Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Wen-Juan Tu"'
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 4, Pp 642-648 (2019)
Resting-state functional magnetic resonance imaging has revealed disrupted brain network connectivity in adults and teenagers with cerebral palsy. However, the specific brain networks implicated in neonatal cases remain poorly understood. In this stu
Externí odkaz:
https://doaj.org/article/a125e70c38764a5489e09c61cc2cee5d
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 4, Pp 603-609 (2017)
With improvements in care of at-risk neonates, more and more children survive. This makes it increasingly important to assess, soon after birth, the prognosis of children with hypoxic-ischemic encephalopathy. Computed tomography, ultrasound, and conv
Externí odkaz:
https://doaj.org/article/d5838a83372245efbb288e851acd8a85
Autor:
Wen Juan Tu, Michelle Melino, Jenny Dunn, Robert D. McCuaig, Helle Bielefeldt-Ohmann, Sofiya Tsimbalyuk, Jade K. Forwood, Taniya Ahuja, John Vandermeide, Xiao Tan, Minh Tran, Quan Nguyen, Liang Zhang, Andy Nam, Liuliu Pan, Yan Liang, Corey Smith, Katie Lineburg, Tam H. Nguyen, Julian D. J. Sng, Zhen Wei Marcus Tong, Keng Yih Chew, Kirsty R. Short, Roger Le Grand, Nabila Seddiki, Sudha Rao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract In vitro, ACE2 translocates to the nucleus to induce SARS-CoV-2 replication. Here, using digital spatial profiling of lung tissues from SARS-CoV-2-infected golden Syrian hamsters, we show that a specific and selective peptide inhibitor of nu
Externí odkaz:
https://doaj.org/article/c807331d48fd44e7b2a60c1357a9b798
Autor:
Thiru Prasanna, Laeeq Malik, Robert D. McCuaig, Wen Juan Tu, Fan Wu, Pek Siew Lim, Abel H. Y. Tan, Jane E. Dahlstrom, Philip Clingan, Eugene Moylan, Jeremy Chrisp, David Fuller, Sudha Rao, Desmond Yip
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ObjectiveLysine-Specific Demethylase-1 (LSD1) is overexpressed in breast cancer cells and facilitate mesenchymal properties which may contribute to therapeutic resistance and cancer progression. The purpose of this study was to investigate the safety
Externí odkaz:
https://doaj.org/article/7ccd363096da4ed794e3ded46a555829
Autor:
Wen Juan Tu, Robert D. McCuaig, Michelle Melino, Daniel J. Rawle, Thuy T. Le, Kexin Yan, Andreas Suhrbier, Rebecca L. Johnston, Lambros T. Koufariotis, Nicola Waddell, Emily M. Cross, Sofiya Tsimbalyuk, Amanda Bain, Elizabeth Ahern, Natasha Collinson, Simon Phipps, Jade K. Forwood, Nabila Seddiki, Sudha Rao
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-25 (2021)
Abstract Treatment options for COVID-19 remain limited, especially during the early or asymptomatic phase. Here, we report a novel SARS-CoV-2 viral replication mechanism mediated by interactions between ACE2 and the epigenetic eraser enzyme LSD1, and
Externí odkaz:
https://doaj.org/article/94d2222dd5d142eaabe147edc4a852eb
Autor:
Wen Juan Tu, Robert D. McCuaig, Michelle Melino, Daniel J. Rawle, Thuy T. Le, Kexin Yan, Andreas Suhrbier, Rebecca L. Johnston, Lambros T. Koufariotis, Nicola Waddell, Emily M. Cross, Sofiya Tsimbalyuk, Amanda Bain, Elizabeth Ahern, Natasha Collinson, Simon Phipps, Jade K. Forwood, Nabila Seddiki, Sudha Rao
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/5015f4b9a04d4d998c8e67847e08b80b
Autor:
Kristine Hardy, Corey Smith, Wen Juan Tu, Robert McCuaig, Archana Panikkar, Vijayendra Dasari, Fan Wu, Siok-Keen Tey, Geoffrey R. Hill, Rajiv Khanna, Sudha Rao
Publikováno v:
Blood Advances, Vol 2, Iss 6, Pp 656-668 (2018)
Abstract: Immune reconstitution following hematopoietic stem cell transplantation (HSCT) is critical in preventing harmful sequelae in recipients with cytomegalovirus (CMV) infection. To understand the molecular mechanisms underlying immune reconstit
Externí odkaz:
https://doaj.org/article/d79e142e77da433a926ab44506f0c2b4
Publikováno v:
BMC Immunology, Vol 21, Iss 1, Pp 1-10 (2020)
BMC Immunology
BMC Immunology
Background Cancer cells subvert natural immunosuppression by upregulating the expression of checkpoint proteins and their ligands. For example, tumor cells expressing programmed death-ligand 1 (PD-L1) induce immune cell tolerance to cancers, thereby
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f95570384d1fc5078a17f2e81dfb79
http://link.springer.com/article/10.1186/s12865-020-00353-0
http://link.springer.com/article/10.1186/s12865-020-00353-0
Autor:
Jenny, Dunn, Robert D, McCuaig, Abel H Y, Tan, Wen Juan, Tu, Fan, Wu, Kylie M, Wagstaff, Anjum, Zafar, Sayed, Ali, Himanshu, Diwakar, Jane E, Dahlstrom, Elaine G, Bean, Jade K, Forwood, Sofiya, Tsimbalyuk, Emily M, Cross, Kristine, Hardy, Amanda L, Bain, Elizabeth, Ahern, Riccardo, Dolcetti, Roberta, Mazzieri, Desmond, Yip, Melissa, Eastgate, Laeeq, Malik, Peter, Milburn, David A, Jans, Sudha, Rao
Publikováno v:
Cancers. 14(6)
Protein kinase C (PKC)-θ is a serine/threonine kinase with both cytoplasmic and nuclear functions. Nuclear chromatin-associated PKC-θ (nPKC-θ) is increasingly recognized to be pathogenic in cancer, whereas its cytoplasmic signaling is restricted t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::051427bf623ea13dff1f12cd3d6062b0
https://pubmed.ncbi.nlm.nih.gov/35326747
https://pubmed.ncbi.nlm.nih.gov/35326747
Autor:
Elizabeth Ahern, Nabila Seddiki, Thuy T. Le, Amanda L. Bain, Lambros T. Koufariotis, Nicola Waddell, Emily M. Cross, Daniel J. Rawle, Robert D. McCuaig, Jade K. Forwood, Kexin Yan, Sudha Rao, Michelle Melino, Wen Juan Tu, Andreas Suhrbier, Simon Phipps, Sofiya Tsimbalyuk, Natasha Collinson, Rebecca L Johnston
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-25 (2021)
Cell Discovery
Cell Discovery
Treatment options for COVID-19 remain limited, especially during the early or asymptomatic phase. Here, we report a novel SARS-CoV-2 viral replication mechanism mediated by interactions between ACE2 and the epigenetic eraser enzyme LSD1, and its inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab2ab74d139f1f96629c3e2390051060
https://doi.org/10.1038/s41421-021-00279-w
https://doi.org/10.1038/s41421-021-00279-w