Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Wen-Qi Chen"'
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-8 (2024)
Abstract Objective Sotos syndrome (SOTOS) is an uncommon genetic condition that manifests itself with the following distinctive features: prenatal overgrowth, facial abnormalities, and intellectual disability. This disorder is often associated with h
Externí odkaz:
https://doaj.org/article/af3f6736c0d341faa6f2d6eb9fafcf22
Autor:
Kai Yang, Ying-yi Luan, Shan Wang, You-sheng Yan, Yi-peng Wang, Jue Wu, Yong-qing Sun, Jing Zhang, Wen-qi Chen, Yu-lan Xiang, Ze-lu Li, Dong-liang Zhang, Cheng-hong Yin
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109358- (2024)
Summary: Mesenchymal stem cell (MSC)-mediated coupling of osteogenesis and angiogenesis is a critical phenomenon in bone formation. Herein, we investigated the role and mechanism of SGMS1 in the osteogenic differentiation of MSCs and, in combination
Externí odkaz:
https://doaj.org/article/c956789ee343452f8d9453b8da94352a
Autor:
Qing‐bing He, Cai‐hong Wu, Dong‐lan Sun, Jia‐yu Yuan, Hua‐ying Hu, Kai Yang, Wen‐qi Chen, You‐sheng Yan, Guang‐yue Yin, Jing Zhang, Ya‐zhou Li
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 12, Iss 3, Pp n/a-n/a (2024)
Abstract Background The MYH3‐associated myosinopathies comprise a spectrum of rare neuromuscular disorders mainly characterized by distal arthrogryposis with or without other features like pterygia and vertebrae fusion. CPSKF1B (contractures, ptery
Externí odkaz:
https://doaj.org/article/cd96c595951949e38729fc14258a8b2d
Autor:
Kai Yang, Jue Wu, Shang Li, Shan Wang, Jing Zhang, Yi-peng Wang, You-sheng Yan, Hua-ying Hu, Ming-fang Xiong, Chao-bo Bai, Yong-qing Sun, Wen-qi Chen, Yang Zeng, Jun-liang Yuan, Cheng-hong Yin
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-15 (2023)
Abstract Hippocampal neuronal damage may induce cognitive impairment. Neurotrophic tyrosine kinase receptor 1 (NTRK1) reportedly regulates neuronal damage, although the underlying mechanism remains unclear. The present study aimed to investigate the
Externí odkaz:
https://doaj.org/article/59839e9a0a1342d5a4955354421fbdd3
Autor:
Liu-Chun Wang, Li-Chan Chang, Wen-Qi Chen, Yi-Hsin Chien, Po-Ya Chang, Chih-Wen Pao, Yin-Fen Liu, Hwo-Shuenn Sheu, Wen-Pin Su, Chen-Hao Yeh, Chen-Sheng Yeh
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Single-atom catalysts emerge as nanocatalytic medicine in chemodynamic therapy but suffer from inefficient kinetics for the production of reactive oxygen species because of the cell’s antioxidative mechanisms. Here, the authors employ a galvanic re
Externí odkaz:
https://doaj.org/article/bdc2a6f7a17c4440be0c232737c576ba
Autor:
Yi Yu, Yu‐Feng Zou, Run‐Qi Hong, Wen‐Jie Chen, Liang Chen, Wen‐Qi Chen, Hui‐Peng Wang, Yuan Yu
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 38, Iss 10, Pp 981-991 (2022)
Abstract Gemcitabine resistance (GR) in pancreatic cancer (PC) results in poor patient outcomes. SMAD family member (Smad4) dysregulation is a significant role of GR in PC, and EZH2 is involved in Smad4 expression in tumor progression. Interestingly,
Externí odkaz:
https://doaj.org/article/8e18f71a194d4ed1a132f5e5acb58da2
Autor:
Kai Yang, Li‐Man Fu, Xiao‐Yang Chu, Jing Zhang, Wen‐Qi Chen, You‐Sheng Yan, Yi‐Peng Wang, Dong‐Liang Zhang, Cheng‐Hong Yin, Qing Guo
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 11, Iss 7, Pp n/a-n/a (2023)
Abstract Background Miller syndrome is a rare type of postaxial acrofacial dysostosis caused by biallelic mutations in the DHODH gene, which is characterized mainly by craniofacial malformations of micrognathia, orofacial clefts, cup‐shaped ears, a
Externí odkaz:
https://doaj.org/article/febe9e52bd1948dcb157e822212bc045
Publikováno v:
ACS Omega, Vol 6, Iss 8, Pp 5569-5581 (2021)
Externí odkaz:
https://doaj.org/article/3931baf1f2f6411abea247bfe1ef6609
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 10, Pp n/a-n/a (2020)
Abstract Background Distal arthrogryposis (DA) is a group of rare Mendelian conditions that demonstrate heterogeneity with respect to genetics and phenotypes. Ten types of DAs, which collectively involve six genes, have been reported. Among them, the
Externí odkaz:
https://doaj.org/article/d3667569b42340eeb2569fdaac683c21
Autor:
Yang Lv, Ning Pu, Wei-lin Mao, Wen-qi Chen, Huan-yu Wang, Xu Han, Yuan Ji, Lei Zhang, Da-yong Jin, Wen-Hui Lou, Xue-feng Xu
Publikováno v:
Endocrine Connections, Vol 7, Iss 11, Pp 1178-1185 (2018)
Aim: We aim to investigate the clinical characteristics of the rectal NECs and the prognosis-related factors and construct a nomogram for prognosis prediction. Methods: The data of 41 patients and 1028 patients with rectal NEC were retrieved respect
Externí odkaz:
https://doaj.org/article/60f889caa5a641f4a57ffab0131e100f