Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Wen-Li Hsu"'
Autor:
Ching-Ying Wu, Wei-Chiao Chen, Cheng-Hsu Hsieh, Yun-Fang Liang, Wei-Ju Li, Hao Shen, Wei-Yen Wei, Ting-Yu Chou, Yen-Chun Chiu, Hao Huang, Wen-Li Hsu
Publikováno v:
Translational Medicine Communications, Vol 8, Iss 1, Pp 1-12 (2023)
Abstract Background Androgenetic alopecia (AGA), one of the most common types of hair loss, is associated with oxidative stress, inflammation and aging. Derinat, a transient receptor potential canonical channels (TRPCs) inhibitor, restrains TRPCs-med
Externí odkaz:
https://doaj.org/article/1661b2750ba1497a9e0fc610be97490c
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9149 (2024)
Osteoarthritis (OA) is a leading cause of pain and disability worldwide in elderly people. There is a critical need to develop novel therapeutic strategies that can effectively manage pain and disability to improve the quality of life for older peopl
Externí odkaz:
https://doaj.org/article/1c1fc3227fd7454b8961c25dbb388e90
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 2, Iss 5 (2021)
Cancer is an aging-associated disease and caused by genomic instability that is driven by the accumulation of mutations and epimutations in the aging process. Although Ca2+ signaling, reactive oxygen species (ROS) accumulation, DNA damage response (D
Externí odkaz:
https://doaj.org/article/258192e4f04b420685807bed5f8ad514
Autor:
Tun-Chieh Chen, How-Ran Chao, Ching-Ying Wu, Yun-Ru Lai, Chu-Huang Chen, Tohru Yoshioka, Wen-Li Hsu, Ming-Hsien Tsai
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8917 (2021)
Human breast milk lipids have major beneficial effects: they promote infant early brain development, growth and health. To identify the relationship between human breast milk lipids and infant neurodevelopment, multivariate analyses that combined lip
Externí odkaz:
https://doaj.org/article/6755534f9cdf4e698339c4fa5315ba1a
Autor:
Ching-Ying Wu, Wen-Li Hsu, Ming-Hsien Tsai, Jui-Lin Liang, Jian-He Lu, Chia-Jung Yen, Hsin-Su Yu, Mami Noda, Chi-Yu Lu, Chu-Huang Chen, Shian-Jang Yan, Tohru Yoshioka
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Based on the oxidative stress theory, aging derives from the accumulation of oxidized proteins induced by reactive oxygen species (ROS) in the cytoplasm. Hydrogen peroxide (H2O2) elicits ROS that induces skin aging through oxidation of prote
Externí odkaz:
https://doaj.org/article/c4b49102e8a541c6904ff2fe0fb745b0
Autor:
Ching-Ying Wu, Wen-Li Hsu, Ming-Hsien Tsai, Chee-Yin Chai, Chia-Jung Yen, Chu-Huang Chen, Jian-He Lu, Hsin-Su Yu, Tohru Yoshioka
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213400 (2019)
Transforming growth factor-β (TGF-β) is an important target for treating systemic sclerosis (SSc). However, our study revealed three levels of TGF-β1 expression in SSc patients, indicating that inhibiting TGF-β is not sufficient to treat SSc. A p
Externí odkaz:
https://doaj.org/article/b71be99e8ba743489b0280fbadfea7b4
Autor:
Wen-Li Hsu, Jian-He Lu, Mami Noda, Ching-Ying Wu, Jia-dai Liu, Manabu Sakakibara, Ming-Hsien Tsai, Hsin-Su Yu, Ming-Wei Lin, Yaw-Bin Huang, Shian-Jang Yan, Tohru Yoshioka
Publikováno v:
Molecules, Vol 20, Iss 11, Pp 20297-20311 (2015)
Ultraviolet-B (UVB) is one of the most cytotoxic and mutagenic stresses that contribute to skin damage and aging through increasing intracellular Ca2+ and reactive oxygen species (ROS). Derinat (sodium deoxyribonucleate) has been utilized as an immun
Externí odkaz:
https://doaj.org/article/d341c5ed0f644047ba6c8be400458cc1
Autor:
Ching-Chung Tsai, Li-Ching Chang, Shih-Che Huang, Shu-Leei Tey, Wen-Li Hsu, Yu-Tsun Su, Ching-Wen Liu, Tong-Rong Tsai
Publikováno v:
Molecules, Vol 20, Iss 8, Pp 14504-14521 (2015)
Up to 40% of patients with gastroesophageal reflux disease (GERD) suffer from proton pump inhibitor refractory GERD but clinically the medications to strengthen the lower esophageal sphincter (LES) to avoid irritating reflux are few in number. This s
Externí odkaz:
https://doaj.org/article/14bd33dd6ac24df4b9a9ad6cd11341a9
Autor:
Ke-Li Tsai, Wei-Chiao Chang, Mei-Hsien Lee, Jaw-Yan Wang, Ming-Feng Hou, Yao-Ting Tsai, Yii-Her Chou, Siou-Jin Chiu, Wen-Li Hsu, Yuh-Cherng Guo, Che-Mai Chang
Publikováno v:
Molecules, Vol 18, Iss 6, Pp 6584-6596 (2013)
Non-steroidal anti-inflammatory drugs (NSAIDs) were shown to reduce the risk of colorectal cancer recurrence and are widely used to modulate inflammatory responses. Indomethacin is an NSAID. Herein, we reported that indomethacin can suppress cancer c
Externí odkaz:
https://doaj.org/article/406620f4f41a49d0b7771b30a8ab61bf
Autor:
Wei-Chiao Chang, Chiung-Yao Huang, Jyh-Horng Sheu, Ming-Feng Hou, Eric Terry Wang, Che-Mai Chang, Jaw-Yan Wang, Wen-Li Hsu, Siou-Jin Chiu, Yao-Ting Tsai
Publikováno v:
Molecules, Vol 18, Iss 6, Pp 7023-7034 (2013)
Epidermal growth factor receptor (EGFR) is overexpressed in many types of cancer cells. EGFR-mediated signaling involves inflammatory gene expression including cyclooxygenase (COX)-2 and interleukin (IL)-8, and is associated with cancer pathogenesis.
Externí odkaz:
https://doaj.org/article/721dc7509f474517a1c5cb2b93b51f40