Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Wen-Song Tan"'
Publikováno v:
Bioresources and Bioprocessing, Vol 10, Iss 1, Pp 1-17 (2023)
Abstract During the ex vivo expansion of umbilical cord-derived mesenchymal stem cells (hUCMSCs) in a stirred tank bioreactor, the formation of cell–microcarrier aggregates significantly affects cell proliferation and physiological activity, making
Externí odkaz:
https://doaj.org/article/93c8ad40db1f44a1b7051ef5c30298dc
Autor:
Qi Wang, Jian Luo, Beibei Li, Qian Ye, Wenting Xu, Feixia Gao, Linting Zhou, Wenyue Lu, Wen-Song Tan, Xiuling Li
Publikováno v:
Vaccines, Vol 12, Iss 3, p 287 (2024)
Compared with the traditional vaccine produced in embryonated chicken eggs, cell-based manufacturing represented by the Madin–Darby canine kidney (MDCK) cell line has a larger production scale and reduces the risk of egg shortage in a pandemic. Est
Externí odkaz:
https://doaj.org/article/5d8245443cc9491f913f566675e44612
Publikováno v:
Bioresources and Bioprocessing, Vol 9, Iss 1, Pp 1-13 (2022)
Abstract Robust ex vivo expansion of NK-92 cells is essential for clinical immunotherapy. The vitamin B group is critical for the expansion and function of immune cells. This study optimized a vitamin combination by response surface methodology based
Externí odkaz:
https://doaj.org/article/286309bcf6904fa190a821709747bc82
Publikováno v:
Bioresources and Bioprocessing, Vol 9, Iss 1, Pp 1-11 (2022)
Abstract The application of natural killer (NK) cells as potential antitumor effector cells appears to be valuable for immunotherapies. However, the clinical use of NK cells is limited because the technical difficulties associated with mass productio
Externí odkaz:
https://doaj.org/article/cc00f78718e5414aa4ba68634bfcc951
Publikováno v:
Bioresources and Bioprocessing, Vol 9, Iss 1, Pp 1-14 (2022)
Abstract Epigallocatechin-3-gallate (EGCG) is a plant-derived flavonoid compound with the ability to promote the differentiation of human bone marrow-derived mesenchymal stem cells (MSCs) into osteoblasts. However, the effect of EGCG on the osteogeni
Externí odkaz:
https://doaj.org/article/b1f8ce97fe91492ea22b5e6e94309adc
Publikováno v:
Bioresources and Bioprocessing, Vol 8, Iss 1, Pp 1-11 (2021)
Abstract Effective nutrient transport and appropriate mechanical stimulation play important roles in production of tissue-engineered bone grafts. In this study, an experimental set-up for magnetic-driven dynamic culture of cells was designed to mimic
Externí odkaz:
https://doaj.org/article/f9a99ad1345c48098d395ef80033b16a
Publikováno v:
Bioresources and Bioprocessing, Vol 7, Iss 1, Pp 1-12 (2020)
Abstract The use of H9N2 subtype avian influenza vaccines is an effective approach for the control of the virus spread among the poultry, and for the upgrading of vaccine manufacturing, cell culture-based production platform could overcome the limita
Externí odkaz:
https://doaj.org/article/a3417f3aef664a329f4dd1bcbcc486c8
Publikováno v:
Emerging Microbes and Infections, Vol 9, Iss 1, Pp 78-87 (2020)
ABSTRACTThe H7N9 influenza virus has been circulating in China for more than six years. The neuraminidase (NA) has gained great concern for the development of antiviral drugs, therapeutic antibodies, and new vaccines. In this study, we screened seven
Externí odkaz:
https://doaj.org/article/b6967c4e02894ecb8493d536d2b55c4c
Publikováno v:
Bioresources and Bioprocessing, Vol 6, Iss 1, Pp 1-10 (2019)
Abstract The FGF/MEK/ERK and Wnt/β-catenin signaling pathways have previously been proved to regulate mouse embryonic stem cell (mESCs) function. However, the relationships between these two pathways, especially their different functions on prolifer
Externí odkaz:
https://doaj.org/article/c9d2ee254cdf45a783f0e7b1928d4a65
Autor:
Huijie Niu, Jiaqi Wang, Mengjuan Liu, Miaomiao Chai, Liang Zhao, Xuping Liu, Li Fan, Wen-Song Tan
Publikováno v:
Bioresources and Bioprocessing, Vol 5, Iss 1, Pp 1-8 (2018)
Abstract Background Charge heterogeneity is one of the most critical quality attributes of antibodies, which has strong influence on drug’s biological activity and safety. Finding out the key components that affecting charge variants is of great si
Externí odkaz:
https://doaj.org/article/37644ca7204e41d591cf5eb181c19df5