Zobrazeno 1 - 10
of 257
pro vyhledávání: '"Wen-Pin Chen"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionNon-Hodgkin’s lymphoma (NHL) encompasses a diverse group of lymphoma subtypes with a wide range in disease course. Previous studies show that hypogammaglobulinemia in treatment-naïve patients is associated with poorer survival in high
Externí odkaz:
https://doaj.org/article/85444e82a0594c84b0ab540f6faf24cd
Autor:
Michael B. Lilly, Chunli Wu, Yu Ke, Wen‐Pin Chen, Adam C. Soloff, Kent Armeson, Noriko N. Yokoyama, Xiaotian Li, Liankun Song, Ying Yuan, Christine E. McLaren, Xiaolin Zi
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 3, Pp n/a-n/a (2024)
Abstract Purpose Our preclinical studies showed that lycopene enhanced the anti‐prostate cancer efficacy of docetaxel in animal models. A phase I trial (NCT0149519) was conducted to identify an optimum dose of synthetic lycopene in combination with
Externí odkaz:
https://doaj.org/article/5c65eef1c6c54d5eaf06f95c1a59df0d
Autor:
Jeremy P. Harris MD, MPhil, Jino Park MD, Eric Ku MD, Steven Seyedin MD, Russell Stitzlein MD, Amanda Goldin MD, Wen-Pin Chen MS, Christine McLaren PhD, Allen M. Chen MD, Warren Chow MD
Publikováno v:
Cancer Control, Vol 31 (2024)
Objectives Immunotherapy with immune checkpoint inhibitors has shown only limited success in the management of metastatic soft tissue sarcoma. Overall response rates (ORR) with single agent pembrolizumab were 18% and median PFS was 18 weeks on the cl
Externí odkaz:
https://doaj.org/article/23421601d64348b5b1e00f854fbf53db
Autor:
Chia-Mei Chu, Hsin-Hui Yu, Tsai-Ling Kao, Yi-Hsuan Chen, Hsuan-Hsuan Lu, En-Ting Wu, Yun-Li Yang, Chin-Hsien Lin, Shin-Yu Lin, Meng-Ju Melody Tsai, Yin-Hsiu Chien, Wuh-Liang Hwu, Wen-Pin Chen, Ni-Chung Lee, Chi-Kang Tseng
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-12 (2022)
Abstract Hoyeraal-Hreidarsson syndrome (HHS) is the most severe form of dyskeratosis congenita (DC) and is caused by mutations in genes involved in telomere maintenance. Here, we identified male siblings from a family with HHS carrying a hemizygous m
Externí odkaz:
https://doaj.org/article/9aecb9637b0d4a5bbbfe6204b5fa8c01
Autor:
Yu-Wen Chu, Wen-Pin Chen, Albert C. Yang, Shih-Jen Tsai, Li-Yu Hu, Shyh-Chyang Lee, Yao-Tung Lee, Cheng-Che Shen
Publikováno v:
BMC Psychiatry, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Fractures are a great health issue associated with morbidity, quality of life, life span, and health care expenditure. Fractures are correlated with cardiovascular disease, type 2 diabetes mellitus, cerebrovascular disease, and so
Externí odkaz:
https://doaj.org/article/9de22d49a3d04edda7888a498c516f87
Autor:
Jei-Yie Huang, Yen-Hung Lin, Chung-Lieh Hung, Wen-Pin Chen, Nagara Tamaki, Jeroen J. Bax, Daniel A. Morris, Grigorios Korosoglou, Yen-Wen Wu
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/9bb7712669414537a762c0fba80c8358
Autor:
James C. Barton, Christine E. McLaren, Wen-pin Chen, Grant A. Ramm, Gregory J. Anderson, Lawrie W. Powell, V. Nathan Subramaniam, Paul C. Adams, Pradyumna D. Phatak, Lyle C. Gurrin, John D. Phillips, Charles J. Parker, Mary J. Emond, Gordon D. McLaren
Publikováno v:
Annals of Hepatology, Vol 17, Iss 5, Pp 871-879 (2018)
Introduction and aim. We sought to identify independent risk factors for cirrhosis in HFE p.C282Y homozygotes in a cross-sectional study.Material and methods. We evaluated 368 p.C282Y homozygotes who underwent liver biopsy and compared characteristic
Externí odkaz:
https://doaj.org/article/b614345361c84b339e0dc7dc77a70630
Autor:
Yu-Shuo Wu, Chien-Chang Chen, Chen-Li Chien, Hsing-Lin Lai, Si-Tse Jiang, Yong-Cyuan Chen, Lin-Ping Lai, Wei-Fan Hsiao, Wen-Pin Chen, Yijuang Chern
Publikováno v:
Journal of Biomedical Science, Vol 24, Iss 1, Pp 1-12 (2017)
Abstract Background The type VI adenylyl cyclase (AC6) is a main contributor of cAMP production in the heart. The amino acid (aa) sequence of AC6 is highly homologous to that of another major cardiac adenylyl cyclase, AC5, except for its N-terminus (
Externí odkaz:
https://doaj.org/article/eb06859d5bc34c888bd24cfbfe88efcf
Autor:
Christine E. McLaren, Wen-Pin Chen, Thomas D. O’Sullivan, Daniel L. Gillen, Min-Ying Su, Jeon H. Chen, Bruce J. Tromberg
Publikováno v:
BMC Medical Research Methodology, Vol 17, Iss 1, Pp 1-8 (2017)
Abstract Background We describe a novel strategy for power and sample size determination developed for studies utilizing investigational technologies with limited available preliminary data, specifically of imaging biomarkers. We evaluated diffuse op
Externí odkaz:
https://doaj.org/article/60c64ccddcaf408fa67e48296fa4ab06
Autor:
Christine E McLaren, Wen-Pin Chen, Nadine A Bertalli, Martin B Delatycki, Graham G Giles, Dallas R English, John L Hopper, Katrina J Allen, Lyle C Gurrin
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0214196 (2019)
Homozygosity for the p.C282Y substitution in the HFE protein encoded by the hemochromatosis gene on chromosome 6p (HFE) is a common genetic trait that increases susceptibility to iron overload. McLaren et al. used bivariate mixture modeling to analyz
Externí odkaz:
https://doaj.org/article/f2a14fcb41ca42fcbc257eb0dc56d421