Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Wen-Liang Song"'
Autor:
Tie-Ning Zhang, Julie E. Goodwin, Bing Liu, Da Li, Ri Wen, Ni Yang, Jing Xia, Han Zhou, Tao Zhang, Wen-Liang Song, Chun-Feng Liu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 17, Iss , Pp 852-866 (2019)
Septic shock with heart dysfunction is very common in intensive care units. However, whether long noncoding RNA (lncRNA) and mRNA profiles differ between patients with and without myocardial depression is unknown. We generated rat models of hypodynam
Externí odkaz:
https://doaj.org/article/4b0c405aca594637b113e3defff42edb
Autor:
Sheng-long Chen, Hui-ying Feng, Hui Xu, Shan-shan Huang, Jiu-feng Sun, Lin Zhou, Jun-lei He, Wen-liang Song, Rui-jie Wang, Xin Li, Ming Fang
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Background: Around the globe, moderate cases account for the largest proportion of all coronavirus disease 2019 (COVID-19) patients, and deteriorated moderate patients contribute the most in mortality. However, published articles failed to address th
Externí odkaz:
https://doaj.org/article/8f5a6576b4444d52bfe5ab52358fdf49
Publikováno v:
Biomolecules, Vol 11, Iss 9, p 1330 (2021)
The sustained release of a water-soluble drug is always a key and important issue in pharmaceutics. In this study, using cellulose acetate (CA) as a biomacromolecular matrix, core-sheath nanofibers were developed for providing a sustained release of
Externí odkaz:
https://doaj.org/article/707d32da5b164552b7d8f5510eeecb96
Autor:
Richard L. Dunbar, Harsh Goel, Sony Tuteja, Wen-Liang Song, Grace Nathanson, Zeeshan Babar, Dusanka Lalic, Joel M. Gelfand, Daniel J. Rader, Gary L. Grove
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 4, Pp 783-797 (2017)
Though cardioprotective, niacin monotherapy is limited by unpleasant cutaneous symptoms mimicking dermatitis: niacin-associated skin toxicity (NASTy). Niacin is prototypical of several emerging drugs suffering off-target rubefacient properties whereb
Externí odkaz:
https://doaj.org/article/a6e5ce3a9f6247d9b5aaf707a782ce65
Autor:
Alanna M. Chamberlain, Yan Gong, Kathryn McAuliffe Shaw, Jiang Bian, Wen‐Liang Song, MacRae F. Linton, Vivian Fonseca, Eboni Price‐Haywood, Emily Guhl, Jordan B. King, Rashmee U. Shah, Jon Puro, Elizabeth Shenkman, Pamala A. Pawloski, Karen L. Margolis, Adrian F. Hernandez, Rhonda M. Cooper‐DeHoff
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 9 (2019)
Background PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitors effectively lower LDL (low‐density lipoprotein) cholesterol and have been shown to reduce cardiovascular outcomes in high‐risk patients. We used real‐world electronic h
Externí odkaz:
https://doaj.org/article/2b0cc7e3c36a4d0d8344b1742715d921
Publikováno v:
Biomolecules, Vol 11, Iss 5, p 635 (2021)
A side-by-side electrospinning process characterized by a home-made eccentric spinneret was established to produce the Janus beads-on-a-string products. In this study, ketoprofen (KET) and methylene blue (MB) were used as model drugs, which loaded in
Externí odkaz:
https://doaj.org/article/3f558c86379b4b70bc671f51829ae836
Autor:
Ming Fang, Wen-hong Zhong, Wen-liang Song, Yi-yu Deng, Duo-meng Yang, Bin Xiong, Hong-ke Zeng, Hua-dong Wang
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Background: Increased permeability of pulmonary capillary is a common consequence of sepsis that leads to acute lung injury. In this connection, ulinastatin, a urinary trypsin inhibitor (UTI), is used clinically to mitigate pulmonary edema caused by
Externí odkaz:
https://doaj.org/article/aada08ec5c464a1bb467bf6ae651de77
Autor:
Wen-Liang Song, Garret A. FitzGerald
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 10, Pp 2586-2594 (2013)
Niacin (nicotinic acid) has been used for decades as a lipid-lowering drug. The clinical use of niacin to treat dyslipidemic conditions is limited by its side effects. Niacin, along with fibrates, are the only approved drugs which elevate high densit
Externí odkaz:
https://doaj.org/article/861ef0675dbe4180a7a58a1af5f604a8
Autor:
Qian Ma, Qiuhua Yang, Jiean Xu, Xiaoyu Zhang, David Kim, Zhiping Liu, Qingen Da, Xiaoxiao Mao, Yaqi Zhou, Yongfeng Cai, Vidhi Pareek, Ha Won Kim, Guangyu Wu, Zheng Dong, Wen-Liang Song, Lin Gan, Chunxiang Zhang, Mei Hong, Stephen J. Benkovic, Neal L. Weintraub, David Fulton, John M. Asara, Issam Ben-Sahra, Yuqing Huo
Publikováno v:
Circulation. 146:1444-1460
Background: Proliferation of vascular smooth muscle cells (VSMCs) is a hallmark of arterial diseases, especially in arterial restenosis after angioplasty or stent placement. VSMCs reprogram their metabolism to meet the increased requirements of lipid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5565f06c97fa4a77b2181d860724fa0
https://doi.org/10.1161/circulationaha.121.058901
https://doi.org/10.1161/circulationaha.121.058901
Publikováno v:
Journal of the American College of Cardiology. 78:1817-1830
Emerging evidence suggests that elevated concentrations of triglyceride-rich lipoprotein remnants (TRLs) derived from hepatic and intestinal sources contribute to the risk of atherosclerotic cardiovascular events. Natural selection studies support a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae0ecae9606f6696b21d2ef63eb8a5a0
https://doi.org/10.1016/j.jacc.2021.08.051
https://doi.org/10.1016/j.jacc.2021.08.051