Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Wen-Juan Xia"'
Autor:
Runbin Sun, Yong Mao, Ting Ma, Wen-juan Xia, Guangji Wang, Xiaoyi Yu, Jiye Aa, Chun Ge, Wenjing Xiao
Publikováno v:
Acta Pharmacologica Sinica. 36:259-267
The pentose phosphate pathway (PPP) is involved in the activity of glucose-6-phosphate dehydrogenase (G6PD) and generation of NADPH, which plays a key role in drug metabolism. The aim of this study was to investigate the effects of modulation of the
Publikováno v:
Med. Chem. Commun.. 5:147-152
A novel prodrug of pegylated methotrexate conjugates (PMCs) with a high drug-carrying capability and a redox sensitive drug release mechanism was reported for intracellular drug delivery. The PMC was structured in a H-shape with four molecules of ant
Autor:
Wen-juan Xia, Ting Ma, Runbin Sun, Guangji Wang, Xiaolan Wu, Yong Mao, Wenjing Xiao, Mengjie Li, Xinwen Wang, Bei Cao, Rongrong Gu, Weibin Zha, Xiaoyi Yu, Chun Ge, Chang-xiao Liu, Jian Shi, Tian Zheng, Jiye Aa, Linsheng Liu, Jun Zhou
Publikováno v:
Acta Pharmacologica Sinica. 34:1349-1358
20(S)-Ginsenoside Rh2 (Rh2) has shown potent inhibition on P-glycoprotein (P-gp), while most HIV protease inhibitors are both substrates and inhibitors of P-gp and CYP3A4. The aim of this study was to investigate the potential pharmacokinetic interac
Autor:
Yanyan Song, Yongyong Li, Xiaojun Cai, Xue-Quan Li, Haiqing Dong, Aijun Shen, Chunyan Dong, Wen-Juan Xia, Donglu Shi, Huiyun Wen
Publikováno v:
Small. 8:760-769
In biomedical applications, polyethylene glycol (PEG) functionalization has been a major approach to modify nanocarriers such as nano-graphene oxide for particular biological requirements. However, incorporation of a PEG shell poses a significant dif
Publikováno v:
Polymer. 52:3580-3586
A novel reduction-sensitive sheddable micelle based on disulfide-linked hybrid PEG-polypeptide mPEG-SS-Pleu was demonstrated for intracellular drug delivery. These micelles are composed of an mPEG shell and polypeptide core, characterized by FT-IR, 1
Publikováno v:
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 29(5)
To provide some new evidences for the identification of medicinal materials of Curcuma.Microscopic observation was made to characterize the rhizomes of Curcuma.There were no obvious histological and morphological differences among the rhizomes of Cur
Autor:
Haiqing Dong, Yongyong Li, Xiaojun Cai, Donglu Shi, Jin-Hai Yu, Huiyun Wen, Xue-Quan Li, Wen-Juan Xia
Publikováno v:
Journal of Materials Chemistry. 21:14639
Engineered PEG-detachable catiomers were developed as non-viral gene vectors to detach the PEG layers responsive to the intracellular reducing environment. These catiomers were found to exhibit high DNA binding ability and reduced cytotoxicity, as ev
Autor:
Haiqing Dong, Donglu Shi, Yongyong Li, Xiaojun Cai, Giovanni M. Pauletti, Huiyun Wen, Wen-Juan Xia, Xue-Quan Li, Wei-Ming Xue
Publikováno v:
Chemical Communications. 47:8647
A novel amphiphilic camptothecin prodrug that spontaneously arranges into nanomicelles which preferentially release the cytotoxic drug under tumor-relevant reductive conditions is designed.
Autor:
Xiao-Jun Cai, Hai-Qing Dong, Wen-Juan Xia, Hui-Yun Wen, Xue-Quan Li, Jin-Hai Yu, Yong-Yong Li, Dong-Lu Shi
Publikováno v:
Journal of Materials Chemistry; Sep2011, Vol. 21 Issue 38, p14639-14645, 7p