Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Wen-Wen Low"'
Autor:
Joshua L. C. Wong, Maria Romano, Louise E. Kerry, Hok-Sau Kwong, Wen-Wen Low, Stephen J. Brett, Abigail Clements, Konstantinos Beis, Gad Frankel
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/ccf0e00d772d40d0bf6107b24fa207b9
Autor:
Joshua L. C. Wong, Maria Romano, Louise E. Kerry, Hok-Sau Kwong, Wen-Wen Low, Stephen J. Brett, Abigail Clements, Konstantinos Beis, Gad Frankel
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Abstract Carbapenem-resistance in Klebsiella pneumoniae (KP) sequence type ST258 is mediated by carbapenemases (e.g. KPC-2) and loss or modification of the major non-selective porins OmpK35 and OmpK36. However, the mechanism underpinning OmpK36-media
Externí odkaz:
https://doaj.org/article/048fe9334b3d4543a8b1643b71a6d1c0
Horizontal gene transfer via conjugation plays a major role in bacterial evolution. In F-like plasmids, efficient DNA transfer is mediated by close association between donor and recipient bacteria. This process, known as mating pair stabilization (MP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fad0190aad8d9c2218aca70a720e630a
https://doi.org/10.1101/2023.02.09.527952
https://doi.org/10.1101/2023.02.09.527952
Autor:
Joshua L C, Wong, Sophia, David, Julia, Sanchez-Garrido, Jia Z, Woo, Wen Wen, Low, Fabio, Morecchiato, Tommaso, Giani, Gian Maria, Rossolini, Konstantinos, Beis, Stephen J, Brett, Abigail, Clements, David M, Aanensen, Silvi, Rouskin, Gad, Frankel
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(38)
Outer membrane porins in Gram-negative bacteria facilitate antibiotic influx. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ca2c5127907a1fd7214b7f5c4a2d1d38
https://pubmed.ncbi.nlm.nih.gov/36095213
https://pubmed.ncbi.nlm.nih.gov/36095213
Autor:
Joshua L. C. Wong, Sophia David, Julia Sanchez-Garrido, Jia Z. Woo, Wen Wen Low, Fabio Morecchiato, Tommaso Giani, Gian Maria Rossolini, Konstantinos Beis, Stephen J. Brett, Abigail Clements, David M. Aanensen, Silvi Rouskin, Gad Frankel
Outer membrane porins in Gram-negative bacteria facilitate antibiotic influx. In Klebsiella pneumoniae , modifications in the porin OmpK36 are implicated in increasing resistance to carbapenems. An analysis of large K. pneumoniae genome collections,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::847586ae1fc8a6724afe79b544b6f06e
http://hdl.handle.net/10044/1/98978
http://hdl.handle.net/10044/1/98978
Autor:
Joshua L. C. Wong, Sophia David, Julia Sanchez-Garrido, Jia Z. Woo, Wen Wen Low, Fabio Morecchiato, Tommaso Giani, Gian Maria Rossolini, Stephen J. Brett, Abigail Clements, David M Aanensen, Silvi Rouskin, Gad Frankel
Outer membrane porins in Gram-negative bacteria facilitate antibiotic influx. In Klebsiella pneumoniae (KP), modifications in the porin OmpK36 are implicated in increasing resistance to carbapenems. Analysis of large KP genome collections, encompassi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65415610a35be22e08c941fb9e859147
https://doi.org/10.1101/2022.01.05.475072
https://doi.org/10.1101/2022.01.05.475072
Autor:
Wen Wen Low, Joshua L. C. Wong, Leticia C. Beltran, Chloe Seddon, Sophia David, Hok-Sau Kwong, Tatiana Bizeau, Fengbin Wang, Alejandro Peña, Tiago R. D. Costa, Bach Pham, Min Chen, Edward H. Egelman, Konstantinos Beis, Gad Frankel
Publikováno v:
Nature microbiology. 7(7)
Bacterial conjugation mediates contact-dependent transfer of DNA from donor to recipient bacteria, thus facilitating the spread of virulence and resistance plasmids. Here we describe how variants of the plasmid-encoded donor outer membrane (OM) prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b29bc3d57afc759273237c1a9653ca
https://pubmed.ncbi.nlm.nih.gov/35697796
https://pubmed.ncbi.nlm.nih.gov/35697796
Autor:
Wong, Joshua L. C., David, Sophia, Sanchez-Garrido, Julia, Jia Z. Woo, Wen Wen Low, Morecchiato, Fabio, Giani, Tommaso, Rossolini, Gian Maria, Beis, Konstantinos, Brett, Stephen J., Clements, Abigail, Aanensen, David M., Rouskin, Silvi, Frankel, Gad
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 9/20/2022, Vol. 119 Issue 38, p1-12, 28p
Publikováno v:
Structure
Summary Conjugative pili are important in mediating bacterial conjugation and horizontal gene transfer. Since plasmid transfer can include antibiotic-resistance genes, conjugation is an important mechanism in the spread of antibiotic resistance. Fila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef78571ebe412f25a56586b2424a9e19
https://pubmed.ncbi.nlm.nih.gov/32916103
https://pubmed.ncbi.nlm.nih.gov/32916103
Autor:
Alejandro Peña, Tiago Rd Costa, Chloe M Seddon, Konstantinos Beis, Gad Frankel, Wen Wen Low, Joshua Lc Wong
We investigated the mechanism of conjugal transfer of the endemic Klebsiella pneumoniae carbapenem resistance plasmid, pKpQIL. Transfer efficiency of this plasmid was found to be dependent on the expression of the major outer membrane porin, OmpK36,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::569b5cd62933e5381dbb8de77c0e362b
https://doi.org/10.1101/2020.07.01.180638
https://doi.org/10.1101/2020.07.01.180638