Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Wen-Mei Yan"'
Autor:
Gai Mei, Du, Bi Ping, Luo, Zhi Hua, Hu, Jie Ge, Wu, Wen Mei, Yan, Zheng Qiang, Han, Yu Hong, Zhang, Mao Jun, Liu
Publikováno v:
General and comparative endocrinology. 267
Ghrelin is implicated in the regulation of gastric functional development. The octanoylation of ghrelin is critical for its physiological functions which dependent upon ghrelin O-acyltransferase (GOAT) catalyzation. To investigate the effect of GOAT
Autor:
Wen-mei Yan, Toyokichi Yoshizawa, Junei Kinjo, Y.-M. Chi, Motoyuki Nakamura, Toshihiro Nohara, Fumio Hashimoto, Yu-Ming Chi, X.-Y. Zhao
Publikováno v:
Journal of Asian Natural Products Research. 9:115-118
A novel macrocyclic spermine alkaloid incasine C' (1), along with a known compound incasine C (2), were isolated from the whole plants of Incarvillea sinensis, and their structures were elucidated on the basis of chemical and spectroscopic evidence.
Autor:
Fumio Hashimoto, Wen-mei Yan, Toshihiro Nohara, Shinobu Sakurada, Junei Kinjo, Toyokichi Yoshizawa, Yu-Ming Chi, Motoyuki Nakamura, Xi-Ying Zhao
Publikováno v:
Biological and Pharmaceutical Bulletin. 29:580-584
Our recent study demonstrated that the dimeric structure of alpha-truxillic acid derivatives played an important role in the expression of their anti-inflammatory activities. In the present report, to investigate the correlation between the structure
Autor:
Toyokichi Yoshizawa, Toshihiro Nohara, Xi Ying Zhao, Motoyuki Nakamura, Fumio Hashimoto, Wen Mei Yan, Yu Ming Chi, Shinobu Sakurada, Junei Kinjo
Publikováno v:
Biological and Pharmaceutical Bulletin. 29:489-493
The oral anti-inflammatory activity of 4,4'-dihydroxy-alpha-truxillic acid (1) was compared with that of two other nonsteroidal anti-inflammatory drugs, loxoprofen sodium (LOX) and diclofenac sodium (DIC). The activity of 1 against the inflammatory p
Autor:
Fumio Hashimoto, Akihiko Yonezawa, Toyokichi Yoshizawa, Junei Kinjo, Yu-Ming Chi, Shinobu Sakurada, Toshihiro Nohara, Yumiko Nakasugi, Wen-Mei Yan, Motoyuki Nakamura
Publikováno v:
Planta Medica. 67:114-117
Incarvillateine (1), a new monoterpene alkaloid carrying a characteristic cyclobutane ring, has been found to show significant antinociceptive activity in a formalin-induced pain model in mice. To investigate the correlation between its structure and
Publikováno v:
Phytochemistry. 46:763-769
Autor:
Wen-Mei Yan, Nobuhiro Marubayashi, Masami Yamashita, Toshihiro Nohara, Yu-ming Chi, Fumio Hashimoto
Publikováno v:
Chemical and Pharmaceutical Bulletin. 45:495-498
The absolute configuration of incarvilline (1), an important core compound of a number of alkaloids isolated from Incarvillea sinensis LAM., has been determined by the application of Mosher's method and X-ray crystallographic analysis of incarvilline
Autor:
Wen Mei Yan, Toshihiro Nohara, Motoyuki Nakamura, Xi Ying Zhao, Yu-Ming Chi, Junei Kinjo, Toyokichi Yoshizawa, Fumio Hashimoto, Shinobu Sakurada
Publikováno v:
Biological and Pharmaceutical Bulletin. 28:1989-1991
To determine the antinociceptive mechanism of incarvillateine (INCA), the opiate antagonists nor-binaltorphimine (nor-BNI), beta-funaltrexamine (beta-FNA) and naltrindole (NTI) were pretreated prior to its injection in a formalin test. The antinocice
Publikováno v:
Phytochemistry. 51:595-597
Two new derivatives of monoterpene alkaloids, named incarvillateine C and incarvillateine D which are related to an antinociceptive alkaloid, incarvillateine, were isolated from the aerial parts of Incarvillea sinensis LAM. On the basis of both chemi
Autor:
Motoyuki Nakamura, Yu-Ming Chi, Wen Mei Yan, Yu Cheng Chi, Toshihiro Nohara, Toyokichi Yoshizawa, Fumio Hashimoto, Junei Kinjo, Xi-Ying Zhao
Publikováno v:
Chemicalpharmaceutical bulletin. 53(11)
Method for rapid quantitative analysis of incarvillateine in Incarvillea sinensis by high-performance liquid chromatography (HPLC) has been developed. The sample preparation involves solid phase extraction (SPE) with a mixed-mode reversed-phase and c