SFTSV nucleoprotein mediates DNA sensor cGAS degradation to suppress cGAS-dependent antiviral responses

Autor: Ze-zheng Jiang, Min Chu, Li-na Yan, Wen-kang Zhang, Bang Li, Jiao Xu, Zhong-xin Zhao, Hui-Ju Han, Chuan-min Zhou, Xue-jie Yu

Publikováno v: Microbiology Spectrum, Vol 12, Iss 6 (2024)

ABSTRACT Cyclic GMP-AMP synthase (cGAS) is an important DNA pattern recognition receptor that senses double-stranded DNA derived from invading pathogens or self DNA in cytoplasm, leading to an antiviral interferon response. A tick-borne Bunyavirus, s

Externí odkaz: https://doaj.org/article/0bd7eec072e841ceaebc773887e54295

Performance Analysis of NCSs Under Channel Noise and Bandwidth Constraints

Autor: Xi-Sheng Zhan, Wen-Kang Zhang, Jie Wu, Huai-Cheng Yan

Publikováno v: IEEE Access, Vol 8, Pp 20279-20288 (2020)

This paper investigates the performance limitation of multi-input multi-output (MIMO) networked control systems (NCSs). The communication channel is modeled as a power constrained channel with channel noise and the bandwidth constraints. The optimal

Externí odkaz: https://doaj.org/article/880fee291a634443a2666a1c0e244192

Neutralizing antibodies and cellular immune response after two doses of inactivated SARS-CoV-2 vaccine in China

Autor: Li-Na Yan, Zhong-Xin Zhao, Zhen-Dong Wang, Xiao Xiao, Pan-Pan Liu, Wen-Kang Zhang, Xiao-Lan Gu, Bang Li, Li-Ping Yu, Xue-Jie Yu

Publikováno v: Expert Review of Vaccines. 21:1465-1473

As of 2022, inactivated SARS-CoV-2 vaccines had been used in more than 91 countries. However, limited real world information was available on the immune responses of the inactivated SARS-CoV-2 vaccine.We used SARS-CoV-2 pseudovirues to determine the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60d0fd512b54cf6f940757351b1f3419
https://doi.org/10.1080/14760584.2022.2104714

Applying the Moving Epidemic Method to Establish the Influenza Epidemic Thresholds and Intensity Levels for Age-Specific Groups in Hubei Province, China

Autor: Yuan Jiang, Ye-qing Tong, Bin Fang, Wen-kang Zhang, Xue-jie Yu

Publikováno v: International Journal of Environmental Research and Public Health; Volume 19; Issue 3; Pages: 1677
International Journal of Environmental Research and Public Health, Vol 19, Iss 1677, p 1677 (2022)

Background: School-aged children were reported to act as the main transmitter during influenza epidemic seasons. It is vital to set up an early detection method to help with the vaccination program in such a high-risk population. However, most relati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26bfa1f55fb8832083a4d9cb92379e67

Integrated transcriptome profiling in THP-1 macrophages infected with bunyavirus SFTSV

Autor: Fei Li, Wen-kang Zhang, Xue-jie Yu, Jia-min Yan, Chuan-min Zhou

Publikováno v: Virus Research. 306:198594

Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne bunyavirus that causes an emerging hemorrhagic fever termed SFTS with high mortality. However, knowledge of SFTSV-host interactions is largely limited. Here, we performed a glo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9bd41e5dba1e780ba6755cc10a8610
https://doi.org/10.1016/j.virusres.2021.198594