu-Xue Ding
Publikováno v:
Journal of materials chemistry. B. 3(43)
Magnetite (Fe3O4) microcapsules prepared by layer-by-layer self-assembly are investigated as multi-functional magnetic resonance imaging contrast agents and drug carriers. They are produced by host–guest interactions and Coulombic force from differ
Publikováno v:
Journal of materials chemistry. B. 6(10)
In this work, a cellular/intranuclear dual-targeting nanoplatform was designed for tumor photothermal therapy (PTT). As a photo-to-heat nanoheater, a gold nanostar (GNS) was decorated with a nuclear localization sequence (NLS) to form GNS-NLS which p
Autor:
Shi-Ying Li, Jun Feng, Lu Zhang, Li-Han Liu, Ming-Kang Zhang, Wen-Xiu Qiu, Chi Zhang, Fan Gao, Xian-Zheng Zhang, Bo-Ru Xie
Publikováno v:
Biomaterials. 161:81-94
Nowadays, cell membrane targeting therapy has drawn much attention for its high anti-tumor effect by avoiding the cellular barriers. In this study, therapeutic agent conjugated chimeric peptide (Cp) was anchored in cracked cancer cell membranes (CCCM
Autor:
Wen-Xiu Qiu, Wen-Long Liu, Shi-Ying Li, Hong Cheng, Xian-Zheng Zhang, Chu-Xin Li, Ming-Kang Zhang, Bo-Ru Xie, Xiao-Shuang Wang
Publikováno v:
Biomaterials. 151:1-12
In this report, a biomimetic theranostic oxygen (O2)-meter (cancer cell membrane@Pt(II) porphyrinic-metal organic framework, designated as mPPt) was constructed for cancer targeted and phosphorescence image-guided photodynamic therapy (PDT). mPPt pre