Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Wen-Ling Ye"'
Autor:
Chao Li, Hang Li, Wei Su, Yu-bing Wen, Wei Ye, Wen-ling Ye, Jian-fang Cai, Xu-zhen Qin, Xue-mei Li, Xue-wang Li
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-7 (2020)
Abstract Background Cryoglobulinemic glomerulonephritis (CryoGn) caused by hepatitis B virus (HBV) infection was rarely reported. Our study aimed to investigate the clinical features, renal pathology findings, and prognosis in patients with HBV relat
Externí odkaz:
https://doaj.org/article/59a4d0ca92bc4c1f8ebae35fa46cf191
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-5 (2020)
Abstract Background Hemolytic uremic syndrome (HUS), a common subtype of thrombotic microangiopathy (TMA), is characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. Shiga toxin-producing Escherichia coli infect
Externí odkaz:
https://doaj.org/article/b3bc05b1522742d193a676f6fd437704
Autor:
Xingcong Ren, Yan Cheng, Wen-Ling Ye, Yongguang Tao, Shi-long Jiang, Mingzhu Yin, Yi-Di Guan, Dong-Sheng Cao, Jin-Ming Yang, Xin-luan Wang, Kuansong Wang, Yi Zhang
Publikováno v:
Cell Death and Disease, Vol 11, Iss 11, Pp 1-15 (2020)
Cell Death & Disease
Cell Death & Disease
Oncogenic activation of the mTOR signaling pathway occurs frequently in tumor cells and contributes to the devastating features of cancer, including breast cancer. mTOR inhibitors rapalogs are promising anticancer agents in clinical trials; however,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ac368f83e5b9942276872602b1243f
http://link.springer.com/article/10.1038/s41419-020-03153-x
http://link.springer.com/article/10.1038/s41419-020-03153-x
Autor:
Yong-Huan Yun, Wen-Qun Li, Wen-Ling Ye, Alex F. Chen, Jin-Wei Zhang, Su-Qing Yang, Lin Zhang, Liu-Xia Zhang, Dong-Sheng Cao, Zhen-Ke Deng
Publikováno v:
Chemometrics and Intelligent Laboratory Systems. 185:32-40
Heart failure (HF) has become an important social problem that seriously threatens human health due to its high morbidity and mortality. G Protein-Coupled Receptors Kinase 2 (GRK2), as a novel target of heart failure, is overexpressed in the pathogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ddb37b7f55c2fd339a20f694a1451be
https://doi.org/10.1016/j.chemolab.2018.12.015
https://doi.org/10.1016/j.chemolab.2018.12.015
Autor:
Weiwei Xue, Qian Cao, Liu-Xia Zhang, Yi-Di Guan, Dong-Sheng Cao, Yan Cheng, Alex F. Chen, Wen-Ling Ye
Publikováno v:
New Journal of Chemistry. 43:19097-19106
Eukaryotic elongation factor-2 kinase (eEF2K), a calcium/calmodulin-dependent protein kinase, is a potential target for treating cancer. eEF2K can reduce the binding ability of eEF2 to ribosomes by phosphorylating eEF2, thereby inhibiting peptide cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89ef32d0110e870d327cbecd274025e9
https://doi.org/10.1039/c9nj02600b
https://doi.org/10.1039/c9nj02600b
Publikováno v:
Journal of chemical information and modeling. 60(9)
Virtual Screening (VS) based on molecular docking is an efficient method used for retrieving novel hit compounds in drug discovery. However, the accuracy of the current docking scoring function (SF) is usually insufficient. In this study, in order to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04846ad0b13e1b19781767e5976d5881
https://pubmed.ncbi.nlm.nih.gov/32352294
https://pubmed.ncbi.nlm.nih.gov/32352294
Publikováno v:
Briefings in bioinformatics. 22(3)
Scoring functions (SFs) based on complex machine learning (ML) algorithms have gradually emerged as a promising alternative to overcome the weaknesses of classical SFs. However, extensive efforts have been devoted to the development of SFs based on n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32fa559899b07a8c3c147366bc1f8009
https://pubmed.ncbi.nlm.nih.gov/32496540
https://pubmed.ncbi.nlm.nih.gov/32496540
Autor:
Jin-Wei Zhang, Defang Ouyang, Dong-Sheng Cao, Zhen-Ke Deng, Yan Cheng, Lu Liu, Qian Cao, Wen-Ling Ye, Lin Zhang, Li Fu, Hui Wei
Publikováno v:
Molecular pharmaceutics. 16(1)
Hepatotoxicity is a major cause of drug withdrawal from the market. To reduce the drug attrition induced by hepatotoxicity, an accurate and efficient hepatotoxicity prediction system must be constructed. In the present study, we constructed a three-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318344f99c41e092322af251cf7aa670
https://pubmed.ncbi.nlm.nih.gov/30475633
https://pubmed.ncbi.nlm.nih.gov/30475633
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 17, Iss 1, Pp 1-6 (2022)
Abstract Background Studies have reported mixed results on the importance of medial calcar support for the treatment of proximal humeral fractures. The purpose of this study was to compare radiographic and functional outcomes of patients who had disp
Externí odkaz:
https://doaj.org/article/64b96a9a94fb43fbb3dd8aebe1ea6dd5
Publikováno v:
Tissuecell. 49(2 Pt)
In the present study, we examined the morphological features of the adrenal gland in Bactrian camel by means of digital anatomy, light and electron microscopy. Our findings testified that the gland was divided into three parts, capsule, cortex and me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5e3b162635851988c0b6b914dbb6e4
https://pubmed.ncbi.nlm.nih.gov/28320513
https://pubmed.ncbi.nlm.nih.gov/28320513